Pimavanserin for Parkinson's Disease Psychosis User Reviews

• Dee...
• Taken for 2 to 5 years
• August 16, 2018

"My husband began taking Nuplazid two years ago (when it first went on the market). Before that, his night terrors/hallucinations were horrific and becoming dangerous to himself and me. He acted out dreams in which he believed he was in a war, that people were trying to kill him and his family, etc. Once on Nuplazid, these extreme episodes ended. He now has much milder episodes-seeing family members in the room who aren't there, etc., but nothing that results in dangerous movements, aggressiveness, etc. Plus, he comes out of the episodes much easier than before. Most of the side effects listed for Nuplazid were problems he already experienced before being on the drug; they have not worsened since."

• Amb...
• Taken for 1 to 2 years
• July 28, 2020

"My husband had bad hallucinations and delusions. He would see people around him, in his bed, see water and insects all over. When he started taking Nuplazid one and a half years ago, all symptoms subsided. He had no episodes of hallucinations or delusions. It was a miracle drug for him. I shared the experience with my care group. They asked their doctor about it and got the prescription. They also had a positive effect."

• Kat...
• March 22, 2019

"My 79-year-old mother has Parkinson’s and Lewy Body Dementia. She experiences a lot of hallucinations that totally control her life. We finally tried Nuplazid. She started taking it Tuesday. She has taken only 3 pills. We are having her taken off immediately. OMG – it had an immediate negative impact on her. Hallucinating even more. Became very paranoid. (She thought she was being arrested.) She was crying and severely depressed. Worst of all, her walking got even worse. She was hunched all the way over and could barely move. Very confused. We have 2 different cameras on her to make sure she is okay, the cameras have been a lifesaver. She became so weak she couldn’t get herself in bed. Her legs were just hanging off the bed. We were able to call her assisted living to have them help her. I’ve never seen a drug have a negative impact so quickly. Waiting for the drug to leave her system. It has a 57-hour half-life, so we are hoping it’s out of her system in 5 days."

• BAD...
• October 19, 2021

"My dear friend, out of desperation, wanted to try Nuplazid in hopes of feeling better. His neurologist put him on it. He was a mess after about 2 weeks on the drug. He started to have horrific eyes-open hallucinations, he saw bloody heads, heads coming out of holes in the floor, strange people moving about. The doctor was aware of these things but kept him on it for 9 months. The final thing was he was seeing children without hands, and he had left cookies all over for them. His family did not stop this doctor, so finally, an RN took charge, and this doctor stopped this poison, Nuplazid. Mental damage was done. He suffered these sightings now in his dreams. These were the same hallucinations now in dreams. What a miserable way to live. Just writing this for other people to know how dangerous this Nuplazid can be. I applaud the family members of the folks with Parkinson's when they observe their loved ones and not just listen to a doctor pushing this drug."

• Mea...
• Taken for less than 1 month
• December 18, 2021

"My husband has had Parkinson's for close to ten years. Out of the blue, he started having illusions and delusions, thinking I was working with people to trick him and other bizarre things. He thought I was kidnapping people, and on and on, keeping me awake at night talking about all the bad things I was doing and saying he wanted to die. After three weeks with no relief, and out of desperation, I asked his doctor to prescribe Nuplazid. It took a lot of effort to get it, but it has helped tremendously. After a week and a half, I could see the change. He has been on it almost four weeks now. I literally feel it has been a lifesaver. No side effects, and I have my sweet husband back. He is on a low dose. I will continue to watch him closely for side effects, but for now, I am very grateful."

• dav...
• March 19, 2019

"Took Nuplazid for Parkinson's disease and dementia. It is terrible. I'm having hallucinations, trouble eating food, trouble swallowing, and had a blood clot in my lung. I became confused and was talking gibberish. I tried wrapping a canvas belt around an armchair. Who knows why? My wife tried to get me to stop after 30 minutes. I became so confused."

• DBa...
• Taken for 2 to 5 years
• February 19, 2021

"My husband was having the kinds of nightmare hallucinations that another person described-being in a war; people trying to attack his family. He was admitted to a psychiatric unit at exactly the point in time that Nuplazid came on the market, so the hospital had time to see if it would help him. It has been the same kind of miracle drug described before-didn't stop hallucinations altogether, decreased their frequency, and altered the kind of hallucinations so that he was seeing family in the room and couldn't understand why they wouldn't answer him when he spoke to them. He is in a nursing home and is still having those types of hallucinations, but is aware that they are hallucinations once he comes out of them. He was recently put on Provigil; I'm concerned that his hallucinations seem to have increased in length and become more intense in how real they seem."

• Jen...
• June 24, 2020

"My brother tried this Nuplazid for his Parkinson's. Hallucinations increased, resulting in a major event that included police intervention. Removed the patch. He returned to his 'normal.' Beware!!!"

• PDf...
• Taken for 1 to 6 months
• November 20, 2021

"My dad, who has PD, tried this drug, and hallucinations got worse and more threatening. Isn't it ironic that a medication approved by the FDA for hallucinations can cause hallucinations?"

• Anonymous
• January 30, 2022

"Miracle drug. My husband would not be able to live at home without its positive effect on significantly reducing hallucinations and delusions."

• Jan...
• Taken for 6 months to 1 year
• March 11, 2022

"My mother was placed on Nuplazid after trying a few other drugs that only made her worse. It took a while, but slowly her hallucinations greatly decreased."

• Ben...
• Taken for 1 to 6 months
• September 22, 2021

"Minimal relief, if any, from Parkinson hallucinations after three months of use."

• Joa...
• Taken for less than 1 month
• October 20, 2022

"My husband became extremely confused, could not walk, was weak, and began to have many hallucinations with the drug Nuplazid 34 mg. And he also started to babble and seemed out of it."