Skip to main content

Daridorexant Disease Interactions

There are 5 disease interactions with daridorexant.

Major

Daridorexant (applies to daridorexant) narcolepsy

Major Potential Hazard, Moderate plausibility.

Daridorexant is contraindicated in patients with narcolepsy.

Switch to professional interaction data

Moderate

Daridorexant (applies to daridorexant) alcohol/drug abuse

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Alcoholism, Drug Abuse/Dependence

Patients with a history of abuse or addiction to alcohol or other substances may be at increased risk for abuse of or addiction to daridorexant and should be monitored closely.

Switch to professional interaction data

Moderate

Daridorexant (applies to daridorexant) COPD/pulmonary impairment

Moderate Potential Hazard, Moderate plausibility.

Daridorexant is a respiratory depressant and should be used with caution if prescribed to patients with impaired respiratory function. This drug has not been studied in patients with moderate to severe sleep apnea requiring CPAP or in patients with severe chronic obstructive pulmonary disease (COPD).

Switch to professional interaction data

Moderate

Daridorexant (applies to daridorexant) depression/suicidal ideation

Moderate Potential Hazard, Moderate plausibility.

Daridorexant can worsen depression and suicidal thoughts and actions and should be used with caution in patients with depression. These patients should be monitored closely and any preventive measures should be taken.

Switch to professional interaction data

Moderate

Daridorexant (applies to daridorexant) hepatic dysfunction

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Daridorexant is not recommended in patients with severe hepatic dysfunction. The maximum recommended dosage in patients with moderate hepatic dysfunction is 25 mg once per night.

Switch to professional interaction data

Daridorexant drug interactions

There are 677 drug interactions with daridorexant.

Daridorexant alcohol/food interactions

There is 1 alcohol/food interaction with daridorexant.

Report options

Loading...
QR code containing a link to this page

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer