Metolazone use while Breastfeeding
Drugs containing Metolazone: Zaroxolyn, Mykrox
Medically reviewed on Mar 12, 2018
Metolazone Levels and Effects while Breastfeeding
Summary of Use during Lactation
If metolazone is required by the mother, it is not a reason to discontinue breastfeeding. Intense diuresis with large doses may decrease breastmilk production.
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information on metolazone was not found as of the revision date. Intense diuresis with thiazides and thiazide-like diuretics, fluid restriction and breast binding have been used to suppress postpartum lactation. The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of diuretics on established, ongoing lactation.
Alternate Drugs to Consider
1. Healy M. Suppressing lactation with oral diuretics. Lancet. 1961;277:1353-4.
2. Reiher KH. [Suppression of lactation by stimulation of diuresis]. Zentralbl Gynakol. 1963;85:188-90. PMID: 13973786
3. Stout G. Suppression of lactation. Br Med J. 1962;1:1150. Letter. PMC: PMC1958377
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LactMed Record Number
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