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Epidiolex Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Epidiolex Onfi Banzel
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Epidiolex (cannabidiol) Onfi (clobazam) Banzel (rufinamide)
Prescription only

Prescribed for Lennox-Gastaut Syndrome, Dravet Syndrome, Tuberous Sclerosis Complex. Epidiolex may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Lennox-Gastaut Syndrome. Onfi may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Lennox-Gastaut Syndrome. Banzel may also be used for purposes not listed in this medication guide.

Related suggestions

Lennox-Gastaut Syndrome
Popular comparisons
More about Epidiolex (cannabidiol) More about Onfi (clobazam) More about Banzel (rufinamide)
Ratings & Reviews

Epidiolex has an average rating of 3.7 out of 10 from a total of 3 ratings on Drugs.com. 0% of reviewers reported a positive effect, while 67% reported a negative effect.

Onfi has an average rating of 5.0 out of 10 from a total of 11 ratings on Drugs.com. 27% of reviewers reported a positive effect, while 36% reported a negative effect.

Banzel has an average rating of 9.4 out of 10 from a total of 7 ratings on Drugs.com. 86% of reviewers reported a positive effect, while 0% reported a negative effect.

View all 3 reviews

View all 11 reviews

View all 7 reviews

Drug Class
Side Effects

See also: Epidiolex side effects in more detail.

See also: Onfi side effects in more detail.

See also: Banzel side effects in more detail.
Generic Availability

No lower cost generic approved

Lower cost generic approved

Lower cost generic approved
Pricing and Coupons * Prices are without insurance
Quantity 60 mL
Dosage 100 mg/mL
Per Unit* $17.37
Cost* $1,042.49

View all Epidiolex prices

Quantity 100 tablet
Dosage 10 mg
Per Unit* $31.49
Cost* $3,149.13

View all Onfi prices

Quantity 460 mL
Dosage 40 mg/mL
Per Unit* $4.05
Cost* $1,861.73

View all Banzel prices

Get free Discount Card

Get free Discount Card

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Dosage Forms Available
  • Oral liquid
  • Oral suspension
  • Oral tablet
  • Oral suspension
  • Oral tablet
Brand Names

N/A

 Other clobazam brands include: Sympazan

N/A
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

61 hours

82 hours

10 hours
CSA Schedule ** View glossary of terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
4
Some potential for abuse

Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category

Summary unavailable.

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
Drug Interactions

A total of 606 drugs are known to interact with Epidiolex:

  • 17 major drug interactions (72 brand and generic names)
  • 536 moderate drug interactions (2337 brand and generic names)
  • 53 minor drug interactions (177 brand and generic names)

A total of 514 drugs are known to interact with Onfi:

  • 33 major drug interactions (165 brand and generic names)
  • 447 moderate drug interactions (1734 brand and generic names)
  • 34 minor drug interactions (221 brand and generic names)

A total of 495 drugs are known to interact with Banzel:

  • 8 major drug interactions (25 brand and generic names)
  • 470 moderate drug interactions (2548 brand and generic names)
  • 17 minor drug interactions (60 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Food may affect the absorption and blood levels of cannabidiol. To avoid significant fluctuations... View more
  • Using cannabidiol together with alcohol may increase side effects such as dizziness, drowsiness... View more
  • Alcohol can increase the nervous system side effects of cloBAZam such as dizziness, drowsiness, and... View more
  • Food can enhance the levels of rufinamide in your body. To ensure maximal oral absorption... View more
Disease Interactions
First Approval Date

N/A

N/A

November 14, 2008
WADA Class View World Anti-Doping Agency classifications.

N/A

N/A

N/A
More Information
Patient resources
Professional Resources
Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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