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Macrodantin and Headaches: What Users Say

Headaches: mentioned by 7 users (14.6%)

Based on user experiences from 48 Macrodantin reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

chills 16.7%
headaches 14.6%
nausea 14.6%
diarrhea 12.5%
dizziness 12.5%
fever 12.5%
chest pain 8.3%
loss of appetite 8.3%
tiredness 8.3%
vomiting 8.3%

Reviews for Macrodantin

Commonly mentioned side effects
  • sic...
  • September 23, 2014

For Urinary Tract Infection "After having a lot of urine infections for the past year, I am now back on Macrodantin 50 mg, 4 times a day for 7 days. Makes me feel yak, headaches, keeps me awake, slightly dizzy, feel tired a lot. Then doctor wants me to take a low dose of it for 6 weeks. Will keep you posted if it actually works this time. I have my doubts."

5 / 10
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36 Report
  • Joe...
  • Taken for less than 1 month
  • November 8, 2020

For Urinary Tract Infection "Was prescribed Macrodantin for UTI. Was extremely ill from day one with a headache, pressure in the left ear, muscle pain, back pain, and a general illness feeling. Was originally prescribed 5 days of 100 mg twice a day. Day 2/3 I couldn't bear it any longer and contacted the doctor to change it, he insisted I stay on it and changed it to 50 mg x 4 times a day. Gave up on day 3/4 as I couldn't take the side effects and low mood any longer. Still not feeling great on day 7, and the ear still feels full."

5 / 10
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15 Report
  • Hil...
  • Taken for less than 1 month
  • March 16, 2021

For Urinary Tract Infection "Scary experience. I started to get very ill a few hours after starting the medication, nausea, headache, vomiting, and sensitivity to light. Two days later, a GP told me I may have the flu. I went home, went to bed. So weak, low fever, chills, could not get warm, still vomiting, horrendous headache. A few days feeling the same, I noticed a rash on my body. Went to the emergency department by ambulance. The antibiotic had caused acute liver failure. I had been on day five of a seven-day course. Lucky enough, the doctor in the hospital put the connection together, and the medication was stopped. It took a few months to recover from the fatigue, especially, but I'm lucky to be alive also. Another few days at home alone, I would probably have passed out. I was delirious most days, so they were blurry and confusing. No more Macrodantin for me. Even have an emergency bracelet if I need to travel outside Ireland."

1 / 10
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8 Report

Frequently asked questions

  • Lee...
  • October 8, 2017

For Prevention of Bladder infection "Macrodantin was prescribed to me to prevent UTI. I only have to take one when needed. During one month, I got four fever attacks with chills, headaches, and muscle cramps. Very much like flu symptoms. It goes on for 2 days, then I am fine again. Eventually, I realized that it might be this medication since I took one on a Friday evening, and the next day when I woke up, I got these horrible symptoms again. I read about the side effects and realized that this might be the cause."

7 / 10
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13 Report
  • Gan...
  • Taken for less than 1 month
  • August 10, 2020

For Bladder Infection "Prescribed Macrodantin for a mild bladder infection. 2 doses of 100 mg per day. I take them after a meal. The only side effect I have is a pounding headache. I've 1 tablet left to take, and I feel like my bladder infection is gone too. Still a dull ache at the bottom of my back, but that could be unrelated. The headache is real though."

5 / 10
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8 Report

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  • Zar...
  • Taken for less than 1 month
  • April 5, 2018

For Urinary Tract Infection "I'm currently taking these twice a day for UTI. I'm on day 5, and I can't seem to sleep, it takes me hours. My chest keeps getting tight when breathing, and I'm coughing a lot, with a constant headache today. I haven't eaten a meal or breakfast since 3 days ago because I have lost my appetite. I don't even feel slightly hungry. I wish these 2 days I have left on these tablets would hurry up because I want to go to sleep and eat a meal. They have gotten rid of my UTI, my urine has also gone bright yellow as well."

5 / 10
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8 Report
  • los...
  • November 30, 2020

For Urinary Tract Infection "I was prescribed 50 mg Macrodantin capsules to be used over the course of 7 days for treatment of a UTI. Let me tell you right now that this medicine not only doesn't work and that I still have a UTI after completing the course; the side effects were like nothing I had ever felt before, and my infection actually progressed to a kidney infection. First off, I started to feel nauseous while taking this medicine and thought that it would be alright after a few days. However, by day 3, I was in agony with abdominal pain, chest pain, lower back pain, fever, and chills. The nausea was also still there. I decided to call my doctor, and they advised that I finish my 7-day course and then call back if symptoms did not stop by day 7. By day 7, I still had a UTI, as well as chest pain, abdominal pain, headaches, nausea, dizziness, fever, and chills, all of which only started to happen once I took these antibiotics. This medicine may as well be a placebo."

1 / 10
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8 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.