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Trulance User Reviews & Ratings (Page 4)

Trulance has an average rating of 6.1 out of 10 from a total of 271 reviews on Drugs.com. 47% of reviewers reported a positive experience, while 34% reported a negative experience.

Reviews for Trulance

  • Punkin
  • Taken for 1 to 6 months
  • September 18, 2018

For Chronic Idiopathic Constipation "I take it twice a week. Usually works within an hour and have relatively normal BM unless I am backed up. Then I get the diarrhea everyone complains about. Have to make sure you have fiber when taking and that seems to help decrease the bloating"

6 / 10
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30 Report
  • Doris...
  • Taken for less than 1 month
  • July 14, 2023

For Chronic Idiopathic Constipation "I took Trulance for constipation but didn't find it more effective than Miralax and I got a UTI after about 4 days. After about 8 days, I started having leg cramps and soreness even while taking electrolyte rehydration pills. I stopped taking it after 12 days."

2 / 10
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7 Report
  • Mbelle
  • October 17, 2017

For Chronic Idiopathic Constipation "I started taking this rx after years of severe constipation. I thought this was just a "woman" thing. I never knew IBS was also a constipation thing. I started out on Linzess and was moved to this drug as a cheaper alternative that was maybe better. So, 5 days into it I had nothing.....belly bloat, looked pregnant, and miserable. Day 6 came and let's say it was terrible, poo all over my bed as I slept. Day 7, poo all over the bed again. As I slept, severe diarrhea. So now I sleep with my first pair of diaper underpants. ????? I am 49, this is not a part of my life I wish to have at this point."

7 / 10
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33 Report

Frequently asked questions

  • Nita
  • Taken for less than 1 month
  • May 1, 2019

For Irritable Bowel Syndrome with Constipation "I’ve been suffering from IBS-C since 2009. Sometimes it’s so severe that I get stressed something more serious is going on. After 3 colonoscopies, CT-scan and taking Amitiza, Linzess I was prescribed Trulance along with Dicyclomine (for discomfort/pain) and IBGuard (by my 3rd Gastro). I’ve been taking it for 3 weeks I’m finally feeling better. I can even have a few consecutive days at a time without any pain at all. I’ve also been sticking to eating FODMAP free since 2015. It never worked before while on the other meds but everything seems to be working together now. I’m so much happier and comfortable in my clothes, when I go out, and in the bathroom than I was prior to Trulance. The only discomfort I’ve had while on it is acid-reflux. However, I’m not sure if its due to Trulance or the other meds I’m taking now. Good luck to other taking it!"

8 / 10
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27 Report
  • Sam...
  • August 23, 2017

For Chronic Idiopathic Constipation "After suffering for 2 years of bloating I had been using miralax which works slowly every day . Then the Dr say try this. Within 10 min I was in bathroom on and of for 2 hour while it was cleaning my system out. I had no bloating and no abdominal pain. I took the second dose today and it did same thing. In 10 min rolling thunder started in my stomach and cleaned out everything. I will try in a few more days then will ask Dr so far no more pain but I feel like it is a f18 fighter sound going thru my stomach for few hour after taking this.. Thanks goodness I tried it after work when I was home.. lol"

7 / 10
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33 Report

Are you taking this medicine?

  • Truly...
  • Taken for 1 to 6 months
  • September 8, 2018

For Chronic Idiopathic Constipation "I been on Trulance now for three months 3mg. At first use maybe like 4 days in I was going to quit because it was not doing much of anything. I was going to go back to my Miralax but my wife convinced me to hang in there so on the 5 day the heavens opened up"

10 / 10
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29 Report
  • jrzgi...
  • Taken for less than 1 month
  • February 20, 2023

For Chronic Idiopathic Constipation "I was prescribed a particularly unpleasant drug, which I took as directed: one 3mg pill. Shortly after ingestion, I was forced to rush to the bathroom. Three hours later, I had experienced diarrhea nine times in a row and was headed back for the tenth time. The experience was extremely uncomfortable, with cramping, bloating, and a persistent need to go. Despite being instructed to take the drug on Mondays, Wednesdays, and Fridays, I have no intention of taking it again on Friday."

4 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • June 25, 2018

For Chronic Idiopathic Constipation "Wrote a review previously. Still no side effects after taking for 3 months. Only thing I’ve noticed is weight gain - I was consistently 120 lbs for several years without change and since starting the medicine I am up to 126 without any other significant lifestyle changes. This medication somewhat improved frequency of BM but it’s hit or miss. Some days I still feel really backed up, others I have a well-formed movement. When taken with a probiotic this medication reduced my bloating signfiicantly. I would prefer not to be on long term medication anyway so I may consider discontinuing if I can’t drop the weight by increasing exercise. I need to find the root cause of my constipation instead of putting a band-aid on it. Make sure to get your ALS liver panel checked, as this medication can elevate those in some patients. Elevated ALS means your liver is inflamed/irritated."

6 / 10
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29 Report
  • KCano
  • Taken for less than 1 month
  • June 14, 2018

For Chronic Idiopathic Constipation "I had to share my experience. Opposite of most. I was afraid to even try this reading how much diarrhea people get. Took the first one in evening and prepared to rush to bathroom. Felt nothing. Next morning I had a very small hard bowel motion. Throughout the day I began to feel progressively more sick. Headache, exhausted, foggy, shaky. Almost a migraine type feeling. Took second dose that evening. Woke up the next morning feeling I was run over by a train. Horrible headache, shaking, pain in face behind eyes, totally wiped out. I was completely bloated, felt like I had a round balloon in my stomach. I had a hard time getting through the day and decided I needed to stop. It took a full 24 hours to feel better. Finally 36 hours later I have started pooping again and the headache is fading. This medicine was NOT for me. I have never had such serious side effects."

1 / 10
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29 Report
  • Nope
  • Taken for less than 1 month
  • November 4, 2019

For Chronic Idiopathic Constipation "I also have IBS. I have tried Trulance for about 10 days now. I have not had any diarrhea or relief other than a bit less pain in the abdomen. I have however had extreme ear pain, irritability, continued side pain, urination pain, dizziness and am more lethargic than before I started the terrible drug. I did not take any today and after being awake for 5 hours a sat down and fell right asleep in my recliner. I am awake now but looking forward to more sleep as I finish this post. I’m seeing my doctor tomorrow to have labs done to check my liver."

1 / 10
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23 Report
  • homer...
  • Taken for less than 1 month
  • April 11, 2018

For Irritable Bowel Syndrome with Constipation "I have had irritable bowel syndrome with constipation (IBS-C) for most of my life. I am a 56 year old man. I have had other problems since my early thirties which are side effects from eating and drinking anything that contains sugar. If I eat ketchup on fries, drink a soda or a glass of sweet tea, I am unable to keep my eyes open after 30 minutes and have to sleep off the symptoms. I started taking trulance last friday. I have had a bm every day since then. I no longer have side effects to sugar. I love this medicine!"

10 / 10
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29 Report
  • FOS
  • Taken for less than 1 month
  • April 14, 2019

For Chronic Idiopathic Constipation "Five days of taking this medication and not impressed. Had diarrhea twice for which I'm thankful after reading some of the reviews. All I'm getting from this medication is a stomach so bloated it would appear I'm in my 9th month of pregnancy and cramps that have me constantly running to the bathroom with absolutely no results. Glad this was a sample and I didn't pay any money."

1 / 10
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25 Report
  • Margie
  • Taken for 1 to 6 months
  • August 6, 2023

For Chronic Idiopathic Constipation "I've been on the drug for a month. I feel great. It has saved my life of misery. I just started my second month. I pray I continue to do so well. I've only had a few bouts of diarrhea in the beginning as my body was cleansing itself of old stool which always made me sick inside. I am so much better, I hope it continues."

10 / 10
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6 Report
  • Jakmak
  • Taken for less than 1 month
  • September 2, 2018

For Chronic Idiopathic Constipation "Was on both Lactolose & Relistor for over 2 years. Just started Trulance and what an amazing drug. Within an hour had a decent bowel movement without abdominal cramps, bloating & flatulance. 5 stars out of 5."

10 / 10
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27 Report
  • Luvey
  • Taken for 6 months to 1 year
  • January 3, 2021

For Irritable Bowel Syndrome with Constipation "I have had horrible, chronic constipation for 3 decades. Having a bowel movement was like having a baby with the result ended up with pelvic prolapse. Finally started Ametiza, took it for 5 years with still hard stools. Finally switched to Trulance in February. Have tried at various times but diarrhea is always the result. Covid has kept me home and so I can handle it. But we normally travel a lot and I CANNOT IMAGINE going out with uncontrollable diarrhea. I feel frustrated. Miralax gives me putrid smelling gas. Linzess is not an option. Wish Trulance comes in lower dose. May be that will reduce the diarrhea?"

7 / 10
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18 Report
  • Anonymous
  • September 14, 2017

For Chronic Idiopathic Constipation "I was so hopeful. Nothing else has worked. Took one pill. Painfully passed hard, mucus wrapped small stool, in pain for hours afterwards, but the real surprise is I had a delayed anaphylactic reaction. Faced swelled, lips swollen and painful, hives all around my mouth and sores in my mouth, throat swollen and red, trouble breathing. My face looked like it was deformed. Took Benedryl, called Trulance manufacturer the person there did not know the drug's source, they didn't know thehalf life, excretion/elimination time or way. Two days in and I am still battling the allergic reaction. If you tend to have allergic reactions take their "could have allergic response" seriously. Very angry."

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  • Anonymous
  • Taken for less than 1 month
  • January 13, 2018

For Chronic Idiopathic Constipation "After years of trying everything on the market, including Linzess and Amitiza, I was given samples. It has been working great! I do have days of loose stools but the alternative to me is worse. I go everyday and my bloating is gone! No cramping, headache, bloating. I would recommend this medication. I'm not sure the cost tho, I haven't purchased from pharmacy yet. I hope it is not too expensive! Drug companies need to know that what we go thru is awful and these drugs should be covered by insurance!"

9 / 10
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28 Report
  • Anonymous
  • Taken for 1 to 2 years
  • March 29, 2018

For Irritable Bowel Syndrome with Constipation "I began Trulance about a year and a half ago, soon after it was released onto the market. For years I had taken a probiotic, and my pain was worse. I did a Miralax regiment for several months, with no luck. My doctor then put me on Linzess, which was the most miserable I’ve ever been in my life. I was prescribed Trulance and have had very few problems since. If I maintain a diet and eating schedule, I have a regular BM every morning. I rarely have pain, if I do, it is caused by gas of not taking my pill on time. Trulance has drastically improved my confidence as I reclaimed my health."

9 / 10
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26 Report
  • Cant...
  • Taken for 1 to 6 months
  • February 18, 2019

For Chronic Idiopathic Constipation "I’ve used trulance 3 mg for about 3 months now It worked really well at first but now it’s not working so good My ammonia level in my blood is very high and I thought I’d found the miracle drug .. Quit working after one month of taking I’m moving on to something else This medicine has crazy side effects as well I would not recommend this medicine"

3 / 10
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23 Report
  • Christy
  • Taken for 6 months to 1 year
  • February 28, 2022

For Chronic Idiopathic Constipation "I have a barrel full of gastro diseases. I was prescribed Trulance for chronic constipation and gastroparesis. I don't take it every day, but when I do, I have a bowel movement within 2 hours and it's done within a few hours (I take it when I get home from work). I have no side effects except for some diarrhea mixed with solids. Do note that if you do not drink liquids when you take Trulance, you probably won't have a BM. Trulance works by drawing liquid into your small intestine. If you're already dehydrated, Trulance more than likely won't work. If you're feeling "sick" after taking Trulance, again, it is more than likely because of dehydration. Make sure you can keep liquids down prior to taking, during, and after taking Trulance, that's how Trulance works."

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  • Britt...
  • Taken for less than 1 month
  • May 31, 2018

For Chronic Idiopathic Constipation "I have struggled with chronic constipation my entire life. I am a 29 year old female and my gastro dr prescribed me Trulance over 2 weeks ago. For the last 11 yrs I have tried everything including amitiza, linzess, bag enemas, miralax, dulcolax, etc. None worked. I was diagnosed with gastroparesis, celiac disease and Chronic constipation. My entire colon is slow transit. I was really optimistic when I saw other reviews saying within 2 hours they were having diarrhea. I was surprised some people gave up taking this drug due to the diarrhea. I have a 4yo son I don't have time to feel awful anymore. I am so disappointed. Over 2 weeks on Trulance and nothing. Just bloating and gas. I plan on seeing my dr and asking about removing some of my colon. I am desperate to stop feeling toxic. I am glad this medication works for some people. I would recommend to at least give it a try you could have better results than what I did. Good luck!"

1 / 10
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25 Report
  • Trinity
  • Taken for 1 to 6 months
  • November 18, 2018

For Irritable Bowel Syndrome with Constipation "My doctor gave me a month trial of Trulance hoping that it would work better for me. It worked within 3 0mins of taking it. I noticed a difference when I took it without food vs with food. With food, I would be running to the bathroom about 17 times before the diarrhea stopped. My rectum would be very painful afterwards. Taking Trulance without food was better, I'd go 4 times with 1 regular stool then the rest runny/explosive diarrhea. I did have side effects. I would get dizzy spells every day that I took the pill. I also started getting blurry vision, no matter how much I blinked or rubbed my eyes. The blurriness wouldn't go away. Lastly, it made me gain weight. My diet has been the same for months except my sweets have been cut down. I go to the gym for 1 hour 3 times a week. At the end of my monthly trial, I gained almost 11lbs! I have never gained that much weight that fast. Before Trulance, I was actually losing weight. I will happily go back to Linzess."

3 / 10
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23 Report
  • johnr...
  • Taken for 1 to 6 months
  • November 25, 2017

For Chronic Idiopathic Constipation "Started using trulance not so long ago, hoped it will help me before I leave for a vacation. It does! after about a week I started going almost every day and I feel so much better. Makes me happy iIdon't need to worry about this problem anymore."

9 / 10
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26 Report
  • Bummed
  • Taken for less than 1 month
  • May 17, 2019

For Chronic Idiopathic Constipation "On Trulance I had nothing but daily pain after three weeks usage. No improvement at all. Even tried enemas to get things going and...nada. Also I have been binge eating and gaining lots of weight. Going to discontinue. I hope others have more success."

1 / 10
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21 Report
  • Dcumm...
  • Taken for less than 1 month
  • May 23, 2017

For Chronic Idiopathic Constipation "The first 3 days I experienced diarrhea within 2 hours of taking Trulance 3mg tablet. I continued taking it and I am now 15 days in and have to take an enema for constipation. Seems that Trulance is no longer effective in my system. I am very disappointed!"

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27 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.