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Fenoldopam Disease Interactions

There are 5 disease interactions with fenoldopam.

Major

Fenoldopam (applies to fenoldopam) congestive heart failure

Major Potential Hazard, High plausibility.

Fenoldopam causes a dose-related fall in blood pressure that may worsen congestive heart failure. Therapy with fenoldopam should be administered cautiously in patients with heart failure. Monitoring blood pressure at regular intervals is recommended.

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Major

Fenoldopam (applies to fenoldopam) glaucoma

Major Potential Hazard, High plausibility. Applicable conditions: Glaucoma/Intraocular Hypertension

Fenoldopam causes a dose-dependent increase in intraocular pressure. Therapy with fenoldopam should be administered cautiously in patients with glaucoma or intraocular hypertension. Intraocular pressure may return to baseline in 2 hours following discontinuation of fenoldopam.

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Major

Fenoldopam (applies to fenoldopam) hypokalemia

Major Potential Hazard, High plausibility.

The use of fenoldopam is associated with hypokalemia (less than 3 mEq/L after 6 hours of infusion). Therapy with fenoldopam should be administered cautiously in patients with preexisting hypokalemia. Monitoring serum electrolytes and potassium replacement as required is recommended.

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Major

Fenoldopam (applies to fenoldopam) hypotension

Major Potential Hazard, High plausibility. Applicable conditions: Cerebral Vascular Disorder

Fenoldopam may cause symptomatic hypotension that may exacerbate cerebral infarction or hemorrhage. Monitoring blood pressure closely during administration is recommended.

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Major

Fenoldopam (applies to fenoldopam) tachycardia

Major Potential Hazard, Moderate plausibility. Applicable conditions: Tachyarrhythmia

The use of fenoldopam is associated with producing dose-related compensatory tachycardia, particularly with infusion rates greater than 0.1 mcg/kg/min in adults and >0.8 mcg/kg/min in pediatric patients. Tachycardia may diminish over time, but remains substantial at higher doses. Care should be exercised when using this agent in patients at risk.

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Fenoldopam drug interactions

There are 265 drug interactions with fenoldopam.

Fenoldopam alcohol/food interactions

There is 1 alcohol/food interaction with fenoldopam.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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