Phillips' Cramp-free (magnesium oxide) Disease Interactions
There is 1 disease interaction with Phillips' Cramp-free (magnesium oxide):
Magnesium Salts (Includes Phillips' Cramp-free) ↔ Renal Dysfunction
Severe Potential Hazard, High plausibility
Applies to: Renal Dysfunction
Magnesium is eliminated by the kidney. The serum concentration of magnesium is increased in patients with renal impairment. Magnesium toxicity includes CNS depression, muscular paralysis, respiratory depression, hypotension and prolonged cardiac conduction time. Disappearance of the patellar reflex is a useful clinical sign of magnesium intoxication. Therapy with magnesium should be administered cautiously and dosages should be modified in patients with compromised renal function. Clinical monitoring of serum magnesium levels is recommended.
References
- "Product Information. Mag-Ox 400 (magnesium oxide)." Blaine, Erlanger, KY.
- "Product Information. Losospan (magaldrate)." Whitehall-Robbins, Madison, NJ.
- "Product Information. Uro-Mag (magnesium oxide)." Blaine, Erlanger, KY.
- "Product Information. Slow-Mag (magnesium chloride)." Searle, Skokie, IL.
- "Product Information. Magonate (magnesium gluconate)." Fleming and Company, Fenton, MO.
Phillips' Cramp-free (magnesium oxide) drug Interactions
There are 348 drug interactions with Phillips' Cramp-free (magnesium oxide)
See Also
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No information available. |
Do not stop taking any medications without consulting your healthcare provider.
Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. Multum's information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2018 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
