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Trimethoprim and Nausea: What Users Say (Page 2)

Brand names: Primsol

Reviews for Trimethoprim

Commonly mentioned side effects
  • Lad...
  • Taken for less than 1 month
  • May 15, 2022

For Urinary Tract Infection "Was given a 3-day course of trimethoprim 200 mg twice a day. By day three, although UTI pain had gone, I started to feel so ill. Lethargic, achy, itchy, and nauseous, and by day five, I felt so nauseous I struggled to eat much at all. Now, nearly a month later, I still feel rough, have a very uncomfortable stomach and bowel, and feel constantly nauseous, just generally unwell. I think this antibiotic has played havoc with my system, and it is going to take a while for my body to fully recover. I won’t be having it again, I will ask for something different."

4 / 10
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  • Den...
  • Taken for 2 to 5 years
  • February 15, 2020

For Urinary Tract Infection "Have been suffering from UTIs continually for 6 years. Going from Keflex to Alprim. The infection always comes back. Had Alprim before, but this time on day 1, huge headache. Day 2, extremely thirsty, have the shakes, trembling hands, and nausea. I really don't want to finish these but will take 3 all up and go back to the doctor."

4 / 10
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  • Kiw...
  • Taken for less than 1 month
  • July 22, 2021

For Urinary Tract Infection "I had an uncomplicated UTI and was prescribed a 6-day course of TMP. After the first tablet, I developed intense nausea, chills, and overwhelming fatigue. I have now taken 3 tablets and have not eaten in three days. Even the sight of food makes me sick. I pretty much lay on my electric blanket with alternating chills and sweating. I am terminating usage and will never accept this drug again. I think that it did knock out the UTI."

2 / 10
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Frequently asked questions

  • Boa...
  • Taken for less than 1 month
  • September 4, 2020

For Urinary Tract Infection "I have just finished a week's course of trimethoprim for cystitis. It cleared symptoms within a few days, which was great, but they made me feel unwell in myself. I felt nauseous all week and also felt achy and lethargic, as if I were coming down with another illness. Once I finished the course, the nausea stopped, but a day later I woke up to find an itchy rash all over my upper legs-basically an allergic reaction. These antibiotics certainly cleared the infection quickly, but I obviously don't tolerate them very well. However, I was on them for a week, and I think that they can be prescribed for shorter lengths of time."

6 / 10
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  • Vit...
  • Taken for less than 1 month
  • April 4, 2022

For Urinary Tract Infection "I was prescribed this medication, as I had sepsis about 4 weeks ago. They think it's due to an infected gall bladder which the duct is blocked with stones. I can't take any of the -cillin family of antibiotics, so I was prescribed other antibiotics 2 weeks ago. They didn't work, so I was prescribed these. The first day I was fine, the second day I started feeling yuck and not wanting to go out. The second night, I struggled with anxious, horrible feelings which I don't normally have. On the third day, I realized it was these tablets when I looked online and read the reviews. I don't think these should be prescribed at all. I'd rather have sepsis again than feel how I did on this medication. Avoid."

1 / 10
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  • Rin...
  • Taken for less than 1 month
  • March 2, 2021

For Prevention of Bladder infection "3-day course taken after abortion, as I was concerned about infection. I began feeling unwell after starting trimethoprim, with nausea, headaches, stiff neck, sensitivity to light, and possible fever. Worried that these are signs of aseptic meningitis, which trimethoprim is known to induce."

2 / 10
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  • Rub...
  • Taken for less than 1 month
  • September 25, 2021

For Urinary Tract Infection "I was prescribed a 7-day course of this antibiotic, as the 3-day course of Nitrofurantoin did not work, but I think they would have done the job if the course was for 7 days, as I never had any of the symptoms I have with Trimethoprim. All the symptoms I had along with the UTI were awful, exactly as others have described, i.e., couldn’t sleep, felt very sick, was sick, as I just had no appetite for 5 days whilst in them. These tablets should make you feel better, not suicidal. Had a terrible headache and felt weird, and anxiety thoughts went through the roof, ended up in A&E on the second day. I have taken 5 ½ days' worth and now binned the others and will take my chances. I will also let my doctor know."

6 / 10
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  • Ann...
  • Taken for 1 to 6 months
  • October 21, 2021

"I’m a 19-year-old female with extreme and random pelvic pain and frequent urination (up to 15-20 times a day). I was taking 100 mg once a day for a few months to rule out the diagnosis of urethritis. Within a few days, I experienced extremely bad headaches and quite a bit of hair loss. I decided to continue with the medication. A little over a month later, I began experiencing horrible symptoms, which were dizziness, a heavy feeling in my legs, nausea, clumsy hands, shortness of breath after walking or even just lifting a box, a tingly sensation on my feet, and chest pain. I contacted my doctor, and he told me to immediately stop taking it. Even after all of this, there was NO improvement in my urinary frequency and pelvic pain! I will not be taking this medication again."

1 / 10
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  • Kat...
  • May 16, 2022

For Urinary Tract Infection "This review is partly in response to the last review from Stardust: I just wanted to tell you, what you described with your experience I had the EXACT same reaction, so you are not alone at all. I was on 300 mg 1 x day for a UTI, and it completely wiped me out, I was exhausted from day one. I had pounding, throbbing headaches that were unbearable and dizziness, especially getting up or bending over. As I continued taking it, it just got worse. Day 3, I started getting awful abdominal cramps and pains in my lower back, stomach, and legs, diarrhea, vomiting, and terrible nausea. My heart began to palpitate so bad I couldn’t sleep, and my whole body vibrated, and I could feel my heart beating through my body, it seemed. I got hot flushes followed by chills. It is honestly the worst antibiotic I have ever had and would rather put up with the burning when peeing of UTI than suffer these horrible, sickly side effects. Ask for Augmentin or amoxicillin, don’t take trimethoprim! Heed my warning!"

1 / 10
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  • Tom...
  • Taken for less than 1 month
  • March 21, 2023

For Urinary Tract Infection "I started a 7-day course, and by day four, I felt absolutely awful. The side effects of this antibiotic are horrendous. I literally felt worse due to the side effects than having a UTI. The most awful feeling of nausea, one of the worst headaches I’ve ever experienced, overwhelmed by tiredness and fatigue, tummy aches and pains, muscle aches and pains, and just a general feeling of feeling unwell. I can’t wait to get back to some normality again."

1 / 10
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  • Haz...
  • Taken for less than 1 month
  • April 13, 2021

For Bladder Infection "Was prescribed this for a UTI, made me so ill, nausea, terrible constant headache, upset stomach, sweats, chills. I never slept when on them, had weird dreams, and made me anxious. I will never take again and would just rather suffer with the UTI."

1 / 10
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  • Tri...
  • Taken for less than 1 month
  • January 9, 2022

For Urinary Tract Infection "Had a water infection. 7 days of trimethoprim 200 mg prescribed by my G.P. at one tablet twice daily. My infection did go, but I felt so nauseous and spaced out after day 2 of taking them. Day 6, I nearly stopped as I felt anxious for no reason and wanted to eat, but the nausea made it difficult! Horrid side effects for me."

3 / 10
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  • Tri...
  • Taken for less than 1 month
  • January 9, 2022

For Urinary Tract Infection "Had a water infection. 7 days of trimethoprim 200 mg prescribed by my G.P. at one tablet twice daily. My infection did go, but I felt so nauseous and spaced out after day 2 of taking them. Day 6, I nearly stopped as I felt anxious for no reason and wanted to eat, but the nausea made it difficult! Horrid side effects for me."

3 / 10
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  • MBa...
  • Taken for less than 1 month
  • May 16, 2020

For Urinary Tract Infection "Tried Trimethoprim last year, and it made me feel very nauseous. I was hesitant to take it again, however, this time, I have only had mild nausea, maybe a headache, and a sore jaw. I think every experience is different. It cleared up my UTI, so I’m happy."

8 / 10
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  • MBa...
  • Taken for less than 1 month
  • May 16, 2020

For Urinary Tract Infection "Tried Trimethoprim last year, and it made me feel very nauseous. I was hesitant to take it again, however, this time, I have only had mild nausea, maybe a headache, and a sore jaw. I think every experience is different. It cleared up my UTI, so I’m happy."

8 / 10
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  • DRU...
  • Taken for less than 1 month
  • November 10, 2018

For Urinary Tract Infection "Prescribed 20 of these to take over a period of 10 days. Halfway through, symptoms of UTI have gone, BUT I have awful giddiness and nausea with these. After about 6 hours, it wears off, and I feel great till I swallow the next one. Dizziness means it’s affecting work and a headache/stiff neck. Hope I don’t have to take them again, as it makes me feel horrible!"

5 / 10
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  • Anonymous
  • Taken for less than 1 month
  • June 24, 2022

For Urinary Tract Infection "Was prescribed Alprim 300 mg, one each night for 5 nights. Took the first tablet. A headache developed fairly quickly. Headache didn't go away. Went to the bathroom. Felt nauseous and weak. On the way back to bed, my head started spinning, and I passed out. Next day, the doctor changed my prescription to Apo-Cephalexin. Have been taking these for 3 days with no headaches or dizziness. Have never had problems with antibiotics before this."

1 / 10
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  • Mar...
  • Taken for less than 1 month
  • November 13, 2021

For Urinary Tract Infection "Prescribed trimethoprim for UTI one a day for 2 weeks. It has set off my migraines, and I had to stay in bed for 2 days. I can’t eat, feel like I’ve been punched in the stomach, nausea 24/7, rash all over body, plus itching. Worst experience of antibiotic ever !!"

1 / 10
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  • Lee...
  • Taken for less than 1 month
  • April 7, 2023

For Bladder Infection "I have already taken a full course of antibiotics, and the UTI did not clear. The doctor then prescribed 2 x 200 mg daily of trimethoprim. I have taken 4 (2 days), and last night I got a really bad itch across the bridge of my feet, and I could have clawed them off! I've been feeling nauseous and not great at night, restless. I don't think I will be taking these again. However, the UTI symptoms have eased slightly."

7 / 10
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  • Don...
  • September 9, 2021

For Urinary Tract Infection "Given nitrofurantoin at the hospital. Bad reaction. A&E gave me trimethoprim 200 mg twice a day for 3 days. Fine first day and thought I was cured, just felt a bit sick, but today no energy, very, very nauseous, palpitations, and headache. Don't really want to take this for another day. If I could actually speak to my GP, it would be a miracle! Don't want to end back in A&E."

1 / 10
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  • Kay...
  • Taken for 1 to 6 months
  • October 1, 2022

For Urinary Tract Infection "I was placed on it for an embedded UTI, it does get rid of my pain, but the side effects aren't worth it. I was fine the first month, then, the second month, things went downhill suddenly. When I'd have a BM, my heart rate would drop to 40 bpm, and I'd almost pass out. Then, for the next 24 hours, I'd feel miserable, vomit endlessly, and would question going to the ER or psych hospital because my anxiety was so bad and intrusive thoughts-absolutely terrifying. This happened to me four times, and I decided to stop the antibiotic. It's been almost a week since stopping, still have occasional all-over body tremors/shakes, nausea is hanging on, stomach is up and down, but no BP crashes, which is great. I just hope to feel better soon."

1 / 10
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  • Tor...
  • Taken for less than 1 month
  • August 29, 2022

For Urinary Tract Infection "I'm allergic to amoxicillin, so my GP prescribed this medication. I had nausea and a mild reaction for 3 days. I took the 4th tablet tonight. My face has swollen, rash on my hand, tummy tightness, severe nausea, and a terrible headache. I am flying overseas tomorrow, I need rest tonight."

1 / 10
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  • Tor...
  • Taken for less than 1 month
  • August 29, 2022

For Urinary Tract Infection "I'm allergic to amoxicillin, so my GP prescribed this medication. I had nausea and a mild reaction for 3 days. I took the 4th tablet tonight. My face has swollen, rash on my hand, tummy tightness, severe nausea, and a terrible headache. I am flying overseas tomorrow, I need rest tonight."

1 / 10
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  • Sic...
  • Taken for less than 1 month
  • May 5, 2021

For Bladder Infection "Started taking this antibiotic for 5 days, twice a day, and the bladder infection is still here. Antibiotic resistant. Yes, there were side effects, but nothing too bad. Headache, some nausea, but manageable. On a different antibiotic now, penicillin, so fingers crossed it works."

6 / 10
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  • Jan...
  • Taken for less than 1 month
  • July 31, 2022

For Urinary Tract Infection "This was the only drug that I could take that was sensitive to the Klebsiella infection. I tried to take it many years ago and had side effects, so I was reluctant to try it again. I managed 7 days with nausea and tiredness. I finished them 2 days ago, feeling pleased with myself for persevering, and last night started with cramps in my stomach and diarrhea. I'm hoping it stops, or it will be another visit to the doctor."

5 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.