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Magnesium oxide Disease Interactions

There is 1 disease interaction with magnesium oxide.


Magnesium salts (applies to magnesium oxide) renal dysfunction

Major Potential Hazard, High plausibility.

Magnesium is eliminated by the kidney. The serum concentration of magnesium is increased in patients with renal impairment. Magnesium toxicity includes CNS depression, muscular paralysis, respiratory depression, hypotension and prolonged cardiac conduction time. Disappearance of the patellar reflex is a useful clinical sign of magnesium intoxication. Therapy with magnesium should be administered cautiously and dosages should be modified in patients with compromised renal function. Clinical monitoring of serum magnesium levels is recommended.


  1. (2001) "Product Information. Mag-Ox 400 (magnesium oxide)." Blaine Company Inc.
  2. (2001) "Product Information. Uro-Mag (magnesium oxide)." Blaine Company Inc.
  3. (2001) "Product Information. Slow-Mag (magnesium chloride)." Searle
  4. (2001) "Product Information. Magonate (magnesium gluconate)." Fleming and Company
  5. (2001) "Product Information. Losospan (magaldrate)." Whitehall-Robbins
View all 5 references

Magnesium oxide drug interactions

There are 229 drug interactions with magnesium oxide.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.