Zepbound and Tiredness: What Users Say

• SMP...
• Taken for 6 months to 1 year
• February 5, 2025

For Weight Loss (Obesity/Overweight) "I’ve lost 43 lbs in the last 9 months. I experienced some mild hair loss (but started this in menopause, so that contributed to hair loss as well), increased heart rate, although mine was low to start, some burping, and tiredness. The worst side effect for me is the diarrhea. I have it starting about 24-48 hrs after injection. It lasts on and off for about 3 days. Overall, these side effects have been mild and manageable. The weight loss has been life-changing!!"

• LML...
• Taken for 1 to 6 months
• January 21, 2025

For Weight Loss (Obesity/Overweight) "5’1”, 180 lbs, 63 yrs. old female, BMI 34%. History of cardiac disease and hypothyroidism. I’ve been taking the 2.5 mg dose for six months with virtually no worrisome side effects. I do experience unusual tiredness within 8–12 hours of each dose. Who doesn’t enjoy a good nap, yeah? I'm currently experiencing moderate hair loss, which is a concern. I consulted my PCP, who agreed we should rule out other potential causes such as a recent change in thyroid medication, nutrient deficiencies, or age before deciding the next step in my weight-loss journey with Zepbound. My current weight is 142 lbs. That’s 38 lbs (an approximate 1.5 lbs/week or 6 lbs/month) weight loss over six months. It’s just the boost I needed. According to the CDC, losing 1–2 lbs per week is a healthy weight loss goal. It’s reassuring to know that my weight loss is at a healthy pace at the lowest effective dose of Tirzepatide. Thank you, Eli Lilly, for the Zepbound coupon card ($25 co-pay)."

• Pag...
• Taken for 1 to 6 months
• July 22, 2025

For Weight Loss (Obesity/Overweight) "I started Zepbound in June 2025. I weighed 190 and 5’5, age 51. As of 7/22/25, I have lost 15 lbs. I feel more confident and happy about my weight loss. I have experienced mild/moderate hair loss. I feel extremely tired in the first 24 hours, sometimes into the next day. I take a regular pre and probiotic helping with regularity. Also taking vitamins and biotin supplements."

• Pag...
• Taken for 1 to 6 months
• July 22, 2025

For Weight Loss (Obesity/Overweight) "I started Zepbound in June 2025. I weighed 190 and 5’5, age 51. As of 7/22/25, I have lost 15 lbs. I feel more confident and happy about my weight loss. I have experienced mild/moderate hair loss, I feel extremely tired in the first 24 hours, sometimes into the next day. I take a regular pre- and probiotic, helping with regularity. Also taking vitamins and biotin supplements. I wish you well on your journey, too!"