Doxepin topical Disease Interactions
There are 2 disease interactions with doxepin topical.
Doxepin topical (applies to doxepin topical) anticholinergic effects
Moderate Potential Hazard, High plausibility. Applicable conditions: Glaucoma/Intraocular Hypertension, Urinary Retention, Gastrointestinal Obstruction, Dementia
Doxepin possesses anticholinergic activity and is systemically absorbed when applied topically. Therapy with doxepin should be administered cautiously in patients with conditions adversely affected by anticholinergic activity, such as urinary retention, angle-closure glaucoma or elevated intraocular pressure, gastrointestinal obstructive disorders, or dementia.
Doxepin topical (applies to doxepin topical) renal/hepatic dysfunction
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction, Liver Disease
Doxepin topical is systemically absorbed and metabolized by the liver to an active form. Parent drug and metabolites are eliminated by the kidney. Renal and hepatic impairment alter the metabolism and elimination of doxepin and/or its metabolites.
Switch to professional interaction data
Doxepin topical drug interactions
There are 589 drug interactions with doxepin topical.
Doxepin topical alcohol/food interactions
There is 1 alcohol/food interaction with doxepin topical.
Report options
More about doxepin topical
- doxepin topical consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (4)
- Side effects
- Dosage information
- During pregnancy
- Drug class: topical antihistamines
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Benadryl
Benadryl is an antihistamine and is used to treat sneezing, runny nose, itching and other ...
Atarax
Atarax (hydroxyzine) is used to treat anxiety disorders and allergic skin conditions. Inludes ...
Dupixent
Dupixent is used to treat eczema, eosinophilic or oral-corticosteroid-dependent asthma, chronic ...
Vistaril
Vistaril (hydroxyzine) is used as a sedative to treat anxiety and tension and to treat allergic ...
Lidoderm
Lidoderm is a lidocaine patch used to relieve nerve pain after shingles by numbing the skin and ...
Cyproheptadine
Cyproheptadine systemic is used for allergic reactions, allergic rhinitis, allergies, anorexia ...
Hydrocortisone topical
Hydrocortisone cream is used to treat eczema, dermatitis, psoriasis, hemorrhoids, insect bites or ...
Lidocaine topical
Lidocaine topical is used for anal itching, anesthesia, burns, external, gastrointestinal surgery ...
Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Triamcinolone
Triamcinolone is used to treat allergies, skin conditions, ulcerative colitis, and arthritis. Learn ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.