Neratinib and Vomiting: What Users Say

• Mis...
• Taken for 1 to 6 months
• October 18, 2018

Neratinib for Breast Cancer, Adjuvant "Was determined to continue with Nerlynx despite severe diarrhea, nausea, vomiting, and total loss of appetite. Most side effects stopped at the three-month mark, thankfully. Lost 10 kg in that three months (needed to lose weight)."

• Que...
• February 11, 2018

For Breast Cancer, Adjuvant "♡☆PART ONE☆♡ I started neratinib (Nerlynx) on 1/26/18 (Friday). -About 8 hours after taking my first dose of neratinib (six 40 mg tablets) with loperamide (two 2 mg capsules), I had a headache and stomach ache. -About 10 hours after my first dose, I made my first visit with my arch-nemesis (the toilet/commode/potty). -I continued as instructed to take two capsules of loperamide three times daily. -By the time I took my second dose (1/27/18 Saturday), I had become the vulnerable one to my arch-nemesis with at least 15 encounters. -Now the arch-nemesis and I are becoming friends as I am visiting 20-25 times a day with 7-8 timed visits. I had also vomited about 6 times as well (1/28/18 Sunday). -With no sleep, vomiting 5 times and over 25 mini vacations to the bathroom, my body couldn't take any more showdowns. I made an appointment with my oncologist for the next day (1/29/18 Monday) while still continuing to take the loperamide as directed."

• Gem...
• Taken for less than 1 month
• September 29, 2019

For Breast Cancer, Adjuvant "I've been on Nerlynx for 10 days, started by taking it alongside the recommended budesonide and loperamide, but got constipated, burning, bloated stomach, shortness of breath, fatigue, and insomnia, and severe vomiting. Stopped taking the support tablets 3 days ago, minor improvements, no longer vomiting, but still have not had bowel movements! I may need help for constipation while on Nerlynx!"