Sofosbuvir / velpatasvir User Reviews & Ratings

• Gra...
• Taken for 1 to 6 months
• June 14, 2021

Sofosbuvir / velpatasvir for Hepatitis C "Wanted to take this time and let everyone know about my experience. I started taking my Epclusa on March 22, 2021. Just finished my last dose tonight, June 13. I did not miss a day of work and worked out five days a week during the entire treatment. I have been virus-free since my first test at week four and have remained virus-free throughout. Will have my SVR test sometime in September. For those of you who are concerned about starting treatment, I found it to be a breeze and I am sure you will too! Thankful for this treatment as I am at stage 2/3 fibrosis and hopefully I will regress to a lower stage if not completely. Good luck to everyone getting ready to start."

• Hay...
• Taken for 1 to 6 months
• July 4, 2021

Sofosbuvir / velpatasvir for Hepatitis C "I have finished my first bottle of Epclusa, and am now on week 5 of treatment. So far I’ve had no side effects that I have noticed, because I already had headaches and diarrhea before treatment. I had to stop taking my heartburn medication because of the drug interaction. I will get my first round of blood work this coming week and am very hopeful this medication has worked for me. It has honestly made me feel better about myself as a person. I am 3 years sober of IV Meth use and this was the one thing from my past I was still dragging around… hepatitis. I feel once this is over with I will have completely gained my life back."

• Rod...
• Taken for 1 to 6 months
• October 30, 2019

Sofosbuvir / velpatasvir for Hepatitis C "I just want people to know that when the Epclusa is killing the Hep C virus in your body, you're probably going to feel a little nausea. The virus is multiplying millions of times in your body - there's a war between the Epclusa and the Hep C. Just hang in there, you'll be glad when the 12 weeks are over. God bless."

• Sto...
• Taken for 1 to 6 months
• January 19, 2021

Sofosbuvir / velpatasvir for Hepatitis C "I have 5 days left of Epclusa. The first two months I experienced some headaches and tiredness. This 3rd month is really taking a toll on me though. The headaches are worse, and I have no energy. I’ve felt too weak to even go to work for the past week. The worst part is I feel like I’m losing my mind. I don’t know if it’s depression or anxiety or what, but it’s definitely very difficult to function in a normal, healthy way."

• tas...
• Taken for 1 to 6 months
• July 11, 2025

For Hepatitis C "So I've been on the generic of Epclusa for 6 weeks, and I, to be honest, hate it. I'm counting down the days until I'm off of this stuff. The depression is brutal, that is a side effect, and if you already have minor depression before it, it can exacerbate it. I never really had a problem recently with depression, but after like 3 or 4 days of taking this medication, I've just been weepy, and that aching in your chest, and just really depressed. Also, brain fog and not sleeping at all or not very well, and I already had problems sleeping. I did, I think the only thing I've noticed about this medication is I have a little bit more energy, and I haven't done my blood work yet. I'm supposed to do it after 2 months on this medication, but I did get some blood work done for my primary doctor, and my AST and ALT went down from 300 plus to 24 and 25, so it is working but at a cost. I do have a very high viral load, 22 million, and I do have moderate to high fibrosis of the liver. Just being truthful."

• Bla...
• Taken for 1 to 6 months
• September 6, 2019

Sofosbuvir / velpatasvir for Hepatitis C "Well, on my first review on July 28, 2019, I said I'd come back after a bit. Now I am just over halfway through my treatment. I get what you all say about tinnitus. Also, when I wake up in the morning, I'm the same with feeling rough. But once I've had a coffee, it dies down. My feet have been aching a bit, as has my back, but I've had no sickness or headaches. I think that if you have a life-threatening disease like hep C, which is never going away, then it's like carrying bad luggage around every day. If you get a chance to get rid of it and there are a few side effects that are quite manageable, then it's got to be worth it. I felt okay apart from brain fog at first, but it's got a bit worse as I've gone on with meds. But I am more than willing to suffer these for 12 weeks than stay sick forever. I hope you all have the best time on Epclusa that you all can and become hep C free. Take care, people."

• AWa...
• Taken for 1 to 6 months
• April 11, 2021

Sofosbuvir / velpatasvir for Hepatitis C "Think about it, people! How many of you received this medicine free, or better yet, my company insurance paid 80 percent of $72,000. Guess where the other came from? A coupon that Epclusa provided. Ever heard of that before? It's been 15 months since I finished my last pill. My stomach looks as if I have cirrhosis, it feels like I have an infection in my stomach, I'm like the other lady states about hormonal issues. I'm 65 and started having acne. I'm extremely depressed. I've developed major arthritic symptoms. This drug has cured the hep C but my day-to-day journey is horrific. I do not recommend this drug. Your doctor will tell you there are no side effects. How do they really know? I'll never listen to any doctor again. When any medication has only been around for a short period, don't label it as no side effects. Hope your doctors and drug manufacturers can sleep good at night because you won't!"

• Gra...
• Taken for 1 to 6 months
• November 9, 2020

Sofosbuvir / velpatasvir for Hepatitis C "I was an intravenous drug user from age 19 to 32 years old. Clean from all drugs from February 1, 1988, to present. I have had hepatitis from age 19 to 65 years old and 6 weeks on Epclusa with nondetectable test. I had hep C genotype 1A. So grateful for Epclusa. It has allowed me to live longer than expected and 6 more weeks until treatment is completed. Very mild side effects (headache, mood swings, and light depression) so far. At the age of 45 to 50, I did interferon/ribavirin 3 separate times and never was able to finish due to terrible side effects. Epclusa will and is going to save my life. Thanks to everyone that made this happen."

• She...
• February 12, 2021

Sofosbuvir / velpatasvir for Hepatitis C "Started Epclusa in March 2019 for Hep C type 2b. I ate small items/meals throughout the day. Stayed hydrated and avoided any caffeine. Took the pill at 6 am with a piece of bread. I was on an extreme health regime while taking it. Didn't experience anything terrible. However, after the treatment was over, any form of caffeine gives me a 3-day migraine. I am more sensitive to all chemicals in food and drink and get headaches easily, including from fructose and sugar in small amounts. Before Epclusa, I only got headaches when trying to cut back on coffee due to caffeine withdrawal. I noticed that my adrenals and emotions seem to escalate quickly. While I am happy that Epclusa cured my hep C, it also significantly changed my life. It is now January 2021, and I still experience these symptoms. I am very hesitant to get the Covid-19 vaccination due to the headache side effect as I fear my head may explode. Hope this information helps someone."

• Rod...
• Taken for 1 to 6 months
• December 20, 2019

Sofosbuvir / velpatasvir for Hepatitis C "I live in southeast Missouri. I'm beginning my 3rd month on Epclusa. Just went in to get my blood results, my Hep C virus is gone. Still got one more month of treatment. I've had zero side effects. This medicine is a lifesaver."

• The...
• November 10, 2019

Sofosbuvir / velpatasvir for Hepatitis C "I am Genotype 1a, 59 years old, male, active, and otherwise healthy. I was diagnosed in 1995 but have not really suffered any ill effects of the virus other than mild liver enzyme imbalance. All of my FibroScans over the years have shown only minimal scarring. My doctor says Epclusa is a 'perfect fit' for my situation. I’m just starting my fifth week of treatment, with no missed doses. As for side effects, I’m putting 'extreme fatigue' at the very top of my list. Nausea, headache, and diarrhea come and go a bit, but the fatigue and achy joints are up there. But it is absolutely the right choice, no matter the annoyance of these temporary yet fruitful ill effects. I say hang in there and enjoy the added years to your life. Love to all."

• And...
• Taken for 1 to 6 months
• August 16, 2020

Sofosbuvir / velpatasvir for Hepatitis C "I was diagnosed with Hep C. I was prescribed Epclusa. From the very first tablet, I felt something working inside. Within one month, my count was down from millions to low numbers. The course was completed, and I am now Hep C free. No side effects whatsoever. Thank you Gilead and the NHS!"

• rob...
• Taken for 1 to 6 months
• June 30, 2025

Sofosbuvir / velpatasvir for Hepatitis C "I took Epclusa as soon as it looked like a winner, about 6-7 years ago. I had no side effects or nausea at all. After 2 months, tests said I was good. Retested a few times over the next couple of years, and I am clear of the whole thing ever since. My liver damage was minimal with no other organ damage, so I was lucky, even after almost 50 years with the virus in me. I have been eating a high-value organic diet and taking many herbal things to help me stay on top of what I knew was a low-grade inflammation all those years. It worked until science figured out how NOT to kill the patient, and then my naturopath and I decided it was time. I highly recommend Epclusa."

• Anonymous
• Taken for 1 to 6 months
• June 18, 2019

Sofosbuvir / velpatasvir for Hepatitis C "The first 3 weeks of using Epclusa was insane... I was incredibly tired & nauseous. Like a mix of morning sickness and the worst hangover of your life. I used the comfort meds for the entire 90-day ordeal. However, now 3 months after my treatment I am still hep-free, and am living a normal healthy life. I have no lingering side effects. Mentally, it was refreshing... like the last trace of damage I had done while being in active addiction had been erased. Like I now have a clean slate. It has been an incredible gift, despite the 90 days of wanting to throw up. I would 100% do it again. It was worth it."

• Ash...
• Taken for 1 to 6 months
• February 11, 2020

Sofosbuvir / velpatasvir for Hepatitis C "I gave blood and found out I was Hep C positive! Been on Epclusa for 2 months and didn’t have any side effects until month 2 when I started itching all over and noticed some random big bruises on my legs! Called the doctor and they ran tests and found out my test for Hep C is negative, all thanks to this medicine! Only one more month! Stay strong, y’all!"

• Kel...
• Taken for 1 to 6 months
• November 23, 2016

Sofosbuvir / velpatasvir for Hepatitis C "I am on week 8 of a 12-week regimen of Epclusa. The first couple of days, I did have a slight headache, but since then, I haven't had any side effects. I had blood work done at week 5. I was already undetectable! Thanks to an Epclusa coupon, my copay is $5! Other side effects include: the whites of my eyes are white again! I have energy like I haven't had in 20 years. My skin is younger-looking. I sleep like a baby. The slight depression that I used to feel from being so tired all the time is gone. I can get out of bed so easily now and feel energized throughout the entire day. It is hard to go to sleep sometimes because I still have so much energy. I am so thankful for this medication. This has given me quality of life again. Thank you, Gilead!"

• Jef...
• Taken for 1 to 6 months
• April 23, 2021

Sofosbuvir / velpatasvir for Hepatitis C "I just finished my 12th and final week of taking Epclusa one week ago. I probably got Hep C in the Army during the early 1970s. I am now 68 years old. These are the side effects that I noticed: Brain Fog. Just not able to think clearly and rationally. Insomnia. I had to get medication to sleep. My normal libido was gone soon after starting Epclusa. I have had no sex with my wife or even the slightest desire to have sex. I will not know if the Epclusa got rid of the Hep C for another 3 weeks when I have the first Blood Test. Currently, I am just wondering if I will ever feel normal again. I still feel like I am on the Epclusa. Talking to my doctor is a waste of time. She does not believe that Epclusa caused any of the problems that I am having."

• Aan...
• January 13, 2021

Sofosbuvir / velpatasvir for Hepatitis C "On my 2nd month with about 7 pills left. 3rd month was denied, but I had to reach out to Gilead, I think it was, and they gave me a coupon. Instead of the $3,700, which I could not pay, it will be 5 bucks for me, thank goodness it worked out. 27 years old, had hep C for about roughly 6 to 7 years. Was just tested 3 days ago, viral load is undetectable. My side effects: Extremely tired, so so so tired. Terrible headaches. Random weird sores. Ringing in ears. Random neck pain. Pain in lower back. Extreme hunger in the morning mixed with extreme sickness. Some diarrhea. Mood swings. Irritability. BRAIN FOG AND CONFUSION IS THE WORST, itchiness. I'm getting it all ways but in the end, it's worth it. Also, I get up at 2 am every day and work about a 10 to 11-hour shift and come home to my baby after and do not get to bed till 8 or 9, so I understand that is a lot on my body while fighting this also. Anyways, hopefully this helps someone stay strong and keep fighting!!"

• Gra...
• Taken for 1 to 6 months
• March 3, 2019

Sofosbuvir / velpatasvir for Hepatitis C "I just received the results from my final blood test, which is given 3 months after you finish Epclusa. The virus is gone, and I am cured of Hepatitis C! This medicine has given me my retirement back, and I am so grateful and blessed. Stick with it everyone, it's worth it!"

• Skp...
• June 5, 2019

Sofosbuvir / velpatasvir for Hepatitis C "I pray for all of you that the symptoms you feel go away. All of mine have stayed with me since 2017. I am damaged inside my body, inside my brain, and all of these doctors all say the same thing - there's no way Epclusa could have done this. I hope all of you get through this and your symptoms to go away, but mine stayed with me and I feel like I'm going crazy every day. Every day I feel more alive in my dreams than I do when I'm awake. Now I have constant pain in my knees, constant brain fog, everything hurts, I have no digestion, I have no colon that works anymore, it has messed everything up inside of me. It did get rid of hep C, but in my opinion, it messed me up. I would not tell anybody to take this medication. This medication is the same thing as Harvoni with just an extra medicine in it. I pray for all of you taking this medicine. If my hep C comes back, I will never try treatment again."

• Ang...
• Taken for 1 to 6 months
• August 12, 2019

Sofosbuvir / velpatasvir for Hepatitis C "Took my last dose of Epclusa in the morning. I have to say, the last week, I felt really tired, but if I had to do it all over again, I would. I will be going to my doctor in two weeks, and I will let everyone know the results. Before Epclusa, I was a very sick person, in and out of the hospital every month. Since I started this med, I have felt better and haven't been in the hospital. I feel much better, don't hesitate to take this medicine. Drink plenty of water and take a daily walk. I wish I had done this before my liver had been damaged. Happy with the treatment."

• MMO...
• Taken for 1 to 6 months
• July 9, 2025

Sofosbuvir / velpatasvir for Hepatitis C "I'm sitting here reading all your comments, and I am so sorry you guys are having all these symptoms. I have had hep C since I was 26, I'm 53 now. They thought I had liver cancer, and that scared the crap out of me. You don't want to ever go through that. I got an MRI, and it came back good. So I couldn't be happier. But I do have a blocked kidney. So if you have stones, try and do the right thing, because it's not fun. Anyways, I'm going on my 8th week, and I haven't noticed any side effects. I guess I'm lucky on that part. But I'm nervous. I hope this worked. It was hell getting it through my insurance. I wish everyone the best of luck. I guess I should know in about a month and a half."

• Hep...
• Taken for 1 to 6 months
• October 2, 2021

Sofosbuvir / velpatasvir for Hepatitis C "Finished taking Epclusa 1/3/2019. Almost two years later, I continue to have severe side effects. I had always been an extremely high-energy person, working and on the go for 16 plus hours a day. Since taking Epclusa, I continue to experience severe fatigue, memory loss (brain fog), and tinnitus. I have not been able to return to work since Epclusa. At this point, it appears that I traded a shorter but quality life with Hep C for quantity of life that's only watching it pass by. I'm continuing to search for answers for something to help restore my health. If I had known what the results would be, I would probably not have taken the Epclusa."

• Fra...
• Taken for 1 to 6 months
• September 11, 2019

Sofosbuvir / velpatasvir for Hepatitis C "I’m on my 34th day of taking Epclusa, a little over 4 weeks. I thought I was going to be sick in my first two weeks, but I wasn’t. Just some tiredness and headaches on and off. Please, don’t worry about Epclusa. For me, it’s been awesome. I wish I had done this forty years ago."

• trt...
• Taken for 1 to 6 months
• June 3, 2025

Sofosbuvir / velpatasvir for Hepatitis C "This is a follow-up posting (my first post was 6/2024 under TRT name, in which I narrated how I experienced absolutely no side effects during my treatment with Epclusa). I took Epclusa in Feb of 2024 and finished 3 months of treatment around the beginning of June 2024. I was tested then and again in 11/24 and just recently 5/2025. Every time, the test came back negative. I read so many reviews of the side effects such as brain fog, loss of appetite, rash, sleep problems, headaches, diarrhea. I can tell you all that I had never had those, not even 1 single time. I am currently 70 years old and I knew I had Hep C in my 30s, but I was so afraid of the interferon side effects (I read that some people lose hair during the treatment and some just gave up on completing interferon treatment), therefore, I waited until now, hoping that my liver does not develop cirrhosis. I wish everyone would be as fortunate as myself when taking Epclusa. Good luck to all of you."