Comparing Capecitabine vs Oxaliplatin
Capecitabine Remove Capecitabine from your drug comparison | Oxaliplatin Remove Oxaliplatin from your drug comparison |
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Capecitabine Remove Capecitabine from your drug comparison | Oxaliplatin Remove Oxaliplatin from your drug comparison | ||||||||||||||||
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Prescribed for Colorectal Cancer, Breast Cancer - Metastatic, Breast Cancer, Anal Cancer. May also be prescribed off label for Non-Small Cell Lung Cancer, Pancreatic Cancer, Prostate Cancer, Renal... View more |
Prescribed for Colorectal Cancer. oxaliplatin may also be used for purposes not listed in this medication guide. |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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7.0
For Colorectal Cancer: My mum was on this medication for approximately 12 months. Compared to the Folfox-4 protocol, this medication delivers the same effectiveness with significantly less side effects in addition to the convenience of being in tablet form. The only side effect that caused mum to discontinue the treatment was decreased white blood count causing reduced immunity (similar to other protocols). |
6.0
For Colorectal Cancer: I had stage 2 colon cancer with golf ball cancer & micro-invasion of colon wall. Lymph nodes negative. Given 5-FU and Oxaliplatin. Told entire time creatinine and bilirubin good - looking back now 2.5 yrs later I have stage 3 kidney disease. No one ever mentioned GFR. If no one says anything about it to you, make sure you ask. I have yet to determine if my GFR was low prior to chemo, or what decision I would have made about Oxaliplatin but I should have been informed. When asked physician I was always told - it is all good. Had neuropathy too but that's ok.,. I am still cancer free and Praise God. For Colorectal Cancer: This is an extremely potent medication when used in combination with 5-Fluorouracil. My mum had a stage IV colorectal cancer which has metastasised into the soft tissue of the lower abdomen causing an ugly skin lesions on the abdomen. After just three cycles of Oxiplatin and 5-FU the lesion completely healed and mum had a substantial reduction in the tumour size and progression rate. The problem with the treatment is the severe side effects mainly reduced white blood count. |
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Drug Class |
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Side Effects |
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Commonly reported side effects include: anemia, diarrhea, hyperbilirubinemia, increased serum alkaline phosphatase, increased serum transaminases, nausea, neutropenia, palmar-plantar erythrodysesthesia, paresthesia, stomatitis, thrombocytopenia, and vomiting. See the full capecitabine side effects document. |
Commonly reported side effects include: peripheral neuropathy, and severe peripheral neuropathy. See the full oxaliplatin side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all capecitabine prices |
View all oxaliplatin prices |
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Generic Availability |
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Yes (this medicine) |
Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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Xeloda | Eloxatin | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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0.75 hours |
391 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
N/A |
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Drug Interactions |
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A total of 210 drugs are known to interact with capecitabine:
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A total of 522 drugs are known to interact with oxaliplatin:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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April 30, 1998 |
N/A |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Colorectal Cancer: Only on my 3rd week of this medicine but finding it far less intrusive than the Folfox (5FU) treatment I had 4 years ago via drip and permanent line, with a pump for 48 hours each treatment. Some thinning of hair, not really noticeable, and lots of my friends have less hair than me anyway! I'm a keen runner and cyclist, and do find that I can't push myself as hard anymore, get very short of breath on up-hills. But at least I'm still able to lead an active lifestyle, hill walking causes no trouble at all. Feel slightly nauseous quite frequently, but not been sick yet, and brush my teeth half a dozen times a day to ensure no soreness (which I had with 5FU). Slight soreness on soles of feet, particularly after long runs or walks.