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Jaypirca Disease Interactions

There are 2 disease interactions with Jaypirca (pirtobrutinib).

Moderate

Pirtobrutinib (applies to Jaypirca) infections

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral

Severe infections (including bacterial, viral, and fungal) as well as opportunistic infections leading to fatal outcomes have been reported while on pirtobrutinib. Antimicrobial prophylaxis and vaccinations are recommended for patients with a high risk for infection. Assess and treat for infection when exhibited. Temporarily hold, decrease the dose, or discontinue therapy as indicated.

References

  1. (2023) "Product Information. Jaypirca (pirtobrutinib)." Lilly, Eli and Company
Moderate

Pirtobrutinib (applies to Jaypirca) renal impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction

Patients with severe renal impairment (eGFR 15 to 29 mL/min) can have increased exposure to pirtobrutinib and require a dosage reduction. No dosage modifications are required in patients with mild or moderate renal impairment.

References

  1. (2023) "Product Information. Jaypirca (pirtobrutinib)." Lilly, Eli and Company

Jaypirca drug interactions

There are 705 drug interactions with Jaypirca (pirtobrutinib).

Jaypirca alcohol/food interactions

There is 1 alcohol/food interaction with Jaypirca (pirtobrutinib).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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