Comparing Topiramate vs Lyrica
Topiramate | Lyrica |
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Topiramate | Lyrica (pregabalin) |
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Prescription only
Topiramate may be prescribed either alone or in combination with other medications for the treatment of certain types of epilepsy, or it may be given for the prevention of migraines. Drowsiness is a... View more |
Prescription only
Lyrica can help relieve nerve pain and control seizures but it is likely to cause drowsiness. Prescribed for Neuropathic Pain, Fibromyalgia, Diabetic Peripheral Neuropathy, Neuralgia, Postherpetic... View more |
Related suggestions Fibromyalgia
Diabetic Peripheral Neuropathy
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More about Topiramate | More about Lyrica (pregabalin) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Topiramate has an average rating of 6.3 out of 10 from a total of 1326 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 29% reported a negative effect. |
Lyrica has an average rating of 6.4 out of 10 from a total of 927 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 27% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: topiramate side effects in more detail. |
See also: Lyrica side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all topiramate prices |
View all Lyrica prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Eprontia, Qudexy XR, Topamax, Trokendi XR | Other pregabalin brands include: Lyrica CR | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
56 hours |
6.3 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
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Pregnancy Category | |||||||||||||||||
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 288 drugs are known to interact with topiramate:
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A total of 283 drugs are known to interact with Lyrica:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
December 24, 1996 |
December 30, 2004 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.