dexamethasone (Intraocular route)Pronunciation
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
Therapeutic Class: Corticosteroid, Weak
Pharmacologic Class: Adrenal Glucocorticoid
Uses For dexamethasone
Dexamethasone intravitreal implant is used to treat an eye disease called macular edema (swelling of the back of the eye). Macular edema occurs when a blood vessel in the eye is clogged. This causes vision changes that must be treated right away. Dexamethasone is a corticosteroid (steroid medicine) that helps reduce the swelling in the eye.
Dexamethasone intravitreal implant is also used to treat an eye disease called uveitis (swelling in the middle part of the eye). dexamethasone is also used to treat diabetic macular edema in patients with artificial lens implant or are scheduled for cataract surgery.
dexamethasone is to be given only by or under the supervision of your doctor.
Before Using dexamethasone
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For dexamethasone, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to dexamethasone or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of dexamethasone implant in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of dexamethasone implant in the elderly.
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving dexamethasone, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using dexamethasone with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
- Rotavirus Vaccine, Live
Using dexamethasone with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Doxorubicin Hydrochloride Liposome
- Eslicarbazepine Acetate
- Vincristine Sulfate Liposome
Using dexamethasone with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of dexamethasone. Make sure you tell your doctor if you have any other medical problems, especially:
- Detached retina (eye disorder) or
- Endophthalmitis (inflammation of the eye) or
- Glaucoma (increased pressure in the eye) or
- Herpes infection of the eye, history of—Use with caution. May make these conditions worse.
- Eye infection caused by a virus, fungus, or bacteria or
- Eye lens problems (non-intact posterior lens capsule) or
- Glaucoma, advanced—Should not be used in patients with these conditions.
Proper Use of dexamethasone
dexamethasone is an implant that is placed in your eye. It will stay in your eye and does not need to be removed. An eye doctor will give you dexamethasone in a hospital or clinic setting.
Precautions While Using dexamethasone
Your eye doctor will want to check your progress at regular visits, especially during the first few weeks after you receive dexamethasone.
Serious eye problems may occur after receiving dexamethasone. Check with your eye doctor right away if you have a change in vision or the eye becomes red, sensitive to light, or painful. Also, tell your doctor if you feel increased pressure in the eye.
dexamethasone may cause temporary blurred vision. Avoid driving, using machines, or doing anything else that could be dangerous if you are not able to see well.
This implant could move into a different part of your eye if the back part of your lens is missing or torn. Talk to your doctor if you have concerns.
dexamethasone Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:More common
- Bloody eye
- blurred vision
- change in vision
- eye pain
- loss of vision
- redness of the white part of the eye or inside of the eyelid
- decreased vision
- gradual loss of vision
- seeing a veil or curtain across part of your vision
- seeing flashes or sparks of light
- seeing floating spots before the eyes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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