Metronidazole for Clostridioides difficile Infection User Reviews (Page 2)

• Anon
• Taken for less than 1 month
• January 5, 2018

"I was dx'd with cdiff Dec 29th after taking amoxicillin clavunate. I was given Flagyl 500mg 3x day for 14 days. I am 8 days in and feel awful. Nauseous, loss of appetite, light-headed at times, slight headache, fatigue, but restless, no energy. Mostly nauseous in the AM's. Ended up in the hospital Jan 3rd and got IV fluids as I was dehydrated. Praying for a fast recovery for everyone with this. Drinking a lot of water right before and after taking the med helps."

• Anonymous
• April 17, 2012

"Taking this medication for 10 days for C diff. I am on day seven right now, and it's been horrible. 41-year-old, female, had bloody and mucus and bad diarrhea. I think medicines have fixed the diarrhea and bloody mucus for now, but I am so dizzy. I feel even sicker in other ways. It's causing me major shortness of breath, fatigue, nausea, confusion. Found out the hard way that even putting lotion on my face or body that have any alcohol in them will make you feel even worse on this medication."

• Just_
• Taken for less than 1 month
• July 27, 2019

"I am on day 3 of this stuff after being switched from vancomycin due to a reaction I was having from it. This is the most awful medication I have ever been on. This stuff makes you feel wicked out of it . I spent all morning crying. I’ve been depressed, extremely exhausted , agitated ... My bottom left eye turned pink about half an hour ago and I’ve got no idea why?! Brain fog to the extreme, I don’t even feel like this is real life . All started from C.Diff , I can’t stress how important it is too wash your hands . I've turned into a germ a phobe"

• Marknn
• January 24, 2016

"Was proscribed Metro 400mg three times a day for Clostridium infection. Within few days I was experiencing stomach gurgling and bubbling that was diabolically strong and constant It would keep me awake all night and be going literally all day. I was terrified to eat and became so upset. I have never been ill with my tummy before and consider myself a strong and robust 44 year old man with no prior mental/gastro health problems but this drug literally destroyed me. Jury's out whether it's worked or not. The clostridium diarrhea HAS gone (though stools still aren't right and stomach is still sore ) yet to have tests to confirm."

• Jbsun...
• Taken for less than 1 month
• February 7, 2018

"Day 7 of 14 on this med, I came down with C-Diff after a round of Augmentin, and Biaxin 3 weeks before that. I too had Nausea, but that got a little better once I could get solid food in my stomach with ginger ale and Nauzene in my pocket for the quick draw. I can't shake the weakness feeling, tired, run down, just spent. I have been unstable on my feet and confused. I can't tell if the c-diff is winning or Metronidazole is winning. I hate to spend the money but Vancomycin has to worth a shot."

• Emano
• Taken for less than 1 month
• April 24, 2018

"I was prescribed metronidazole 3x500mg for 10 days for mucus and blood in stool (my problems started after a treatment of levofloxacin). This is the most horrible drug I've ever taken. After two days I started having abdominal cramps and diarrhea. The side effects just got worse and worse up to the point that I had diarrhea at least 15 times a day, all solid and pureed food went through me after an hour and the cramps were so painful that I feared I was dying. I cannot comment on its effectiveness, because I had to discontinue the treatment on day 6 due to the severe side effects - which only began subsiding a week after stopping taking the medication. The very annoying part for me was that how protective my physician talked about both levofloxacin and metronidazole when I mentioned that I was probably suffering from the side effects."

• Jane
• November 1, 2018

"I took one pill/dose of this combination and it the worst. It is a garbage drug. I stopped taking it after one dose and after a night of cold sweats, 6 blankets on the bed, multiple runs to the bathroom. I am STILL awake since.. Tuesday evening since I went to the ER. This is a crap combo of a drug and don’t take it. My primary even refused to change my order until I told the ER nurse my story."

• Mel
• March 3, 2020

"Took 1500mg metronidazole a day. I was able to manage three pills a day for a short time. Now I wish I had never taken it. I had to go to the emergency room several times. Each time, they told me it was because of my C Diff infection but I did not think so. I was throwing up blood and had an intense burning sensation in my stomach. It felt like I had a bunch of hot needles throughout my entire digestive tract, specifically my stomach. They took me off of the medicine early but then put me back on it when my infection returned. Second time around was even worse than the first. More ER visits. Over a year and a half later I am now unable to eat the foods I want and regularly throw up during the night time. Honestly, my life sucks now. Please, if you can afford something else, TAKE IT!! Yes it "worked", but there are better alternatives to this drug. I could have taken Vancomycin and I would be okay today. This drug is too dangerous to be on the market & has completely stripped my stomach."

• Yaits...
• August 22, 2015

"I'm on day 6 of 10 for C-diff and don't feel there is much of an improvement. The taste is horrible! I've had the worst anxiety attacks from this along with daily headaches. I think I could sleep all day and night with this stuff. I'm hoping I start to feel better soon"

• Rain
• Taken for less than 1 month
• October 7, 2019

"I was put on Flagyl after vancomyacin wasn't effective in clearing my cdiff infection. 5 days into taking it my arms went numb and my right leg. I called Dr and was told to stop taking it. 2 days after I stopped other symptoms starting showing up. Blurred vision, dizziness, trembling, depersonalization, ear pain, eye pain, severe anxiety, insomnia, stomach pain like being eaten from the inside out, racing heart, blood pressure 180/100. I was like a zombie. Of course the Dr didn't believe I could have all these symptoms after I stopped. So needless to say I had to help myself. I joined the Flagyl toxicity support group on Facebook. Learned Flagyl depletes Thiamine and magnesium. So I began magnesium theronate and AllThiamine. It helped tremendously. I thought I was getting better and then two months down the road joint pain sets in. Thumbs, fingers, knees, back. I'm at a loss on what to do about this. Whatever you do don't take Flagyl it will mess you up."

• Antioch
• Taken for less than 1 month
• October 13, 2019

"This is the 14th day taking this metronidazole for C. Diff, colitis, and E. Coli infections. It has been one of the most miserable times in my life. It definitely cleared up the infections, and I can appreciate it's a effectiveness and low cost. The side effects for me included constant nausea, metal taste in my mouth, brain fog, and insomnia even though I took it with a full meal. It is a horrible pill to swallow and I am glad that this is my last day. Hopefully, I will begin to feel normal and I will be done with this "off" feeling."

• Anonymous
• September 6, 2011

"Took 4 days for diarrhea to stop but side effects were terrible nausea, upset stomach, insomnia, dizziness. Didn't have the bad taste just finished the last pill thankfully wouldn't want to take it again."

• Jam
• Taken for less than 1 month
• October 15, 2019

"I was prescribed Metronidazole 500mg 3 times a day for c-diff after having a reaction from Vancomycin. It seems to be helping my diarrhea but I CAN NOT take the side effects anymore! The taste in my mouth is making me throw up, I can't eat, I'm dizzy, can't sleep, I just can't take it anymore!"

• hurti...
• Taken for less than 1 month
• August 5, 2014

"I have been taking metronidazole 500mcg 3 times daily for 7 days for C-Dif. The side effects are awful, stiff neck, painful urination, back, leg, hip, knee, ankle and overall joint pain are terrible. I reported this to my MD, who encouraged me to keep taking the med for 10 days to be sure the c-diff infection is gone. So, I am still taking it. Right now, I only hope that once i manage 10 more pills, that the pain and hurt will go away. This is without a doubt a very toxic medication and not much you can do except take it anyway..... Can someone out there let me know if the joint pain goes away after you quit taking this stuff? Is there something that I can do to avoid permanent joint damage?"

• Anonymous
• Taken for less than 1 month
• October 23, 2022

"I would recommend drinking something thick like ensure or something with a lot of flavor to try and mask that nasty taste. Pills dissolve very quickly so avoid soda or hot beverages… I experienced dark urine, a lot of gas and burps, and some light headaches"

• Lainey
• Taken for less than 1 month
• October 31, 2019

"After presenting in the ER with C-diff, I was prescribed Flagyl. Took as prescribed but within 24 hrs was so ill. I went to a DIFFERENT ER by ambulance. I was admitted and within 24 hrs had my entire colon removed, went into renal failure, developed fluid buildup in my lungs. Was in the ICU FOR 10 days and in the hospital for 5 1/2 weeks. Life long injury! Brink of death because of this ineffective drug!!!!"

• Cano
• April 23, 2021

"Nothing severe but very drowsy, emotional, I empty my bowels 7 times a day and it’s very soft and feeling nauseous. I use this medication for a tooth infection. I recommend taking probiotics while taking this medication."

• Kcole
• April 9, 2021

"I recently started taking this medication and am on day 3 for my c diff infection. I honestly do not know what’s worse, the side effects from this medication or the c diff itself. I am constantly nauseous, especially right After my morning dose. It makes my mouth so dry to the point where I can’t even chew or swallow food, COMPLETE loss of appetite. I am extremely fatigued but feel on edge ? I would not recommend this medication to anyone there has got to be something that causes less suffering."

• Stevo
• Taken for less than 1 month
• March 16, 2021

"Was prescribed 1x500 every 8 hours for C-Diff which I developed after taking infusions of Vancomyacin two times daily to treat a bone infection in my foot. I am diabetic and after three weeks of vancomyacin I broke out into an allergic reaction leading to the doctor prescribing this. I was nauseous for two days and had a headache and was very tired. Completely lost my appetite and had to force myself to eat anything. After day three I began having stomach cramps and diarrhea. I also had blurry vision and my knees and joints all over hurt. I drank no alcohol and limited my coffee. Really couldn't stand this drug but it did successfully treat the C-Diff infection"

• KRD
• Taken for less than 1 month
• June 26, 2022

"I have been taking this medication for 2.5days, after getting the results on that my two week episode is due to a c diff infection. I also have colitis and assumed it was another flare up. I’m reading reviews about the tabs, the liquid form is way better in terms of taste, some side effects still persist but the suspension form is miles better than the pill so I highly recommend requesting that. Still no major improvement but I will have to continue on. Dose is 30ml a day."

• Anonymous
• Taken for less than 1 month
• October 3, 2022

"After finding out I had a C Diff infection without any symptoms (stool test was for something else), I was prescribed 3x 400mg a day of Metronidazole. After doing my research and listening to what the doctor had to say, I took the tablets for 6 days in which the side effect were bearable - lightheaded, dizzy, bloating, minor stomach cramps, loss of appetite, taste. However out of nowhere on day 6 I was hit with irritability, agitation, sadness that quickly turned into depression, dread and suicidal thoughts. I stopped the tablets and will see how I recover, it has only been 24 hours. I’ve never felt like this before. Non stop crying and not knowing what to do with myself. Speaking to my doctors shortly but no doubt they won’t associate it with the tablets yet so many people have these side effects! If you have a c diff infection, I would suggest doing your research - maybe I’m in the so called “small group of people” who have these effects."

• Hak
• Taken for less than 1 month
• November 18, 2021

"Terrible nausea on this medication. I was prescribed 400mg x 3 per day for 10 days for c diff. It’s improved the symptoms of c diff within a few days but it truly is an awful medication to take. It tastes disgusting and the taste lingers in your mouth constantly. I had awful nausea using it and dreaded each time I had to take a tablet. Even though my appetite was gone I was dry heaving because of the metronidazole. I also had some odd visual disturbances. I caught c diff after being given 4 different types of IV antibiotics in hospital for a bacterial infection. I’m using a probiotic to try and avoid getting c diff again after the course of metronidazole ends. C diff is horrendous and if I have to use metronidazole again then I will even if it takes all of my willpower to finish the course. I’ve had an awful lot of heavy duty antibiotics recently but I have to say that metronidazole is amongst the worst for side effects even if it is effective for cdiff."

• Captain
• Taken for less than 1 month
• June 1, 2022

"The effect of this drug on my brain cannot be understated. I began to have peripheral neuropathy, extreme panic, and depression. I didn't know how I would make it through the time it would take tor the drug to wear off because it was so difficult for me to swallow saliva or food from panic and the sense of pure mental torture. I somehow made it through these seconds and minutes and hours as the feeling of poison gradually diminished, was given vancomycin which was wonderful and side effect free for me. I healed from cdiff, and from the neurological effects from metronidazole, but not all have been so fortunate."

• Snick...
• Taken for less than 1 month
• September 24, 2018

"Okay...pretty worried about starting these meds after what I’ve read here. I was prescribed this medicine in Friday for treatment of c.diff. 500mg 3x a day for 10 days."