Comparing Onglyza vs Tradjenta

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Onglyza (saxagliptin)	Tradjenta (linagliptin)	Enter another drug to compare

Onglyza (saxagliptin)

Tradjenta (linagliptin)

Prescription only

Prescribed for Type 2 Diabetes. Onglyza may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Type 2 Diabetes. Tradjenta may also be used for purposes not listed in this medication guide.

More about Onglyza (saxagliptin)

More about Tradjenta (linagliptin)

Ratings & Reviews

Onglyza has an average rating of 5.9 out of 10 from a total of 15 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 33% reported a negative effect.

Tradjenta has an average rating of 3.5 out of 10 from a total of 74 ratings on Drugs.com. 22% of reviewers reported a positive effect, while 69% reported a negative effect.

View all 15 reviews

View all 74 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Onglyza side effects

Joint pain (14.9%)
Back pain (13.5%)
Dizziness (10.8%)
Headaches (9.5%)
Stomach pain (9.5%)
Tiredness (8.1%)
Weight gain (8.1%)

View all Tradjenta side effects

Drug Class

Dipeptidyl peptidase 4 inhibitors

Dipeptidyl peptidase 4 inhibitors

Generic Availability

Lower cost generic approved

Pricing and Coupons * Prices are without insurance

Quantity	90 tablet
Strength	5 mg
Per unit^*	$17.37
Cost^*	$1,563.45

View all Onglyza prices

Quantity	100 each
Strength	5 mg
Per unit^*	$18.78
Cost^*	$1,878.45

View all Tradjenta prices

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Dosage Forms

Oral tablet

Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

3.1 hours

12 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full pregnancy warnings document.

Category B No proven risk in humans

See the full pregnancy warnings document.

Drug Interactions

A total of 417 drugs are known to interact with Onglyza:

2 major drug interactions (5 brand and generic names)
411 moderate drug interactions (1856 brand and generic names)
4 minor drug interactions (16 brand and generic names)

A total of 350 drugs are known to interact with Tradjenta:

2 major drug interactions (5 brand and generic names)
347 moderate drug interactions (1657 brand and generic names)
1 minor drug interactions (10 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more

Disease Interactions

Pancreatitis

First Approval Date

July 31, 2009

May 02, 2011

WADA Class View classifications

N/A

More Information

Patient Resources

Onglyza uses

Tradjenta uses

Professional Resources

Prescribing information

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Onglyza vs Tradjenta

See also:

Trulicity

Lantus

Ozempic

Tresiba

Levemir

Victoza

Novolog

Basaglar

Soliqua

Toujeo SoloStar

Further information

Comparing Onglyza vs Tradjenta

See also:

Further information

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