Pirtobrutinib Disease Interactions
There are 2 disease interactions with pirtobrutinib.
Pirtobrutinib (applies to pirtobrutinib) infections
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral
Severe infections (including bacterial, viral, and fungal) as well as opportunistic infections leading to fatal outcomes have been reported while on pirtobrutinib. Antimicrobial prophylaxis and vaccinations are recommended for patients with a high risk for infection. Assess and treat for infection when exhibited. Temporarily hold, decrease the dose, or discontinue therapy as indicated.
Pirtobrutinib (applies to pirtobrutinib) renal impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
Patients with severe renal impairment (eGFR 15 to 29 mL/min) can have increased exposure to pirtobrutinib and require a dosage reduction. No dosage modifications are required in patients with mild or moderate renal impairment.
Switch to professional interaction data
Pirtobrutinib drug interactions
There are 730 drug interactions with pirtobrutinib.
Pirtobrutinib alcohol/food interactions
There is 1 alcohol/food interaction with pirtobrutinib.
Report options
More about pirtobrutinib
- pirtobrutinib consumer information
- Check interactions
- Compare alternatives
- Reviews (5)
- Side effects
- Dosage information
- During pregnancy
- Drug class: BTK inhibitors
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Revlimid
Revlimid is used to treat types of multiple myeloma, mantle cell lymphoma, follicular lymphoma and ...
Velcade
Velcade injection is used to treat multiple myeloma and mantle cell lymphoma. Includes Velcade side ...
Gazyva
Gazyva is used to treat chronic lymphocytic leukemia (CLL) or follicular lymphoma (FL) in adults ...
Treanda
Treanda (bendamustine) is used to treat chronic lymphocytic leukemia and non-Hodgkin lymphoma ...
Imbruvica
Imbruvica (ibrutinib) is used to treat chronic lymphocytic leukemia (CLL), small lymphocytic ...
Rituxan
Rituxan infusion is used to treat certain leukemias and lymphomas and some non-cancer conditions ...
Cyclophosphamide
Cyclophosphamide systemic is used for acute lymphocytic leukemia, acute nonlymphocytic leukemia ...
Rituximab
Rituximab infusion is used to treat certain leukemias and lymphomas and some non-cancer conditions ...
Kesimpta
Kesimpta (ofatumumab) is used to treat relapsing forms of multiple sclerosis. Includes Kesimpta ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
