Lactulose Disease Interactions
There are 4 disease interactions with lactulose.
Lactulose (applies to lactulose) galactosemia
Major Potential Hazard, High plausibility.
Since lactulose solution contains galactose, use is contraindicated in patients who require a low galactose diet.
References (4)
- (2002) "Product Information. Chronulac (lactulose)." Hoechst Marion Roussel
- (2002) "Product Information. Cephulac (lactulose)." Hoechst Marion Roussel
- (2001) "Product Information. Duphalac (lactulose)." Solvay Pharmaceuticals Inc
- (2012) "Product Information. Enulose (lactulose)." United Research Laboratories/Mutual Pharmaceutical Company
Laxatives (applies to lactulose) inflammatory bowel disease
Major Potential Hazard, Moderate plausibility.
The use of laxatives is contraindicated in patients with inflammatory bowel disease. Patients with inflammatory bowel disease may experience colonic perforation with use of stimulant laxatives.
References (6)
- (2001) "Product Information. Dulcolax (bisacodyl)." Ciba Self-Medication Inc
- "Product Information. Fleet Bisacodyl (bisacodyl)." Fleet
- "Product Information. Kondremul Plain (mineral oil)." Bristol-Myers Squibb
- (2001) "Product Information. Neoloid (castor oil)." Paddock Laboratories Inc
- (2022) "Product Information. SenoSol-X (senna)." Apothecon Inc
- (2010) "Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates)." Braintree Laboratories
Laxatives (applies to lactulose) intestinal obstruction disorders
Major Potential Hazard, Moderate plausibility. Applicable conditions: Gastrointestinal Obstruction
The use of laxatives is contraindicated in patients with intestinal obstruction disorders. Patients with intestinal obstruction disorders may need their underlying condition treated to correct the constipation. Some laxatives require reduction in the colon to their active form to be effective which may be a problem in patients with intestinal obstruction.
References (8)
- (2001) "Product Information. Dulcolax (bisacodyl)." Ciba Self-Medication Inc
- "Product Information. Fleet Bisacodyl (bisacodyl)." Fleet
- "Product Information. Kondremul Plain (mineral oil)." Bristol-Myers Squibb
- (2001) "Product Information. Fleet Mineral Oil Enema (mineral oil)." Fleet
- (2001) "Product Information. Citrucel (methylcellulose)." SmithKline Beecham
- (2001) "Product Information. Fleet Babylax (glycerin)." Alcon Laboratories Inc
- (2022) "Product Information. SenoSol-X (senna)." Apothecon Inc
- (2010) "Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates)." Braintree Laboratories
Lactulose (applies to lactulose) diabetes
Moderate Potential Hazard, High plausibility. Applicable conditions: Diabetes Mellitus
Since lactulose solution contains galactose and lactose, it should be used cautiously in patients with diabetes.
References (4)
- (2002) "Product Information. Chronulac (lactulose)." Hoechst Marion Roussel
- (2002) "Product Information. Cephulac (lactulose)." Hoechst Marion Roussel
- (2001) "Product Information. Duphalac (lactulose)." Solvay Pharmaceuticals Inc
- (2012) "Product Information. Enulose (lactulose)." United Research Laboratories/Mutual Pharmaceutical Company
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Lactulose drug interactions
There are 249 drug interactions with lactulose.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Linzess
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Xifaxan
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Dulcolax
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Metamucil
Metamucil is used for constipation, dietary fiber supplementation, irritable bowel syndrome
GoLYTELY
GoLYTELY is used for bowel preparation, constipation, chronic, gastrointestinal decontamination
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.