Cisplatin Alternatives Compared
| Cisplatin | Opdivo | Rybrevant |
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| Cisplatin | Opdivo (nivolumab) | Rybrevant (amivantamab) |
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Prescription only
Prescribed for Bladder Cancer, Anal Cancer, Bone Marrow Transplantation, Blood Cell Transplantation, Brain Tumor, Cervical Cancer, Nasopharyngeal Carcinoma, Neuroblastoma, Non Small Cell Lung Cancer... View more |
Prescription only
Opdivo is an immune checkpoint inhibitor that may be used to treat many different cancers including melanoma, bladder cancer, liver cancer, and lung cancer. Fatigue, skin conditions, a cough, upper... View more |
Prescription only
Prescribed for Non Small Cell Lung Cancer. Rybrevant may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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| More about Cisplatin | More about Opdivo (nivolumab) | More about Rybrevant (amivantamab) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Cisplatin has an average rating of 9.0 out of 10 from a total of 1 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Opdivo has an average rating of 5.3 out of 10 from a total of 87 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 47% reported a negative effect. |
Rybrevant has an average rating of 9.0 out of 10 from a total of 2 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See also: cisplatin side effects in more detail. |
See also: Opdivo side effects in more detail. |
See also: Rybrevant side effects in more detail. |
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| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
N/A |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all cisplatin prices |
View all Opdivo prices |
View all Rybrevant prices |
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| Dosage Forms Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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73 hours |
640.8 hours |
271.2 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 435 drugs are known to interact with cisplatin:
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A total of 16 drugs are known to interact with Opdivo:
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A total of 3 drugs are known to interact with Rybrevant:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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December 19, 1978 |
December 22, 2014 |
May 21, 2021 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.