Loncastuximab tesirine Disease Interactions
There are 2 disease interactions with loncastuximab tesirine.
Loncastuximab tesirine (applies to loncastuximab tesirine) hepatic impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Patients with mild hepatic impairment should be monitored for a potential increase of adverse effects when using loncastuximab tesirine. This drug has not been studied in patients with moderate or severe hepatic impairment.
References (1)
- (2021) "Product Information. Zynlonta (loncastuximab tesirine)." ADC Therapeutics America
Loncastuximab tesirine (applies to loncastuximab tesirine) kidney disease
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
The effects of severe renal impairment and end-stage renal disease in the pharmacokinetics of loncastuximab tesirine is unknown.
References (1)
- (2021) "Product Information. Zynlonta (loncastuximab tesirine)." ADC Therapeutics America
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Loncastuximab tesirine drug interactions
There are 528 drug interactions with loncastuximab tesirine.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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