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Orlistat and Oily Skin: What Users Say

Brand names: Xenical, Alli

Oily skin: mentioned by 6 users (1.5%)

Based on user experiences from 400 Orlistat reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 11.0%
gas 5.0%
upset stomach 5.0%
constipation 3.3%
bloating 1.8%
oily skin 1.5%
cramps 1.3%
headaches 1.3%
liver damage 1.0%
bowel movements 0.8%

Reviews for Orlistat

Commonly mentioned side effects
  • Chr...
  • Taken for 1 to 6 months
  • July 19, 2019

Orlistat for Weight Loss (Obesity/Overweight) "When I started taking this drug, I was 235 lbs, and in a matter of 4 weeks, my weight came down to 220 lbs! 15 lbs in a month!! I did not even exercise, so imagine how much more is possible if I did. One thing to be careful with is leakage. It makes it easy to leak orange fats when farting, so be careful with that since it’s oily!"

9 / 10
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144 Report
  • Anonymous
  • November 16, 2018

Orlistat for Weight Loss (Obesity/Overweight) "I started taking Xenical (Orlistat) almost a week ago. I'm 5.3 and currently weigh 162 lbs. I gained about 30 pounds after 3 and a half years of using Mirena IUD, that's why I started taking Orlistat, because nothing was working, it seemed as if my metabolism had been shut down. I eat about 1200 calories every day, I work out 3 days a week, and I get around 6000 or more steps a day. So for the first 3 days, I had no oily side effects, but on the fourth day, that's when it really kicked in for me. So far, I haven't really lost any weight, if anything, I've gained about 2 pounds, but I'm not sure if that's because I've been working out and my body's retaining more water. I also have my monthly visitor, so I'm not quite sure yet. But I will keep you all updated after 2 weeks."

7 / 10
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30 Report
  • ora...
  • Taken for less than 1 month
  • July 31, 2019

For Weight Loss (Obesity/Overweight) "I'm taking Alli, and it's only been a week, during which I haven't been able to exercise because I'm sick, so I'm not ready to rate it yet. However, I've been enjoying the more off-putting side effect of oily, orange... stuff? Exiting my body? It only really happens when I eat something high in fat, like chocolate, and I knew beforehand that that might exacerbate that particular side effect. Avoid high-fat foods as much as possible while taking this, wear a panty liner during the day and an overnight pad at night. That's not just a 'girl' thing. Anyone can buy pads, and if you don't while taking orlistat, you better buy some backup underwear in bulk. It may not be pretty, but neither is weight loss. I put on about 60 lbs over the course of a couple of years for no real reason (stress? medication? those are the two remaining reasons), and this is honestly my last resort. I already eat fairly healthy, and I exercise a few days a week. If this helps even a little, I'll consider it a miracle."

7 / 10
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16 Report

Frequently asked questions

  • Tee...
  • Taken for less than 1 month
  • November 21, 2017

For Weight Loss (Obesity/Overweight) "Started taking Orlistat 120 mg one week ago after reading many reviews on here. I was a bit skeptical as I don't have a huge amount of weight to lose. Weighed myself this morning and have lost 4 lbs. My clothes already feel much looser. I have followed a strict low-fat/calorie diet and hadn't had any oily side effects until... I had about 10 g of grated cheddar with my dinner last night and felt the consequences this morning. Nothing major, but now I know cheese is a NO GO!!! Not a bad word to say so far ☺ Good luck to everyone else too x"

9 / 10
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14 Report
  • Nin...
  • Taken for less than 1 month
  • June 6, 2014

For Weight Loss (Obesity/Overweight) "I started taking Xenical 2 weeks ago. Been hard to stick to a healthy diet. I've seen it all, the oily, etc. But have lost 4 pounds. I have managed to eat healthier the past 2 days. Am going to stick to eating healthy. I need to lose at least 2 stones in the next 3 months."

7 / 10
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19 Report
  • Bun...
  • August 29, 2017

For Weight Loss (Obesity/Overweight) "I had a very overweight friend whose doctor put her on orlistat, it really did work for her. She said that if she ate a fatty meal, then at some point she would see that greasy, oily leakage that the orlistat stopped from being absorbed into her body. She did start to eat healthier and lost more weight through that and the knowledge that if she fancied something a bit naughty food-wise, she had the orlistat to help. I do worry it's a bit of a comfort blanket for her, as she doesn't believe she can lose the weight without having her orlistat to hand if needed. She looks pretty good now, but still relies on her orlistat for 'bad days.'"

8 / 10
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13 Report

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