Zelnorm for Irritable Bowel Syndrome with Constipation User Reviews

• Jus...
• Taken for less than 1 month
• March 15, 2020

"I used Zelnorm before it was taken off the market and love it. I’m taking it again now it’s back, and it isn’t working for me. Anyone else having the same problem? Is there something missing now that was there before? Why doesn't Zelnorm work like it used to?"

• jod...
• Taken for 1 to 6 months
• February 5, 2020

"This medicine, Zelnorm, works wonders. I’m a 22-year-old female that has IBS with constipation for about five years. I’ve tried every single constipation medicine out there. All made me feel horrible. They finally brought this back on the market, and I am regular every day now. Saved my life."

• Anonymous
• Taken for 1 to 2 years
• February 15, 2019

"This was the best only medication that ever worked for IBS-C for me. I was diagnosed in the late 90s, and this medication was a miracle in the mid-2000s. It’s the only time I had no pain, no bloating, no problems, didn’t have to worry about IBS symptoms. Now, it’s the only thing I can ever think about because it’s a constant problem. I never felt better than when Zelnorm “fixed” my gut. Seriously, they need to BRING BACK ZELNORM. For the sake of everyone here!"

• DG3...
• May 30, 2013

"This is the ONLY medicine that worked for me! I have tried everything else, and nothing works! I will bet if it was for erectile dysfunction, it would still be on the market! You don't see Viagra black-boxed, which causes cardiovascular problems, and more than likely this is because Zelnorm helped a more predominant female health problem!"

• Bri...
• Taken for 2 to 5 years
• May 6, 2019

"Zelnorm was amazing for my IBS-C. Took away the bloating and worked well for my constipation. Helped me lose weight. Currently on Linzess, and I’m feeling horrible. Weight gain! Back pain, tired, feeling weak from bowel movements coming out like water. Stomach is extremely bloated, making gurgling noises. Living in the bathroom instead of getting to spend time with my family. Soon as I do eat, right to the bathroom it is. Praying they bring back Zelnorm so I can enjoy my life again, as well as feeling better."

• Luc...
• October 3, 2009

"I have suffered from IBS for several years now, and it is ruining my life. I have tried countless medicines to treat the symptoms, tried diet modifications, everything imaginable. I'm only 22 years old and it breaks my heart to know that my quality of life is so affected by this, and that there is a cure for me, Zelnorm...but I can't have it! The 1/2 year that I was on Zelnorm was the best year of my life. I had energy, felt good enough to get out of the house and participate in life. There is nothing that works like Zelnorm and I wish someone could bring it back, or at least give all of us sufferers some answers. Walk a mile in our shoes."

• Bla...
• September 21, 2020

"Without a doubt, this Zelnorm is the best med ever for IBS w/ constipation. It is a reliable, comfortable drug for this problem. I went to the pharmacy today for this prescription, it was insanely expensive. I have to reconsider because of the price - what a shame."

• Bet...
• Taken for less than 1 month
• November 5, 2020

"I also took Zelnorm before they took this off the market in 2012, and it was the best thing ever. I have been back on it almost three weeks now. It worked great the first week maybe, and now it’s not doing anything. It’s a new manufacturer. I wonder if it is not the same exact ingredients. I will continue to take it for a while longer and hope it starts to work again."

• Del...
• May 4, 2021

"This was a miracle drug for me when I took it years ago. I have had IBS-C my whole life, and when this was pulled from the market, I cried. Not only did it help with constipation, but it made my entire stomach feel great. No bloating, nausea, excessive diarrhea, or sluggish feeling the rest of the day. When it was pulled, I was started on Amitiza, which didn't work at all. Now on Linzess and take it at 7 a.m. I can't leave the house until 1:00 p.m. because of excessive diarrhea. My stomach bloats, I feel sluggish and fatigued. I was ecstatic when learning Zelnorm was back on the market and immediately called my gastroenterologist. He sent in a script for it, and I found out insurance won't cover it, and it's $400+ for a 30-day supply. The pharmacist suggested I apply for the patient assistance program, and I tried but kept getting 'error' when following the link on the pharmaceutical website. Frustrated!"

• Anonymous
• May 28, 2008

"I took Zelnorm for Irritable Bowel Syndrome for about 2-1/2 years. From the first dose, my abdominal distention, bloating, and pain disappeared by morning. It was a miracle drug. When I didn't take it, my quality of life was non-existent. I tried many medicines over the years, none helped. Just had to 'wait out' the severe pain and bloating. I feel Zelnorm should be available for those individuals not at risk for cardiovascular problems. Unfortunately, there isn't anything else that works in the same way."

• Anonymous
• December 11, 2008

"I too suffer from severe constipation and have for years. I am in my thirties, and this is the only drug that has helped. I felt so much better when I took Zelnorm. I had more energy, it cleaned me out, mood swings were less, and the bloating, pressure, and gas were next to nothing. My quality of life was amazing while taking the medicine. However, I did have to plan when I took Zelnorm. I had to make sure I had a day off from everything before I could take it because within 1-2 hours of taking the pill, I would make many trips to the bathroom for 1-3 hours. Then I would get extremely tired. After a short nap, I felt like myself again. I would only have to take 1 Zelnorm two to three times a month. It seemed to have regulated me for the most part. Then the letter came in the mail discussing the withdrawal of the medicine. I then stopped taking Zelnorm for a while. Until my constipation symptoms became worse, I took Zelnorm out of desperation for relief. I now only take it in emergencies when I cannot find relief."

• Anonymous
• September 3, 2008

"I've suffered from severe abdominal pain and constipation since I hit puberty. I was in such pain that I would pass out from it. After a week of taking Zelnorm, I felt completely better, and I didn't pass out once from pain while I was on it. It was what got me through 2 years of high school, when before, I was constantly hospitalized from it and couldn't attend school. I was taken off of it because my doctor was worried about the side effects, and the pain and other problems came back, just not as aggressively. I learned to deal with it, to ignore it, and the pain slowly went away. I recently had an attack for the first time in 4 years that was extremely severe, and I passed out. I don't want to spend another year in and out of the hospital..."

• Anonymous
• July 14, 2008

"I am in the same boat. After years of suffering, I reluctantly started Zelnorm. I was on it for just a few months before it was taken off the market. Since then, it has been a constant struggle, and no other medicine or alternative source seems to help. I would like to take it despite the risks and really wish there was another option that worked as well."

• Tou...
• May 14, 2008

"I am 53 years old. I have had serious problems with constipation due to irritable bowel syndrome for years. I was only able to take Zelnorm for two months before it was removed from the market, but they were the best two months of my later adult years. No pain, easy bowel movements, loss of doughy feeling in my abdomen, less tired, and more symptoms were gone with Zelnorm. If you can't bring it back, please find an alternative that works as well. PLEASE!"

• Amy...
• May 12, 2019

"I suffer from IBS, which is a chronic condition for constipation, bloated discomfort. When my doctor introduced me to Zelnorm, that was the best medication because I tried so many medications and it did not help. I was losing weight, energetic, happy. Please put Zelnorm back on the market, this saved a lot of lives. I didn't have any side effects from the medication, I was healthy."

• Chi...
• February 10, 2021

"I took Zelnorm the first time around, and it was a great drug. Then it was taken off the market. Now I am taking it again, and I do not think it is the same Zelnorm. It worked the first week or so, then quit."

• Anonymous
• July 30, 2009

"My stomach was not bloated, and my intestinal tract was functioning as it never has before-I felt more alert, less tired and sluggish, and even lost some weight. I am very upset that this was taken off the market."

• Anonymous
• May 14, 2010

"I miss this drug more than words can describe. I was on it for about 3 years, and for those years, I was completely 'normal.' When I was told that this drug was going to be taken off the market, I was very confused. I was also very confused about the claims that were made, and are still made about this drug. I'm a man, and this drug was the best thing to happen for my condition. I also wasn't the only man on this drug either. Almost everyone who has severe IBS, male or female, that took this drug felt extreme relief with little to no side effects. Now this drug isn't even being considered to come back, let alone for males. What really happened to this drug?"

• PAM...
• February 8, 2020

"OMG, I am so thankful that Zelnorm is back for people that have gone through terrible constipation, as I have. At first, I did not think it was going to work, then, the next day, I took Miralax and a Zelnorm, and they work well together."

• Ste...
• Taken for 1 to 2 years
• December 22, 2018

"I have not been the same since this pill has been taken off the market. I swear they took it off as it works so well. Maybe if they would have charged more and they would have made more money, they would have kept it on the market. Sad, really. I’m demanding to bring it back. Was the best drug ever."

• Pil...
• Taken for less than 1 month
• January 22, 2017

"For me, there are no side effects. I took this medicine twice in a month. Saturday at 6:00 a.m., 6:30 full glass of water. 8:00 a.m. @ bathroom stops, 9:30 a.m. The third time I tried to use it, it does not work. I like the medicine. In Puerto Rico, it is not for sale anymore."

• deb...
• Taken for less than 1 month
• September 19, 2020

"I've tried this medicine 2x. The first pill gave me severe diarrhea an hour after just one dose. 3 episodes within a few hours. Second time, a week later, same result. Never again. I tried what my doctor wanted me to do. But I can't tolerate it."

• Mic...
• Taken for 1 to 6 months
• December 4, 2018

"Have both IBS and IC. Zelnorm stopped symptoms of both diseases. No adverse effects-none. On my brief drug-induced IC remissions, the IBS was not present. A GE conference in Munich in December 2008 had a presentation that in a follow-up study on patients in control and test groups of the original study had a dozen cardiovascular deaths in the control and none in the test side. That's exactly opposite of what the original study asserted. It was also pointed out mistakes in assembling the original data-false positives and soft angina. My source was Cardiology Today. The doctors presenting speculated why Zelnorm prevented cardio problems. I saw study after study praising the results of the drug. 11 years of misery: imagine how I feel. It should not have been pulled. Leave it at that!"

• Wil...
• January 27, 2024

"Zelnorm has been a life saver for me! I was on it years back then it got jerked off the market. I agree with the person that mentioned Viagra wasn't taken off the market. Has anyone read its side effects? I finally got put back on Zelnorm, then my insurance sent a letter saying they won't cover it anymore. This is one of the best medications for IBS-C. For me, it's not right that your insurance can make that call when you know your body, and your gastrointestinal doctor agrees!"

• Cai...
• Taken for less than 1 month
• September 21, 2021

"I don’t have IBS, probably one of the reasons it didn’t work. I have Gastroparesis, low colon motility. I have a lot of paralysis throughout my GI tract, and we tried this medication hoping it would help, but I got such severe acid reflux I couldn’t keep any food down. It was constant heartburn and coughing. Probably not a symptom everyone has, but it was unbearable for me. I also gained so much weight, and I was so bloated."