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Actos and Fatigue: What Users Say

Fatigue: mentioned by 3 users (7.5%)

Based on user experiences from 40 Actos reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

swelling 27.5%
weight gain 25.0%
fatigue 7.5%

Reviews for Actos

Commonly mentioned side effects
  • Tbe...
  • July 3, 2013

For Type 2 Diabetes "I am 66 years old and have been on Actos for over five years, taking 45mg. Lately, I have experienced shortness of breath, swelling of ankles and feet, weight gain, anemia, and fatigue. My primary physician ordered an echocardiogram and a lung function test, and they both indicated my heart and lungs were fine. The doctor attributed the issues to my taking Actos and immediately took me off the medication. He replaced it with Tradjenta (5mg) and asked me to monitor my blood sugar levels three times a day during the transition. I have been off Actos for 24 hours and feel better already. I know that sounds impossible, but I believe it may have been the cause of my recent health issues."

6 / 10
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155 Report
  • epi...
  • January 25, 2011

For Type 2 Diabetes "Took 30 mg Actos for 8 or so months, was very happy with it at first. It did lower my numbers, but... I had so many bad side effects. Weight gain, chronic fatigue, swelling, urgent need to urinate, watery eyes, and pain. I could barely get up my steps. I stopped taking this medicine myself, and I feel as if I have been raised from the dead."

1 / 10
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154 Report
  • Dav...
  • Taken for less than 1 month
  • September 18, 2021

For Type 2 Diabetes "I have been taking 30 mg for 2 1/2 weeks now. I have had migraine headaches, blurred vision, dizziness, loss of balance, nausea, and stomach pain. Severe fatigue to the point I have spent 12 out of the past 14 days in bed or on the couch, unable to do normal daily functions. I have also gained 2 lbs. That may not sound like much, but when you take into account that I only eat half of a small homemade ham sandwich or equivalent per meal, that's a lot. 2 weeks ago I weighed 148 lbs, I now weigh 150 lbs and have been eating less than before starting Actos."

1 / 10
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9 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.