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Nabilone Disease Interactions

There are 4 disease interactions with nabilone:

Moderate

Miscellaneous Antiemetics (Includes Nabilone) ↔ Cardiac Disease

Moderate Potential Hazard, Moderate plausibility

Applies to: Cardiovascular Disease

The use of some antiemetics such as dronabinol and nabilone has been associated with occasional hypotension, possible hypertension, syncope or tachycardia. Therapy with these drugs should be administered cautiously in patients with cardiac disease.

References

  1. "Product Information. Marinol (dronabinol)." Roxane Laboratories Inc, Columbus, OH.
Moderate

Miscellaneous Antiemetics (Includes Nabilone) ↔ Psychoses/Depression

Moderate Potential Hazard, Moderate plausibility

Applies to: Depression, Psychosis

Some antiemetics such as dronabinol and nabilone may precipitate or exacerbate psychotic symptoms or anxiety, depression, hallucinations or psychosis. Therapy with these drugs should be administered cautiously in patients with a history of psychiatric disorders, emotional instability, or depression, and particularly if they are elderly. Careful psychiatric monitoring is advised.

References

  1. "Product Information. Marinol (dronabinol)." Roxane Laboratories Inc, Columbus, OH.
Moderate

Miscellaneous Antiemetics (Includes Nabilone) ↔ Substance Abuse

Moderate Potential Hazard, Moderate plausibility

Applies to: Alcoholism, Drug Abuse/Dependence

Some antiemetics as dronabinol and nabilone have a significant potential for abuse. Therapy with these drugs should be administered cautiously in patients with a history of substance abuse. It may be prudent to refrain from dispensing large quantities of dronabinol to these patients.

References

  1. "Product Information. Marinol (dronabinol)." Roxane Laboratories Inc, Columbus, OH.
Moderate

Nabilone (Includes Nabilone) ↔ Long Qt

Moderate Potential Hazard, Moderate plausibility

Applies to: Long QT Syndrome

The effects of QT prolongation potential by nabilone have not been studies. Caution and monitoring is advised if used in patients with long QT syndrome.

nabilone drug Interactions

There are 561 drug interactions with nabilone

nabilone alcohol/food Interactions

There is 1 alcohol/food interaction with nabilone

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

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