Generic Name: ofloxacin (oh-FLOX-a-sin)
Medically reviewed by Drugs.com. Last updated on Sep 26, 2020.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
Therapeutic Class: Antibacterial
Chemical Class: Fluoroquinolone
Uses for ofloxacin
Ofloxacin belongs to the family of medicines called antibiotics. Ofloxacin otic solution is used to treat infections of the ear canal. It also is used to treat infections of the middle ear in patients with nonintact tympanic membranes (holes or tubes in the eardrums).
Ofloxacin is available only with your doctor's prescription.
Before using ofloxacin
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For ofloxacin, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to ofloxacin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Use is not recommended in infants younger than 1 year of age.
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of otic ofloxacin in the elderly with use in other age groups.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking ofloxacin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using ofloxacin with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using ofloxacin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Aripiprazole Lauroxil
- Arsenic Trioxide
- Cholera Vaccine, Live
- Inotuzumab Ozogamicin
- Insulin Aspart, Recombinant
- Insulin Bovine
- Insulin Degludec
- Insulin Detemir
- Insulin Glargine, Recombinant
- Insulin Glulisine
- Insulin Lispro, Recombinant
- Sodium Phosphate
- Sodium Phosphate, Dibasic
- Sodium Phosphate, Monobasic
Using ofloxacin with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Aminolevulinic Acid
- Lanthanum Carbonate
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Proper use of ofloxacin
Ofloxacin eardrops comes with patient information and instructions (Medication Guide). Be sure to read these instructions before using the eardrops . If you have any questions, check with your doctor or health care professional.
- Hold the bottle in your hands for 1 or 2 minutes to warm up the solution before putting it in your ear. Otherwise, putting cold solution in your ear could cause you to become dizzy.
- Wash your hands with soap and water.
- Gently clean any discharge that can be removed easily from the outer ear, but do not insert any object or swab into the ear canal.
- If you are using the eardrops for a middle ear infection—Drop the medicine into the ear canal. Then, gently press the tragus of the ear (see the diagram in the Medication Guide) four times in a pumping motion. This will allow the drops to pass through the hole or tube in the eardrum and into the middle ear.
- If you are using the eardrops for an ear canal infection—Gently pull the outer ear up and back for adults (down and back for children) to straighten the ear canal. This will allow the eardrops to flow down into the ear canal.
- Keep the ear facing up for about 5 minutes to allow the medicine to come into contact with the infection.
- If both ears are being treated, turn over after 5 minutes, and repeat the application for the other ear.
- To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the ear). Also, keep the container tightly closed.
To help clear up your infection completely, keep using ofloxacin for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses.
The dose of ofloxacin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of ofloxacin. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For eardrops dosage form:
- For ear infections:
- Adults and teenagers (12 years of age and older)—Place 10 drops in each affected ear two times a day for ten to fourteen days, depending on the infection.
- Children 1 to 12 years of age—Place 5 drops in each affected ear two times a day for ten days.
- Children younger than 1 year of age—Use and dose must be determined by your doctor.
- For ear infections:
If you miss a dose of ofloxacin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Precautions while using ofloxacin
If your symptoms do not improve within a few days, or if they become worse, check with your doctor.
Oral and systemic ofloxacin and other similar antibiotics have sometimes caused a severe allergic reaction. It is not known if otic ofloxacin may cause this reaction. However, stop using ofloxacin and check with your doctor immediately if you notice skin rash or itching, shortness of breath, or swelling of the face or neck.
Ofloxacin side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
- Burning, itching, redness, skin rash, swelling, or other sign of irritation not present before use of ofloxacin
Check with your doctor as soon as possible if any of the following side effects occur:
- Bleeding from the ear
- fast heartbeat
- ringing in the ear
- runny or stuffy nose
- sore throat
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Change in taste
- numbness or tingling
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
More about ofloxacin otic
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Compare Alternatives
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- 1 Review
- Drug class: otic anti-infectives
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