Skip to main content

Naloxone / pentazocine User Reviews & Ratings

Naloxone / pentazocine has an average rating of 7.4 out of 10 from a total of 26 reviews on Drugs.com. 69% of reviewers reported a positive experience, while 23% reported a negative experience.

Write a review

Reviews for Naloxone / pentazocine

  • Anonymous
  • August 29, 2010

Naloxone / pentazocine for Pain "I deal with chronic back and leg pain due to a ruptured disc and bulging disc above and below, three ruptured discs that were fused via surgery. I have been on opiates (hydrocodone, morphine, oxycet) for four years and finally got sick of the side effects and physical dependency these drugs create. The dependency and withdrawal finally got worse than the pain that these drugs released. I detoxed cold turkey off of them for two weeks and then decided to try this medicine. I have been on it for about a month and it has worked wonders. Very few side effects and sweet pain relief. I do not have to be on this medicine every waking moment and I can even go days without needing any. So far this has become the answer I have been searching for."

9 / 10
Was this helpful?YesNo
74 Report
  • icy...
  • July 20, 2010

Naloxone / pentazocine for Pain "I have been taking Talwin NX for about 3 years now. I have two fractures in my mid and lower back. The first doctor I saw for this condition had me on Vicodin 10 mg. He had me on 56 pills a week. After a while, my weekly appointments stopped being about pain and started to be about getting that script filled. I finally woke up to the fact that I was addicted to these pills. It really scared me. I went to my primary physician, and he really helped me. He used Talwin to detox me off of the Vicodin. It proved to be an excellent pain medicine for me. I don't know if it's my constitution, but I am not addicted to Talwin NX. If I run out and can't get to my doctor or whatever, I do not experience any withdrawal symptoms."

8 / 10
Was this helpful?YesNo
47 Report
  • bil...
  • March 5, 2008

Naloxone / pentazocine for Pain "Stronger pain med, is a Schedule 3 drug, so it's not as hard to get a prescription for. I take it for severe back arthritis pain, and it works wonders. Not as hard on the liver as drugs containing Tylenol. Stay away from Tylenol if you have liver disease."

7 / 10
Was this helpful?YesNo
40 Report
  • Shy...
  • December 22, 2013

Naloxone / pentazocine for Chronic Pain "Talwin was first given to me when I had wrist surgery to reattach tendons and ligaments torn from the bone during a car accident. Plus, I have fibromyalgia and psoriatic arthritis. And I'm allergic to all the morphine, codeine types. My wrist surgeon coupled Talwin NX with Phenergan, and it worked like a charm. Now, I use that very combination for psoriatic arthritis flares. It's wonderful!"

10 / 10
Was this helpful?YesNo
22 Report
  • 5st...
  • January 15, 2014

For Chronic Pain "I have been taking this med for many years, and it still works great. It has greatly improved my quality of life. I have had several cervical neck surgeries, and I have lived with chronic pain for many years. This medication has been a lifesaver for me, and I would recommend it to anyone living with chronic pain. Thank you."

9 / 10
Was this helpful?YesNo
16 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • miz...
  • Taken for 5 to 10 years
  • January 21, 2014

Naloxone / pentazocine for Chronic Pain "Great medicine for controlling pain/chronic pain. Non-addictive. The nclenal stands for Nicene, which is arcane. An opioid and drug overdose reversal medication. It works by blocking opioids and other addictive medications from building up in cells/body. As Talwin contains small amounts of opioid, the amazing thing about this medication is while using it for chronic pain, it took away all mental urges or desires to think about drinking alcohol, which I had stopped years before but had those mental desires or thoughts to drink. Cravings, so to say. It may have the same long-term result for addicts who crave other drugs... amazing! An important fact that is not a warning from the drug company is it blocks relax meds before procedures such as colonoscopy, relax medication. Scary."

10 / 10
Was this helpful?YesNo
22 Report
  • par...
  • October 4, 2011

For Pain "I take the generic form (PENTAZOCINE-NALOXONE TABLET). I have fibromyalgia. I moved to GA around 3 years ago, and luckily my last pain management physician was able to refer me to a doctor in a nearby town. I travel 132 miles round trip to him monthly. At the point of seeing him, I was in real bad pain, and he prescribed naloxone/pentazocine generic. This medication has helped me. I take a steady 1 to 2 every 4 hours. It is more rare now to take 2. I know it is masking the pain, and it does not mess with my head. I can get into major pain at times. It passes, I think easier because I have a steady level in my system."

10 / 10
Was this helpful?YesNo
16 Report
  • Joe...
  • Taken for 1 to 2 years
  • March 26, 2020

Naloxone / pentazocine for Chronic Pain "Complete joke! I’ve had 9 different back surgeries, and I was in horrific pain the entire time. I thought very seriously about suicide to relieve the unbearable pain. I finally retained an attorney and sued the pain management doctor. The judge said his treatment amounted to sadistic torture. I won my case and was able to hire a compassionate doctor. Talwin made me feel severely anxious and sick the entire time that I took it. I would never take it again."

1 / 10
Was this helpful?YesNo
11 Report
  • Anonymous
  • Taken for less than 1 month
  • May 29, 2012

Naloxone / pentazocine for Pain "Hydrocodone wasn't providing relief through the entire duration between doses, and the doctor wouldn't prescribe more frequently because of my 'body size.' Oxycodone didn't touch the pain, so the doctor prescribed Talwin NX. I developed severe hives by the second dose and developed breathing problems. Didn't take a third dose, and it didn't help with my pain that much. Have sacroiliac joint dysfunction with severe pain and lumbar pain with cycling muscle spasms. Am allergic to steroids, so trigger point injections didn't work either."

2 / 10
Was this helpful?YesNo
21 Report
  • Anonymous
  • April 24, 2010

For Pain "I have a congenital birth defect called Arnold-Chiari Malformation. Part of my brain sticks out the back of my skull and pushes against my spinal cord. I live in a small town and had a difficult time getting my pain managed because I was in my late 20s and was told I couldn't receive pain pills until I was older. (Backwards and shameful, I know.) I resisted attempts to make me submit to brain surgery because I have Factor V and a history of DVT and PE. After spending nearly 3 years of my life bedridden with severe pain in my head, eye, neck, and spine, unable to work or study, a physician finally gave me this medication. It gave me my life back, and nobody questions the fact that I am young and seeking only pain relief in order to function."

9 / 10
Was this helpful?YesNo
16 Report
  • Mar...
  • March 31, 2018

Naloxone / pentazocine for Pain "During an armed robbery, I was shot 3 times, a month in a coma, major open abdominal exploratory surgeries to repair damage and stem the loss of blood, leaving large wounds and 150+ stitches/staples and ribs wired back together, bullet fragments in my spine and nerve damage. But I was alive and could barely walk, but the Talwin Nx was a tremendous help to allow me to ease the pain, so I could function and do minimal tasks through the day. It did such a good job at blocking the pain that I had to use discretion after I took it, not to overdo it, as I might bust open any stitches, though I felt little discomfort at the time. My doctor prescribed them with no issues for about a year, and as I healed more, my frequency between doses of all my meds, including the Talwin, lengthened. Initially, I would take 1 every 4-6 hours as prescribed, then I got to where maybe 1 a day would get me through the day. But after that and without access to pain meds, the quality of life was lessened."

9 / 10
Was this helpful?YesNo
8 Report
  • Rog...
  • January 8, 2014

For Chronic Pain "I've been on this medicine for five years and it is the best pain relief for my knees and back. Still can't do much on this medicine, but it takes away the pain. Lay down after taking for best results."

10 / 10
Was this helpful?YesNo
10 Report
  • jus...
  • March 15, 2008

For Pain "I am prescribed Talwin NX for chronic left leg pain due to having numerous strokes, seizures, and two heart attacks. I have also been diagnosed with Crohn's disease. I think this medication works very well, and when I don't take it for a while, I have no adverse reactions (withdrawals). I have also not formed a dependency on this medication, unlike other narcotic pain medications I have been prescribed."

9 / 10
Was this helpful?YesNo
15 Report
  • wea...
  • Taken for 1 to 2 years
  • October 15, 2021

For Chronic Pain "This medication has been working great for me for about 2 years. No side effects whatsoever. I have back issues, PAD in my legs, plantar fasciitis, and bone spurs in my feet. Out of the blue I can’t get Pentazocine/Naloxone for a few months now. Is anyone else having trouble? I have been prescribed Belbuca, but even starting at the bottom, it’s far too expensive. Please help."

10 / 10
Was this helpful?YesNo
4 Report
  • ani...
  • Taken for 5 to 10 years
  • June 21, 2016

Naloxone / pentazocine for Chronic Pain "I was on this for most of the '80s and '90s. No need to up dosage, I would give anything to get them again. Last year, I weaned off morphine because it was too low of a dose: 60 mgs per day! I moved, and back home I got up to 120 mgs of methadone per day. Plus, pain docs are very scarce here, the few there are either won't take new patients and/or my insurance. So, to answer the question: Talwin NX works really well on pain. It can cause anxiety in some people."

9 / 10
Was this helpful?YesNo
8 Report
  • Wor...
  • July 8, 2019

Naloxone / pentazocine for Chronic Pain "I had a head-on collision with my car and another vehicle in 1996. My neck, shoulder, and back were affected. Initially put on Loritab, but I was nauseated and also worried about becoming dependent. I then tried the injections in my back and did pain management. My job was physically demanding, and it was difficult to just walk. My doctor prescribed me Talwin NX about 10 years ago. Initially, my pharmacist told me that it was an older pain medication and that I needed my doctor to change me over to Loritab or something else. I told the pharmacist my concerns about opioids, and he has started keeping the Talwin Nx to fill my prescriptions. I only take them when I need to be very active. Thirty pills usually last me 45-60 days, as the most I have taken in a day is 1 pill. I have gone without taking any for over a week. I have been injured multiple times since that car wreck but will only take Talwin for my pain."

10 / 10
Was this helpful?YesNo
5 Report
  • Anonymous
  • May 3, 2011

For Pain "I was prescribed this medicine after having one of my lower large molars pulled. I ended up with a dry socket and in horrible pain. This is a great pain reliever without the side effects like the others. I will use it again if needed."

7 / 10
Was this helpful?YesNo
10 Report
  • Jon...
  • December 11, 2019

For Chronic Pain "I was first prescribed Talwin (pentazocine) after I became allergic to hydrocodone and oxycodone. I did develop a tolerance to both those drugs and had to up my dosage. My orthopedic doctor wanted me to try Talwin. He said it was an old-school pain reliever. I started out on 2 every four hours. After being on it for five years now, I take three every four hours. It just flat takes away the pain without getting high. I have no plans on going to a higher dose. If I forget and take too much, I either start itching or throwing up. It works just as well today as it did when I was first prescribed it. I think those who are in need of real pain relief that don’t like the effects of hydrocodone or oxycodone should give Talwin a try. It just flat works for my type of pain, which is osteoarthritis in my hands, back, and neck."

10 / 10
Was this helpful?YesNo
3 Report
  • men...
  • March 10, 2017

Naloxone / pentazocine for Pain "Worked like a charm for pain and anxiety for migraines. You have to start slow and get used to it. After that, it's better than mother's milk and a safe alternative to oxys. Opana, an old school drug when people were responsible and didn't need so much control. Do they still make it in the old form? Don't drive, though. Remember."

8 / 10
Was this helpful?YesNo
5 Report
  • Anonymous
  • Taken for 10 years or more
  • December 16, 2022

For Chronic Pain "I’ve been on this for 17 years now, after about two years of using other pain meds. They just kept me in the worst condition with the high, but my doctor recommended this, and it’s a wonder pain medication for me, no high, just pure relief."

10 / 10
Was this helpful?YesNo
1 Report
  • ela...
  • October 28, 2008

Naloxone / pentazocine for Pain "TALWIN NX is the only drug that relieved the pain in my upper spine. I have been taking two a day for 12 years and have not needed to increase the dosage. To me, it was a miracle drug."

10 / 10
Was this helpful?YesNo
44 Report
  • Anonymous
  • February 9, 2011

Naloxone / pentazocine for Pain "Worked great for my back pain."

8 / 10
Was this helpful?YesNo
26 Report
  • Lad...
  • October 12, 2007

Naloxone / pentazocine for Pain "This medication was prescribed for constant back pain. While taking Talwin Nx, I was mean, irritable, and had the shakes."

3 / 10
Was this helpful?YesNo
31 Report
  • Anonymous
  • December 6, 2009

Naloxone / pentazocine for Pain "Was given this for pain, had bad shaking, very anxious and irritable. Also dizzy and nauseated."

1 / 10
Was this helpful?YesNo
24 Report
  • Tan...
  • March 27, 2017

Naloxone / pentazocine for Chronic Pain "Used Talwin NX for Carpal Tunnel. Worst feeling ever! I felt drunk, carsick, had horrible dreams - it did not help with pain relief. I would not take it again!"

2 / 10
Was this helpful?YesNo
7 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.