Comparing Ephedrine vs Modafinil

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Ephedrine

Modafinil

Prescription and OTC

Prescribed for Myasthenia Gravis, Narcolepsy, COPD - Acute, Asthma - acute, Hypotension, Adams-Stokes Syndrome. Ephedrine may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Chronic Fatigue Syndrome, ADHD, Depression, Fatigue, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, Shift Work Sleep Disorder, Idiopathic Hypersomnia. Modafinil may also be... View more

More about Ephedrine

More about Modafinil

Ratings & Reviews

Ephedrine has an average rating of 8.2 out of 10 from a total of 9 ratings on Drugs.com. 78% of reviewers reported a positive effect, while 11% reported a negative effect.

Modafinil has an average rating of 7.3 out of 10 from a total of 536 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 18% reported a negative effect.

View all 9 reviews

View all 536 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Ephedrine side effects

Headaches (11.0%)
Anxiety (8.0%)
Tiredness (5.2%)
Depression (3.9%)
Fatigue (3.9%)
Insomnia (3.5%)
Nausea (3.5%)

View all Modafinil side effects

Drug Class

CNS stimulants

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	10 mL
Strength	50 mg/mL
Per unit^*	$10.11 - $42.64
Cost^*	$101.06 - $426.37

View all Ephedrine prices

Quantity	20 each
Strength	200 mg
Per unit^*	$14.47
Cost^*	$289.33

View all Modafinil prices

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Dosage Forms

Injectable solution
Intravenous solution

Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

11 hours

15 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Some potential for abuse

Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 233 drugs are known to interact with Ephedrine:

33 major drug interactions (130 brand and generic names)
186 moderate drug interactions (759 brand and generic names)
14 minor drug interactions (167 brand and generic names)

A total of 521 drugs are known to interact with Modafinil:

76 major drug interactions (183 brand and generic names)
265 moderate drug interactions (1054 brand and generic names)
180 minor drug interactions (789 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

N/A

December 24, 1998

WADA Class View classifications

S6 - Stimulants

S6 - Stimulants

More Information

Patient Resources

Ephedrine uses

Modafinil uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Ephedrine vs Modafinil

See also:

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Ventolin HFA

Rystiggo

Ventolin

Decadron

ProAir HFA

Xopenex

Medrol Dosepak

EpiPen

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Further information

Comparing Ephedrine vs Modafinil

See also:

Further information

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