Canesten 1 (clotrimazole topical) Disease Interactions
There is 1 disease interaction with Canesten 1 (clotrimazole topical):
Clotrimazole lozenges (applies to Canesten 1) liver impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Abnormal liver function tests have been reported in patients treated with clotrimazole lozenges. Elevated SGOT levels were reported in about 15% of patients in clinical trials. Elevations were usually minimal and difficult to distinguish if caused by clotrimazole, other treatments or underlying disease. Periodic assessment of liver function is recommended, especially in patients with preexisting liver impairment.
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Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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