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Neratinib and Nausea: What Users Say

Brand names: Nerlynx

Nausea: mentioned by 4 users (14.8%)

Based on user experiences from 27 Neratinib reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 63.0%
upset stomach 18.5%
fatigue 14.8%
nausea 14.8%
constipation 11.1%
headaches 11.1%
tiredness 11.1%
vomiting 11.1%

Reviews for Neratinib

Commonly mentioned side effects
  • Tin...
  • Taken for less than 1 month
  • July 15, 2018

Neratinib for Breast Cancer, Adjuvant "The jury is still out for me on this new adjuvant treatment. I finished Herceptin and Perjeta on June 28th and started Nerlynx July 7. The first 24 hours were manageable with diarrhea, but we’ve been off to the races since then. 12-15 times a day in the restroom. I’m taking the prescription strength Imodium per the directions, but I see many here take it every two hours. I’m calling the oncologist today to ask if I can take it that frequently because if not, I will have to stop taking Nerlynx. It is disrupting my life, and the nausea and belching aren’t helping either."

6 / 10
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23 Report
  • Mis...
  • Taken for 1 to 6 months
  • October 18, 2018

Neratinib for Breast Cancer, Adjuvant "Was determined to continue with Nerlynx despite severe diarrhea, nausea, vomiting, and total loss of appetite. Most side effects stopped at the three-month mark, thankfully. Lost 10 kg in that three months (needed to lose weight)."

7 / 10
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19 Report
  • que...
  • February 2, 2018

Neratinib for Breast Cancer, Adjuvant "I have taken Nerlynx (Neratinib) for 1 week. Today, the 7th day, I'm going back to the Imodium every 6 hrs. Within the first 8 hours, my stomach was cramping, diarrhea, and nauseous. After the 3rd day of diarrhea more than 15 times a day, my oncologist increased the Imodium to every 2 hours. I'm still tired but have high hopes in continuing for the full 12 months."

8 / 10
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13 Report

Frequently asked questions

  • del...
  • Taken for 6 months to 1 year
  • October 10, 2019

For Breast Cancer, Adjuvant "I started this drug, neratinib, in February of 2019. Of course, I had the same issues with diarrhea like everyone and went on a strict course of three doses a day of two each Imodium. The first two months were terrible, and I could not really find anything online to help. In the third to fifth months, the diarrhea was almost gone, and that was a blessing. From July to now, which is October 2019, the diarrhea has returned with a vengeance. My oncologist told me that most of his patients have stopped taking it. I am going to stick it out because I trust him, and if this helps me, then it will be worth it. I actually gained weight! I feel pretty lousy most every day, like I have the flu, and I get skitzed out that it might be more cancer because I do worry. I am nauseated a lot, so I seem to eat more. I am tired of cleaning my toilets...that is for sure!"

6 / 10
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8 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.