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Tioconazole topical and Pain: What Users Say

Brand names: Monistat 1 Vaginal Ointment, Tioconazole 1 Day, Vagistat-1

Pain: mentioned by 287 users (16.9%)

Based on user experiences from 1,696 Tioconazole topical reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

burning 67.7%
itching 53.2%
swelling 19.3%
pain 16.9%
discomfort 7.8%
irritation 4.2%
discharge 2.5%
tingling 2.2%
soreness 1.8%
stinging 1.6%

Reviews for Tioconazole topical

Commonly mentioned side effects
  • My...
  • Taken for less than 1 month
  • January 2, 2016

For Vaginal Yeast Infection "Pretty sure this egg ovule isn't filled with medicine, but a tiny FIRE-BREATHING DRAGON that has hatched and is now spewing its red-hot flames all over the walls of my pink canoe. I feel as if I am straddling an active volcano as it erupts inside of my hoo-ha. My lady bits are the new Pompeii. I'm pretty sure this medicine has turned my bits into a furnace. The only relief from what feels like birthing Satan himself has been waddling over to my freezer and wedging as many ice cubes as possible between my sizzling meat flaps. The pain of this wretched excuse for medicine can only be compared to mistaking a tampon for a stick of dynamite. Best of luck to my fellow yeasties! RIP to our vaginas."

4 / 10
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146 Report
  • Emi...
  • Taken for less than 1 month
  • December 17, 2020

For Vaginal Yeast Infection "Skip this product. I’ve had 2 vaginal yeast infections before from taking antibiotics, and AZO Yeast Plus has always worked for me. Well, my pharmacy was out, and they didn’t have Monistat, so I grabbed Tioconazole 1 Day. I did my nightly routine, and right before bed, I inserted the medication (around 10:30 pm). Instantly, I felt burning that wasn’t there before. I brushed it off and went to bed. I woke up at 3:03 am with the worst pain in and out of my vagina. It felt like a shard of glass was stuck in my vagina, preventing me from sitting up correctly. I went to the bathroom after forcing myself up, and I felt okay to lay back down. I woke up this morning at 7 am, and my vagina is literally swollen. This was my first time ever using this product, but I will never buy it again."

1 / 10
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61 Report
  • Cur...
  • December 19, 2019

For Vaginal Yeast Infection "DO NOT USE! Although if you are reading this, I suspect you already have and are now currently experiencing the raging fire from hell in your vagina, accompanied by the painful swelling replicated only by pushing a tiny human out of your vagina. I bought the Monistat brand at full price, so I wasn’t going for the cheap stuff. I didn’t look up reviews first because who would think such a volatile product would exist? I inserted the medication at 11 pm, within minutes I felt the burning, but I left it in and took some sleeping medication, hoping to wake with a bit less discomfort than I’d had the last few days. I WAS SO WRONG! Seriously, I had a child WRECK my vagina during birth, and this pain and swelling are comparable to that. All I can say is that the medication dang well better work because I’m currently sitting in a bath of baking soda and had to cancel all plans for today. RUN. If you were smart enough to look up reviews first."

1 / 10
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65 Report

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Frequently asked questions

  • Dra...
  • Taken for less than 1 month
  • August 3, 2019

For Vaginal Yeast Infection "If you’re like me and used this product before reading the reviews, just know, you may also like to ready an ice pack and an anti-inflammatory of some kind! I’m about 6 hours in and I’m pretty sure there is a tiny flamethrower inside the applicator. I read the instructions and it clearly states that remaining product can be applied to the outer parts, but unless you’re into pain, don’t do that. My lady bits started throbbing from the pain and now they have been renamed my no-no place!! It’s swollen and itchy and 12x worse than when I began this horrid road to recovery. I have faith in my who-ha that she will bounce back, but of all the beatings she’s taken over the years, this one’s got to be the worst few hours in her history."

2 / 10
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54 Report
  • S L...
  • Taken for less than 1 month
  • July 15, 2021

For Vaginal Yeast Infection "If you’re reading this, chances are you're already having an adverse reaction to this medication. I inserted it at 9 pm and woke up at 2 am with intense pain, swelling, and itching. I didn’t see any comments with advice on managing this, so I thought I would post what I did. I took a dose of Benadryl, ibuprofen, and put a pillow between my legs to keep them apart. By 9 am, the pain was gone, and I believe my yeast infection symptoms went with it. So in the end, I guess it worked, but it was so not worth it."

1 / 10
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26 Report

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  • Jul...
  • Taken for less than 1 month
  • February 27, 2020

For Vaginal Yeast Infection "I do NOT recommend. I wish I would have read reviews beforehand. I’m highly upset I wasted time on this product. I didn’t experience any burning or extreme itching when I put it in, but I did wake up to a severely swollen vagina, and now it hurts to do anything. I’m so uncomfortable and can hardly sit down. I regret trying this and not just sticking with the Monistat 1."

2 / 10
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22 Report
  • Tha...
  • December 17, 2014

For Vaginal Yeast Infection "I had gone to the doctor already and was given a one-time use pill for a yeast infection, plus antibiotics for a urinary tract infection. The itching and burning continued despite these medicines. I bought this product and decided to try it even after reading the negative reviews. I was desperate and already in the midst of extreme itching and pain, so I used it at 1 a.m. when I woke up again due to the irritation. Once I inserted it, I felt immediate relief, and I do mean immediate. I don't understand the negative reviews, maybe each person's body reacts differently, but I would highly recommend this product."

10 / 10
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38 Report
  • del...
  • Taken for less than 1 month
  • July 19, 2018

For Vaginal Yeast Infection "Well, as you will read, this product was the WORST. Five minutes after inserting the egg, it began to slowly tingle, which turned into an itch that turned into an intense burn. I sat in the toilet for a solid hour before the burn went away, and I think it's because the pain was so bad I was numb down there. LOL But I rated it a 5 because after that hour the pain was about a 1/10, and I didn’t feel itchy at all, and a day later I believe my YI was completely cleared up. I only recommend you use this item if you can push through some pain. Try taking something that will put you to sleep 30 minutes before inserting the egg. Also, not going to lie, reading these reviews helped a lot to ease the pain. God be with us all. LOL"

5 / 10
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22 Report
  • Kia...
  • Taken for less than 1 month
  • February 15, 2020

For Vaginal Yeast Infection "Well, as the others, I tried the 1-day Tioconazole, and my goodness! Why did I do that? My vagina is swollen, itchy, and pain, pain, and more pain! I was not prepared for this. Right now, I am currently laying in bed with my legs up in the air."

1 / 10
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18 Report
  • Ful...
  • Taken for less than 1 month
  • June 28, 2016

For Vaginal Yeast Infection "So I realized how people never come back to say if the product actually worked or not. Well, I'm here to tell you it does. I used this product about a week ago and came here to write a horrible review on how irritated, sore, raw, burning, and itchy I was from it. I started feeling these side effects about 1 hour after I put the hellish egg in me. After about 2 days, the symptoms went away and fully healed my YI. I am completely back to normal. Bottom line is the product DOES work and can heal your symptoms fully within 48 hours...only if you're up for the painful side effects. Honestly, if I had the option to use this again, I probably would because it works CRAZY fast."

4 / 10
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21 Report
  • Ang...
  • July 31, 2017

For Vaginal Yeast Infection "Listen up. I shoved some of that Monistat 1 in my downstairs hallway last night, and holy Lord Vulvamort, was that a bad idea. You'd think, well, 1 day of treatment is way better than 3 and definitely better than 7, but trust me, if you don't want your baby cave to feel as though it's been torched by Satan himself, stick to the multi-day. Then, while writhing in pain and trying to stop the devil cream from burning a new hole down there, I read the reviews. This is a common thing that happens with the Monistat 1. Don't use it."

1 / 10
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17 Report
  • Fir...
  • Taken for less than 1 month
  • November 10, 2019

"I’m only about 5 hours into this Monistat 1 experience, and at this point, I don’t even care if it works. Nothing is worth this burn. My poor coochie feels like what I can only imagine as the depths of hell. Hot lava-level pain. I read the entire pamphlet, and this was not a warning, and after seeing all these reviews of other women experiencing the same, it DEFINITELY should be! If you are considering buying this product, do not do it! It’s not worth the risk. I’m sitting here at 5 a.m. typing this review because the pain is keeping me awake. I have survived second-degree burns on my entire hand before, and this is nearly comparable to that, but there is literally nothing I can do about this one except wait it out. The anti-itch cream that came with it is worthless and does nothing for me. If you are reading this because you just used the product and are starting to realize something is off, Godspeed to you, sister. I wish you luck."

1 / 10
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13 Report
  • Sam...
  • Taken for less than 1 month
  • July 2, 2015

For Vaginal Yeast Infection "I was terrified to try this product because of the reviews I had read, but I just had a feeling I would be fine. I put in the pill a few hours before bed Tuesday night and was completely fine and got to sleep without ANY pain, and when I woke up I was still feeling sore and I had lots of discharge, but by the end of the next day I was symptom-free. It's now the following day and I'm feeling back to normal, however, there is still a white discharge, but I read that that is normal because the medicine has to leave your system. Overall, had NONE of the issues that I had read about in reviews. Extremely pleased."

10 / 10
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18 Report
  • Va ...
  • June 27, 2017

For Vaginal Yeast Infection "I have used Monistat 1 about a year ago and a few more times before, it worked great, relief within 24 hours. My current experience is a complete 180. The burning and itching are unbearable. I can't imagine what the makers have done differently, they need to go back to the original formula, which worked fine. I wish I had used the 3-day or just gone to the doctor. It's bedtime, but the pain is keeping me awake. I will never purchase again!!!!"

1 / 10
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14 Report
  • Why...
  • Taken for less than 1 month
  • January 2, 2020

For Vaginal Yeast Infection "So, like everyone else, I didn’t read the reviews. I inserted the medication and realized I had more itching than before, I also noticed the burning a lot more. To make matters worse, I used the cream for the external area, and I think I made it worse!!! I was trying to save a few dollars, never again. The pain isn’t the worst, but the itching is absolutely horrible."

3 / 10
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11 Report
  • Vag...
  • Taken for less than 1 month
  • January 21, 2017

For Vaginal Yeast Infection "They should really put a warning on the label of this medication. Used it at bedtime, woke up at 1 a.m. with a burning itching that was not relieved by any method. Completely miserable. I do not know why so many women react this way, but there should be a significant warning placed on the label. I'm going to reach out to the FDA. Beware of this medication. Hopefully, you read this before use, not after. There's nothing that's been able to relieve the inflammation, pain, and itching. I'd rather have a yeast infection for the rest of my life than have to feel this way."

1 / 10
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15 Report
  • Lau...
  • Taken for less than 1 month
  • March 15, 2019

For Vaginal Yeast Infection "So I used this same product in 2016. Now, fast-forwarding to 2019, I find the need to put my Vag through this hell. The Monistat causes itching, burning, and pain like no other, because it is constantly there with no ceasing. You will not sleep, concentrate, or be in a good mood while this extremely strong medication is doing what you paid to do - kill the yeast infection! I am literally writing this review as I am sitting under the massive discomfort of this medication. I don’t discourage anyone from using it, however, I put out a disclaimer: BEWARE! It will test your character, patience, tolerance, and soul! But it works, it will get rid of an itch, odor, and burning from YI. Time: It takes about 1-2 hours for the gelatin egg to dissolve, and the burning, itching, and discomfort to start. Length: This varies. Discomfort could last from 1 hour to eternity."

8 / 10
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10 Report
  • Don...
  • Taken for less than 1 month
  • November 7, 2020

For Vaginal Yeast Infection "I purchased this Tioconazole 1 Day product on a Tuesday, and just like the others, my vagina swelled shut. I was in terrible pain. I’m on Jardiance, so YI are common, and normally I’d take Diflucan or I would use Monistat 7, and in a day or so I’m good. However, using this product is a different story. Here it is Friday, and I’m still itching and in pain. This product is not worth the $10 I paid. I highly recommend that this product be avoided at all costs. It was not effective and caused me pain."

1 / 10
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9 Report
  • Sta...
  • July 2, 2016

For Vaginal Yeast Infection "It has been 3 years since I tried this product. Somehow I had forgotten how horrible it is! I used the Monistat 1 Day ovule at 4 pm for a standard yeast infection, wanted to stop it before it was full-blown. By midnight, my vag was on fire, and by 2 am, my labia was so swollen it was hard to walk without pain! I used this 38 hours ago, and I'm still in pain! This product is poison! Do not use if you value your health and sanity! Nightmare! Shame on the partner companies (Prestige Brands Holdings, Inc., the makers of MONISTAT®, and Vertical Pharmaceuticals, LLC) that make so much money off a known severe symptom-causing product. All female executives that have a hand in marketing and promoting this product need a sample dose of the fire ovule!"

1 / 10
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16 Report
  • Ouc...
  • May 25, 2017

For Vaginal Yeast Infection "I have had yeast infections quite a few times! I have always used Monistat 1. The first time I used it, I freaked out my whole family, I was screaming and crying, telling them to 'Make it stop!' And I've used it a couple of times since then, and it has been completely fine with no burning. I'm using it tonight and feel like I'm dying again! It always works and clears it up, but be prepared for the worst pain for a few hours!"

7 / 10
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11 Report
  • Ray...
  • August 23, 2015

For Vaginal Yeast Infection "Omg.... the pain!!!!! I was put on antibiotics for pneumonia and bronchitis and ended up with a YI... so I got the one-day treatment, got $24. At 8:30 pm, I popped it in, by 9:53 pm, I was in so much pain, it burned so bad and still is burning. It's now 11:33 pm, it burns so bad I'm in tears, bawling... and I am contemplating removing my shower head from the hose to flush it out. I am in tears and afraid to move. With the slightest shift, I feel like I am relighting the torch inside me. Do not do this treatment.... and these people who say they hardly feel a thing.... yeah, they have vaginas cloned from Superman DNA... I would rather do natural, no pain meds, childbirth again before doing this treatment again!"

2 / 10
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12 Report
  • Ano...
  • October 6, 2016

For Vaginal Yeast Infection "My mom told me to try this to help my infection. I had no problem putting it in, it was just like a tampon. Everything was fine for the first hour, maybe 2 hours, but suddenly it has become so uncomfortably painful and itchy. I don't know how to make it stop!! :( I hope it ends up being worth this. (Honestly, the yeast infection wasn't this bad)"

1 / 10
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11 Report
  • hel...
  • May 7, 2019

For Vaginal Yeast Infection "To whom it may concern, DO NOT USE MONISTAT. This product says side effects may include 'mild increase in burning or stinging.' That is an absolute lie, this product made my symptoms SEVERELY WORSE. It made me feel pain go from a 1 to a 10 in a matter of minutes. This product made me feel absolutely awful, and whoever came up with the product should use it themselves to see how painful it is. This product made my symptoms so much worse, and the burning and itching of the cream will not go away. Why is this product still allowed to be sold if a very limited amount of people are being given relief? Poor people buy this product to seek help and to find relief, but it just makes things 100 times worse. Absolutely horrible, and someone needs to do something about getting this product off of the market. I am still trying to seek relief for the burning this product has given me."

1 / 10
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10 Report
  • Lit...
  • December 11, 2018

For Vaginal Yeast Infection "Yeast infection wasn’t going away with the oral capsules that the doctors prescribed... So I tried this. My feet are literally withering in pain. It’s 1 am and my vagina is crawling around the pits of Hell having a grand old time. Girls, don’t do this to yourself. Read the reviews, goddamnit. Having an ice pack between your legs is not exactly thriving. Please love your lady parts more. Goodnight. Rip Vag."

1 / 10
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8 Report
  • Itc...
  • July 17, 2016

For Vaginal Yeast Infection "So I just put the egg in about an hour ago. I've used this a few times before, and it worked like a charm. This time, within a few minutes of inserting the egg, the worst and most uncomfortable pain I've ever experienced. I literally cried for almost an hour. I didn't want to remove the egg in hopes that I could tolerate the pain and itch and that I would be all better soon. I read that plain yogurt (cold) relieves the itching and burning and helps rid of the YI bacteria. Desperately and thankfully, I had some plain yogurt in the fridge. I applied it all over my vagina as well as inside my vagina while the egg still remained. It took away the itch, burn, and pain almost completely. Sounds weird, but try it! Hopefully, I can help someone else out."

5 / 10
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10 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.