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User Reviews for Ondansetron to treat Nausea/Vomiting, Chemotherapy Induced

Also known as: Zofran, Zofran ODT, Zuplenz

Ondansetron has an average rating of 7.5 out of 10 from a total of 15 ratings for the treatment of Nausea/Vomiting, Chemotherapy Induced. 73% of reviewers reported a positive effect, while 20% reported a negative effect.

Ondansetron Rating Summary

7.5/10 average rating

15 ratings from 15 user reviews.

Compare all 38 medications used in the treatment of Nausea/Vomiting, Chemotherapy Induced.

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47%
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13%
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13%
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7%
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Reviews for Ondansetron

Anonymous March 16, 2010

Zofran (ondansetron): “My Mother was diagnosed with Ovarian cancer and had to undergo months of chemotherapy which caused her to be severely sick (she was 69 at the time of diagnosis). The medication for sickness that the hospital gave her didn't work, and she still vomited and felt drained etc from both the vomiting and the chemotherapy. I went to my GP (I'm English) and asked him if there was anything which he could prescribed to help her as it was terrible seeing her going through this, and he prescribed Zofran. I cannot praise this medication enough, within moments of her taking it, her sickness subsided and she continued through her chemotherapy taking only the Zofram and she was never sick again!!”

10 / 10
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swinlin · Taken for 5 to 10 years September 13, 2020

Zofran (ondansetron): “I went through pure nightmare during chemo for my Triple Negative BC in 2015. Nausea is an understatement. My oncologist told me that I was the worst patient she ever had with nausea. This is a woman who was practicing in the 70's when they still treated with mercury. I cannot tell you how many nausea medications I was prescribed. Zofran was by far the BEST medication at relieving my symptoms. 5 years later I still cannot 'handle' any kind of nausea. I have an 'emergency' prescription that I have with me 24/7. I only need it maybe twice a year, but it is still the Magic Bullet that relieves any nausea/vomiting I may have. I HIGHLY RECOMMEND THIS MEDICATION!!!”

10 / 10
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DaMaFia6iX · Taken for 2 to 5 years July 5, 2014

Zofran (ondansetron): “Going through chemotherapy for ALL for 3 years, and I've tried EVERY available CNIV that I could get when I was doing my chemotherapy. Zofran by far was the best for me specifically the sublingual (melt under the tongue) it also has a cherry taste to it and the taste of it gives me an almost instantaneously feeling of the symptoms being not as bad and then as it finally melts it greatly reduces the symptom if not completely stops them. Sometimes unfortunately there's times that even though it reduced symptoms that the CNIV was just stronger and I'd still not feel to well and still have CNIV but it did at least help and make it more tolerable when it didn't completely take it away.”

10 / 10
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NormT · Taken for 1 to 6 months April 3, 2018

Zofran (ondansetron): “I'm one of those people that would rather be in pain than nauseous, so when I started chemotherapy I knew I was in for a ride. I was given a cocktail of meds right before chemo and then Decadron and Zofran for a couple of days after for allergic reaction and nausea. For the times after that "as needed" I have Zofran & Compazine for nausea and Ativan for "anticipatory nausea". I guess the Ativan would help some commenters in this thread who actually get sick from thinking about getting sick. It made me too drowsy so I was left with the Compazine and Zofran. I found the Zofran to be by far the most effective; I take one 4mg tablet as soon as I start feeling queasy and within 10-15 minutes I am fine - I'm even able to eat. Thankfully my insurance covers it as it is a little more expensive than some meds for nausea but to me it's worth not vomiting. I recommend this medication highly.”

9 / 10
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omaralim July 21, 2008

“My mum started taking Zofran when she was on Folfox-4 Protocol (5-FU and Oxaliplatin) for the treatment of Stage IV colorectal cancer. Zofran was instrumental in removing the nausea and vomiting side effects that usually accompanies this treatment. Mum rarely had any vomiting or nausea attacks while she was using Zofran. The only side effect was slight chapping on the lips which was easily treated by using topical creams.”

10 / 10
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Anonymous · Taken for 6 months to 1 year October 21, 2012

Zofran (ondansetron): “Overall, it has been the best anti-emetic available for chemotherapy induced nausea and vomiting. The downfall is gastric slowdown-- which can become more pronounced if on vinca alkaloid chemo or opioids.”

9 / 10
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Zofran saved me during cancer. May 1, 2016

Zofran (ondansetron): “I had a very long treatment time, 3Xweek, 2 8 hr. sessions with three types of chemo radiation. It was every 3rd week, Wed, Thur, & Fri. Wed/Thur were 8 hr. sessions, Fri, 4 hrs. I was constantly vomiting, morning, noon and night. I took this from the get go, but after about my 2nd session, I threw up a lot in the mornings, or if I coughed too hard even. I know it would have been SO much worse without the Zofran. I think with the amount of treatment I had, both chemo and radiation, to both my chest and to my brain that I was VERY lucky I wasn't more sick, and frankly, I'm lucky to be here at all. Thank you Cancer Treatment center and of course, thank you God!”

8 / 10
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Frequently asked questions

Susan from NC · Taken for 1 to 6 months August 1, 2016

Zofran (ondansetron): “Could not tolerate this drug during chemo rx Hated it prescribed for thee cycles of my red devil chemo treatment It caused paranoia constipation which caused increased vomiting and also probably added to the chemonesia issues Zophran Was replaced by Emend and i had 180 degree different drug and had no issues whatsoever Zophran interferes with serotonin in the brain”

1 / 10
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Anonymous · Taken for less than 1 month June 3, 2019

“I just discovered I will not be taking this pill anymore!!! I was taking it for anti nausea for chemo, three weeks ago I started on chemo, now I'm horribly bloated, for the past week, so bloated I look like I'm pregnant, horrible gas horrible constipation I am not taking this pill ever again!! I am so bloated and I I'm so swollen everywhere, they even checked me for blood clots Thursday because I was so swollen, my ankles are swollen horribly bad my face is swollen horribly bad and now after a week I am discovering is from this stupid anti-nausea pill!!”

1 / 10
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lw · Taken for 5 to 10 years March 8, 2019

Zofran ODT (ondansetron): “The brand Zofran worked perfect. Generics (Mylan, Rising, Glenmark) began coming out 2 years later. These made sicker & caused headaches. Zofran contains .03 mg aspartame. Generics have .51 mg. Naturally insurance won't cover Zofran. I'm just glad I got it when I first started chemo when sickest.”

10 / 10
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Maddoxmed · Taken for 1 to 6 months December 31, 2019

“Horrible drug. Been on chemo and this was my 4th cycle and you can have a severe reaction to ondansetron. I thought I was going to b the end of me. Apparently you can get sensitive to this medicine as time goes by. Thank fully I'm here to tell the story. This drug should be taken very carefully by doctors. Next time for my chemo I expect no ondasentron for me!”

1 / 10
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Marilyn · Taken for 1 to 6 months April 29, 2021

“Had Chemo for breast cancer. Very effective drug, took care of my nausea immediately for the whole day. Down side is that it was very constipating for me. I already am chronically constipated and this drug made it worst. Had to take laxative to keep myself going.”

10 / 10
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Medulloman · Taken for 2 to 5 years June 29, 2013

Zofran (ondansetron): “A cancer patients best friend. I find it horribly constipating so I always take it with a stool softener.”

8 / 10
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Trish one of many December 7, 2015

Zofran (ondansetron): “Sadly, oral Zofran (or at least the generic of it) was not enough to combat my nausea while on GDP. However intravenous zofran along with hydration did help.”

5 / 10
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silk J. May 5, 2015

Zofran ODT (ondansetron): “Very good for nausea and shaking.”

10 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.

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