Comparing Imbruvica vs Leukeran
| Imbruvica Remove Imbruvica from your drug comparison | Leukeran Remove Leukeran from your drug comparison |
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| Imbruvica ibrutinib Remove Imbruvica from your drug comparison | Leukeran chlorambucil Remove Leukeran from your drug comparison | ||||||||||||||||
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Imbruvica is an oral tablet that may be taken once daily to treat certain types of cancers. It works by inhibiting the enzyme Bruton tyrosine kinase (BTK) which is part of a crucial signaling... View more |
Prescribed for Chronic Lymphocytic Leukemia, Cancer, Hodgkin's Lymphoma, Lymphoma. Leukeran may also be used for purposes not listed in this medication guide. |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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5.8
For Chronic Lymphocytic Leukemia: Due to my having a variant GI system (with its own side-effects), my oncologist, in an abundance of caution, started me on Imbruvica 1 capsule in the AM, daily. Literally within days, the SIGNIFICANTLY large lymphs in the front and rear of my neck, disappeared. WOW! MY WBC's skyrocketed, but that is typically expected due to the mechanisms by which Imbruvica works. Oversimplifying here -- the abnormal (cancerous) cells, congregate in the lymphs. Imbruvica forces those abnormal cells out into the bloodstream, where they can be attacked and starved of the BTK protein, which they need to thrive and propagate. The "dead" abnormal cells are then flushed out of the body. After 2 months dose upped to 2 capsules daily, and still tolerating well. |
8.7
For Chronic Lymphocytic Leukemia: Took 6 months to bring my count down from 149,000 For Chronic Lymphocytic Leukemia: I have been taking Leukeran since 11-19-2002 with no side effects, to treat CLL. Currently I am taking 2mg three times per week. My white count is staying under 19K. I have no symptoms of the CLL. The alternative is chemotherapy, and I said no way. Leukeran is keeping my Leukemia in check. |
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Drug Class |
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Side Effects |
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Common side effects include: infection, anemia, neutropenia, thrombocytopenia, bruise, and cytopenia. See the full Imbruvica side effects document. |
See the full Leukeran side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Imbruvica prices |
View all Leukeran prices |
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Generic Availability |
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No |
No |
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Dosage Form(s) Available |
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Brand Names |
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N/A |
N/A |
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Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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6 hours |
2 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
N/A |
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Drug Interactions |
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A total of 368 drugs are known to interact with Imbruvica:
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A total of 190 drugs are known to interact with Leukeran:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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November 13, 2013 |
March 18, 1957 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Chronic Lymphocytic Leukemia: I've been on Imbruvica for only 6 weeks because of bad side effects my doctor stopped the medication. Since I started taking the medication in October 2019 and now is October 2020 still have the diarrhea. I tried all medications and some teas to stopped it. Really don't know what to do.