Comparing Aubagio vs Ocrevus

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Aubagio teriflunomide

Ocrevus ocrelizumab

Aubagio is a selective immunosuppressant that may be used in the treatment of multiple sclerosis. It interacts with many other medications and carries a boxed warning about the risk of liver toxicity... View more

Ocrevus is a CD20 monoclonal antibody that causes B-cells to self-destruct or disintegrate, reducing inflammation in people with MS. After an initial loading dose, it is given by IV infusion every... View more

Prescription only

Ratings & Reviews

View all 72 reviews

View all 117 reviews

Drug Class

Selective immunosuppressants

CD20 monoclonal antibodies

Side Effects

Common side effects include: alopecia, decreased neutrophils, decreased white blood cell count, diarrhea, increased serum alanine aminotransferase, nausea, decreased platelet count, hyperkalemia, and lymphocytopenia.

See the full Aubagio side effects document.

Common side effects include: lower respiratory tract infection, upper respiratory tract infection, cough, and infusion related reaction.

See the full Ocrevus side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	28 each
Dosage	7 mg
Per Unit^*	$280.80
Cost^*	$7,862.40

View all Aubagio prices

Quantity	10 mL
Dosage	300 mg/10 mL
Per Unit^*	$1,778.93
Cost^*	$17,789.25

View all Ocrevus prices

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Generic Availability

Dosage Form(s) Available

Oral tablet

Intravenous solution

Brand Names

N/A

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

456 hours

624 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category X Not for use in pregnancy

See the full Pregnancy Warnings document.

Summary unavailable.

See the full Pregnancy Warnings document.

Drug Interactions

A total of 620 drugs are known to interact with Aubagio:

467 major drug interactions (1877 brand and generic names)
144 moderate drug interactions (576 brand and generic names)
9 minor drug interactions (50 brand and generic names)

A total of 331 drugs are known to interact with Ocrevus:

33 major drug interactions (86 brand and generic names)
291 moderate drug interactions (887 brand and generic names)
7 minor drug interactions (33 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Teriflunomide may cause liver problems, and using it with other medications that can also affect... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

September 12, 2012

March 28, 2017

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer