Comparing Adempas vs Opsumit
| Adempas (riociguat) | Opsumit (macitentan) |
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| Adempas (riociguat) | Opsumit (macitentan) |
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Prescription only
Prescribed for Pulmonary Arterial Hypertension. Adempas may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Pulmonary Arterial Hypertension. Opsumit may also be used for purposes not listed in this medication guide. |
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| More about Adempas (riociguat) | More about Opsumit (macitentan) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Adempas has an average rating of 5.3 out of 10 from a total of 4 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 50% reported a negative effect. |
Opsumit has an average rating of 8.2 out of 10 from a total of 10 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Adempas side effects |
View all Opsumit side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Adempas prices |
View all Opsumit prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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12 hours |
48 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 351 drugs are known to interact with Adempas:
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A total of 210 drugs are known to interact with Opsumit:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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October 08, 2013 |
October 18, 2013 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
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N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.