Comparing Tacrolimus Topical vs Zoryve
| Tacrolimus topical | Zoryve (roflumilast) |
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| Tacrolimus topical | Zoryve (roflumilast) |
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Prescription only
Prescribed for Lichen Planopilaris, Atopic Dermatitis, Perioral Dermatitis, Psoriasis, Seborrheic Dermatitis. Tacrolimus topical may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Plaque Psoriasis. Zoryve may also be used for purposes not listed in this medication guide. |
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| More about Tacrolimus topical | More about Zoryve (roflumilast) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Tacrolimus topical has an average rating of 6.7 out of 10 from a total of 156 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 27% reported a negative effect. |
Zoryve has an average rating of 8.6 out of 10 from a total of 48 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Tacrolimus topical side effects |
View all Zoryve side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Tacrolimus topical prices |
View all Zoryve prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Protopic, Tacrus | Other roflumilast brands include: Zoryve Foam | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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21.2 hours |
9.6 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 1 drugs are known to interact with Tacrolimus topical:
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A total of 103 drugs are known to interact with Zoryve:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | |||||||||||||||||
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December 08, 2000 |
July 29, 2022 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.