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S-adenosylmethionine and Dizziness: What Users Say

Brand names: SAMe, Natrol SAMe, Adomet

Dizziness: mentioned by 5 users (10.6%)

Based on user experiences from 47 S-adenosylmethionine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 17.0%
nausea 14.9%
dizziness 10.6%
vomiting 8.5%
gi issues 6.4%
irritability 6.4%
panic attacks 6.4%
vivid dreams 6.4%

Reviews for S-adenosylmethionine

Commonly mentioned side effects
  • ban...
  • Taken for less than 1 month
  • May 1, 2020

For Depression "I’ve been on it for a week. I definitely feel like it’s lifted my depression some. I’ve been moderately to severely depressed for the last 3 years. I feel good, but the side effects are no joke. First day I took it, I felt dizzy, was sweating profusely, and vomited. The stomach pains were a 10 on a pain scale. I took it again the next day with plenty of water and on an empty stomach. The stomach pain was less, but still a solid 7. By day 3, the stomach pain was just uncomfortable. It’s been about a week now, but today I took it on an empty stomach and my stomach pains have been sharp for the last six hours and I feel nauseous almost all the time. The side effects are not worth working through so I’m going to switch to something else."

3 / 10
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86 Report
  • Not...
  • December 2, 2016

S-adenosylmethionine for Herbal Supplementation "I took the medicine for 2 days. One pill per day, on the third day I woke up fine, and fifteen minutes later I had severe abdominal pain, sweating enough to drench my shirt and head, disoriented, dizzy, and vomiting. I ended up in the ER and after blood work, an EKG, and a CT scan, they couldn't find anything. They could tell me what it wasn't. They sent me home with anti-nausea medicine. So two days go by and I realize I have not taken my supplement for arthritis, so I take it that afternoon, and by evening, I have severe abdominal pain, dizziness, and vomiting. Pretty sure it was the SAMe because I have felt fine since not taking any."

1 / 10
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126 Report
  • mma...
  • September 18, 2020

For Depression "I tried SAM-e a few years ago after my dad died. (200-400 mg morning huge glass of water) It was amazing, worked really quick, and I found the years of intermittent depression vanished (took for a few months). I weaned off and was fine until I started perimenopause symptoms, so I thought I would try again and see if it would help the lows and highs. It's only been a week, and it has stabilized them (also taking 300 mg magnesium). It's also helped my joint pain significantly, but it hasn't helped the anxiety, and I have bad bloating. The first few days, I was agitated, dizzy, and felt a bit manic, but I remember that from last time, and it settled now after a week. I am going to keep taking it for the joint pain and the depression, even though it hasn't helped the anxiety. I just hope the bloating calms down, as I feel like it puts pressure on my heart."

9 / 10
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27 Report
  • sb4...
  • March 27, 2014

For Depression "I had read up on this drug before using it, and multiple sources stated that it could help with depression. I was on it for about a week before I noticed any positive changes in my mood, so I can attest to its effectiveness against combating depression. The downside for this drug is that I experienced all of the 'less' severe symptoms, and I must say that they were pretty severe. On the second day of taking the drug, I experienced dizziness to the point that I fainted in public, and that very same day I had a horrible bout of nausea and vomiting. I vomited to the point that there was nothing left in my stomach, and I was just vomiting bile and blood from my raw throat. This works great for depression, but I'm going to use something else."

8 / 10
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45 Report
  • Rig...
  • Taken for less than 1 month
  • January 22, 2023

S-adenosylmethionine "I took SAMe for three days and ended up in the emergency room with dizziness so bad I couldn't safely walk. I also felt nauseous and vomited. This medication is not for me."

1 / 10
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14 Report

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