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Acetaminophen / caffeine / pyrilamine Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Acetaminophen / caffeine / pyrilamine Pamprin Multi-Symptom Menstrual Relief Midol
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Acetaminophen / caffeine / pyrilamine Pamprin Multi-Symptom Menstrual Relief (acetaminophen / pamabrom / pyrilamine) Midol (acetaminophen / pamabrom)
Over-the-counter

Prescribed for Premenstrual Dysphoric Disorder, Premenstrual Syndrome. acetaminophen / caffeine / pyrilamine may also be used for purposes not listed in this medication guide.

Over-the-counter

Prescribed for Premenstrual Dysphoric Disorder, Premenstrual Syndrome. Pamprin Multi-Symptom Menstrual Relief may also be used for purposes not listed in this medication guide.

Over-the-counter

Prescribed for Premenstrual Syndrome. Midol may also be used for purposes not listed in this medication guide.

More about Acetaminophen / caffeine / pyrilamine More about Pamprin Multi-Symptom Menstrual Relief (acetaminophen / pamabrom / pyrilamine) More about Midol (acetaminophen / pamabrom)
Ratings & Reviews

Acetaminophen / caffeine / pyrilamine has an average rating of 8.0 out of 10 from a total of 4 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 0% reported a negative effect.

Pamprin Multi-Symptom Menstrual Relief has an average rating of 10.0 out of 10 from a total of 2 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect.

Midol has an average rating of 7.0 out of 10 from a total of 6 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 17% reported a negative effect.

View all 4 reviews

View all 2 reviews

View all 6 reviews

Drug Class
Side Effects

See also: acetaminophen / caffeine / pyrilamine side effects in more detail.

See also: Pamprin Multi-Symptom Menstrual Relief side effects in more detail.

See also: Midol side effects in more detail.
Generic Availability

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Pricing and Coupons * Prices are without insurance

We could not find an exact match for this medicine. Try searching the Price Guide directly.

We could not find an exact match for this medicine. Try searching the Price Guide directly.

We could not find an exact match for this medicine. Try searching the Price Guide directly.

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Dosage Forms Available

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  • Oral tablet

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Brand Names
Menstrual Relief, Menstrual Relief Extra Strength, Menstrual Relief Maximum Strength, Midol Complete Other acetaminophen / pamabrom / pyrilamine brands include: Menstrual Pain Relief, Menstrual PMS, Menstrual Relief Multi-Symptom, Midol PMS Maximum Strength, Pamprin Maximum Pain, PMS Formula Multi-Symptom, PMS Relief, Premsyn PMS, Syncol View more Other acetaminophen / pamabrom brands include: Backaid Max, Cramp Tabs, Midol Teen, PainAid Premenstrual Formula, Panadol Menstrual Relief, Tylenol Women's Menstrual Relief
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

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CSA Schedule ** View glossary of terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
N
Category N Not classified
N
Category N Not classified
N
Category N Not classified
Drug Interactions

A total of 580 drugs are known to interact with acetaminophen / caffeine / pyrilamine:

  • 22 major drug interactions (103 brand and generic names)
  • 536 moderate drug interactions (2267 brand and generic names)
  • 22 minor drug interactions (145 brand and generic names)

A total of 509 drugs are known to interact with Pamprin Multi-Symptom Menstrual Relief:

  • 19 major drug interactions (100 brand and generic names)
  • 476 moderate drug interactions (1907 brand and generic names)
  • 14 minor drug interactions (54 brand and generic names)

A total of 148 drugs are known to interact with Midol:

  • 9 major drug interactions (28 brand and generic names)
  • 104 moderate drug interactions (321 brand and generic names)
  • 35 minor drug interactions (160 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Alcohol can increase the nervous system side effects of pyrilamine such as dizziness, drowsiness... View more
  • Alcohol can increase the nervous system side effects of pyrilamine such as dizziness, drowsiness... View more
  • Ask your doctor before using acetaminophen together with alcohol. This can cause serious side... View more
Disease Interactions
First Approval Date

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WADA Class View World Anti-Doping Agency classifications.

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More Information
Patient resources
Professional Resources

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Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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