Comparing Hydrochlorothiazide vs Metolazone
| Hydrochlorothiazide | Metolazone |
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| Hydrochlorothiazide | Metolazone |
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Prescription only
Hydrochlorothiazide (HCTZ) may be used to relieve edema (fluid retention) and to lower high blood pressure. A headache, dizziness on standing, dehydration, skin reactions, and depletion of... View more |
Prescription only
Prescribed for Edema, High Blood Pressure. Metolazone may also be used for purposes not listed in this medication guide. |
Related suggestions High Blood Pressure (Hypertension)
Popular comparisons
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| More about Hydrochlorothiazide | More about Metolazone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Hydrochlorothiazide has an average rating of 5.2 out of 10 from a total of 185 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 38% reported a negative effect. |
Metolazone has an average rating of 7.8 out of 10 from a total of 6 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Hydrochlorothiazide side effects |
View all Metolazone side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Hydrochlorothiazide prices |
View all Metolazone prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Aquazide H, Carozide, Diaqua, Esidrix, Ezide, Hydro Par, Inzirqo, Microzide | Zaroxolyn | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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12 hours |
20 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 472 drugs are known to interact with Hydrochlorothiazide:
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A total of 467 drugs are known to interact with Metolazone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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February 12, 1959 |
November 27, 1973 |
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| WADA Class View classifications | |||||||||||||||||
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| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.