Comparing Amitriptyline vs Lidocaine
Amitriptyline | Lidocaine |
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Amitriptyline | Lidocaine |
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Prescription only
Amitriptyline is an effective antidepressant but it may cause drowsiness initially and a withdrawal syndrome with abrupt discontinuation. It may be used off-label to treat other conditions such as... View more |
Prescription only
Lidocaine is used as a local or regional anesthetic to prevent pain signals from being transmitted to the brain during surgical, dental, and other procedures. Lidocaine antiarrhythmic is used in the... View more |
Related suggestions Burning Mouth Syndrome (Glossopyrosis)
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More about Amitriptyline | More about Lidocaine | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Amitriptyline has an average rating of 7.6 out of 10 from a total of 1767 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 16% reported a negative effect. |
Lidocaine has an average rating of 5.4 out of 10 from a total of 21 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 47% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: amitriptyline side effects in more detail. |
See also: lidocaine side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all amitriptyline prices |
View all lidocaine prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
N/A |
Anestacaine, DentiPatch, Dilocaine, Xylocaine HCl, Xylocaine-MPF | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
16 hours |
2 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 705 drugs are known to interact with amitriptyline:
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A total of 543 drugs are known to interact with lidocaine:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
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First Approval Date | |||||||||||||||||
April 07, 1961 |
N/A |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.