Comparing Nextstellis vs Safyral
| Nextstellis (drospirenone / estetrol) | Safyral (drospirenone / ethinyl estradiol / levomefolate calcium) |
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| Nextstellis (drospirenone / estetrol) | Safyral (drospirenone / ethinyl estradiol / levomefolate calcium) |
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Prescription only
Prescribed for Birth Control. Nextstellis may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Birth Control. Safyral may also be used for purposes not listed in this medication guide. |
Related suggestions Birth Control
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| More about Nextstellis (drospirenone / estetrol) | More about Safyral (drospirenone / ethinyl estradiol / levomefolate calcium) | |
| Ratings & Reviews | ||
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Nextstellis has an average rating of 6.8 out of 10 from a total of 29 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 14% reported a negative effect. |
Safyral has an average rating of 5.9 out of 10 from a total of 67 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 25% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||
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View all Nextstellis side effects |
View all Safyral side effects |
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| Drug Class | ||
| Generic Availability | ||
| Pricing and Coupons * Prices are without insurance | ||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | ||
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| Brand Names | ||
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N/A |
Other drospirenone / ethinyl estradiol / levomefolate calcium brands include: Beyaz, Tydemy | |
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||
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32.5 hours (empirically) |
30 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||
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Summary unavailable. See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||
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A total of 526 drugs are known to interact with Nextstellis:
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A total of 605 drugs are known to interact with Safyral:
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| Alcohol/Food/Lifestyle Interactions | ||
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| Disease Interactions | ||
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| First Approval Date | ||
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April 15, 2021 |
December 16, 2010 |
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| WADA Class View classifications | ||
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N/A |
N/A |
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| More Information | ||
| Patient Resources | ||
| Professional Resources | ||
| Related Treatment Guide | ||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.