Otovel (ciprofloxacin / fluocinolone otic) Disease Interactions
There is 1 disease interaction with Otovel (ciprofloxacin / fluocinolone otic):
Otic agents (Includes Otovel) ↔ perforated tympanic membrane
Severe Potential Hazard, High plausibility. Applies to: Perforated Tympanic Membrane, Chronic Otitis Media
The use of medications that are intended for the treatment of otitis externa or other conditions of the external ear canal should generally be avoided, or otherwise approached with caution, in patients with a perforated tympanic membrane due to the risk of toxicity from medication that may get into the middle ear. Caution is also advised in patients with longstanding, chronic otitis media because of the possibility of a perforated tympanic membrane in such patients.
- "Multum Information Services, Inc. Expert Review Panel"
- Behrman R, Kliegman R, Arvin A, Nelson W, eds. "Nelson Textbook of Pediatrics. 15th ed." Philadelphia, PA: W.B. Saunders Company (1996):
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- Drug class: otic steroids with anti-infectives
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Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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