Metoclopramide and Anxiety: What Users Say (Page 4)

• Kat...
• Taken for less than 1 month
• September 5, 2017

Metoclopramide for Migraine "Do not take this medicine. One-time IV dose. Causes nervous system damage. First Parkinson's side effects, then anxiety after five months not gone. Possible sensitivity to other medications. Horribly traumatic. Couldn't work."

• Qui...
• September 22, 2017

Metoclopramide for Migraine "Given IV with Toradol & Benadryl. My headache went away almost immediately. Soon after that, I started shivering and trembling. I dismissed it, thinking I was just cold because of the hospital temperature & the IV fluids. I also had to pee so bad that I unhooked it myself because I could not wait for the nurse to come in and help me. I was so restless and anxious that I drove home, knowing the nurse told me to call a ride, but it's like I couldn't control the urge to just make it home and go to bed. I didn't realize that all of those symptoms were side effects of the medicine until I got home & started to tremble more & was unable to sleep. Since then, I've been having panic attacks & anxiety, muscle stiffness & twitches. DO NOT TAKE."

• Kam...
• Taken for less than 1 month
• June 22, 2019

Metoclopramide for Migraine "OMG, where do I begin? Was in the emergency room for severe migraine and nausea. They gave me this drug through my IV. Never again. I began to sweat, I started cursing and screaming, I was so anxious and delirious. It was a terrible experience. I feel like I needed to just run out of the hospital. Do not recommend."

• Jc1...
• Taken for less than 1 month
• April 26, 2020

For Migraine "I went to the ER with a hypertensive crisis. Once they got my BP stable, my severe headache was still very persistent, so the doctor prescribed metoclopramide and Benadryl. Unlike many others here, I had absolutely no anxiety to the Reglan. My headache was alleviated within 15 minutes, and within a few hours, I was able to go home."

• AAa...
• Taken for less than 1 month
• June 11, 2017

Metoclopramide for Migraine "Went to the ER for high blood pressure and was having a bad headache as well. Was given Reglan cocktail and afterwards I have had the worst anxiety ever. I wanted to rip the IV out of my arm and run out of there. I will never let them give me those meds again."

• Kit...
• October 27, 2019

Metoclopramide for Migraine "I went to the E.D. 2 nights ago for a massive headache, the worst headache I have ever had in my life, and I was miserable and dry heaving. When I finally got pulled back, they gave me the 'headache cocktail' with Reglan, Benadryl, and Toradol. The nurse started taking the blood pressure in the same arm as my IV. While it was squeezing my arm, it was shooting pain in my arm. The fluids were painful in my arm, and I kept begging for them to take them out. I had a massive panic attack and couldn't keep my legs still. I started feeling like I needed to get out of my own skin, and my clothes were strangling me. I started begging for them to let me leave because I HAD TO go. It took about 30-45 min for me to actually calm down. My headache went away, but I freaked out both my mom and my boyfriend. It was one of the worst experiences of my life. While I was leaving, the doctor was like, 'Oh, yeah, one of the medicines can wind you up and give you anxiety like that.' Thanks, glad you tell me this now."

• Bea...
• Taken for less than 1 month
• June 26, 2022

Metoclopramide for Migraine "I'm not kidding when I tell you this medication made me feel a way I never want to feel again. I have since listed this medication as an allergy because I refuse to go through what this medication put me through. I was losing it inside the ER after being given this. Could not sit still and wanted to rip my IV out. I would have rather felt a migraine/nausea than be given this. Would not wish this medication on my worst enemy. Very jittery and uneasy throughout your body. Please be advised."

• Bea...
• Taken for less than 1 month
• June 26, 2022

Metoclopramide for Migraine "I'm not kidding when I tell you this medication made me feel a way I never want to feel again. I have since listed this medication as an allergy because I refuse to go through what this medication put me through. I was losing it inside the ER after being given this. Could not sit still and wanted to rip my IV out. I would have rather felt a migraine/nausea than be given this. Would not wish this medication on my worst enemy. Very jittery and uneasy throughout your body. Please be advised."

• Anonymous
• June 5, 2019

Metoclopramide for Migraine "OMG, worst medicine mixture ever!!! I’ve had this terrible stuff 2 times. The first time, I went to the ER for an awful migraine, and they gave me Compazine, Reglan, and Benadryl, and immediately I started feeling very tired but restless and anxious at the same time. I wanted to sleep, but I couldn’t because I felt like I just wanted to run out of there and just go home! It’s the worst anxious feeling I’ve ever experienced. So, the next time I had a migraine, they wanted to give me that, and I thought, well, maybe it was just a bad reaction last time or something, but NOPE! I had the same feeling, and they wanted to do an MRI on me because of other neurological symptoms I came in with, but since I was feeling so awful, I just told them, nope, I want to be discharged. I’m definitely going to tell them next time those medications I cannot tolerate, and I refuse them."

• Mar...
• Taken for less than 1 month
• March 7, 2023

Metoclopramide for Gastroparesis "This medicine is a nightmare! Took the pills today to get rid of yucky burps and nausea. Started feeling even more queasy, then my chest felt like it was going to explode. Got sleepy and jittery at the same time and had anxiety through the roof. Hours later, still feeling mildly crazy, and all it took was 10 mg. It fixed the symptoms but wasn't worth the side effects. Don't do this to yourself. Stay away!"

• Mar...
• Taken for less than 1 month
• March 7, 2023

Metoclopramide for Gastroparesis "This medicine is a nightmare! Took the pills today to get rid of yucky burps and nausea. Started feeling even more queasy, then my chest felt like it was going to explode. Got sleepy and jittery at the same time and had anxiety through the roof. Hours later, still feeling mildly crazy, and all it took was 10 mg. It fixed the symptoms but wasn't worth the side effects. Don't do this to yourself. Stay away!"

• Bsc...
• Taken for less than 1 month
• April 20, 2025

Metoclopramide for Nausea/Vomiting "Ok. I have several health issues, and today is the first day in a long time I feel decent. I was in the hospital with sepsis last month and have been battling recurring urinary tract infections and pneumonia. I got a tick bite a few days ago, got nauseous, and went to the ER. The doctor prescribed doxycycline and Reglan. I’ve never felt better!! I also have gastrointestinal issues from a medication I take. This stuff and Zofran are amazing. I’m taking the pill version, so maybe that’s why I’m not having a bad experience. Now, Compazine is a whole different story! It was given IV, and I went nuts. Panic, fear, and heart palpitations made my nausea worse! IV Benadryl in the hospital helped too."

• emi...
• Taken for less than 1 month
• August 26, 2019

Metoclopramide for Nausea/Vomiting "My experience was a nightmare. It was one of the worst experiences of my life. It gave me severe anxiety and a sense of dread. The nurses and hospital staff couldn't get ahold of a physician to give me something to counteract it, and they were out of Benadryl. Yes, the hospital was out of Benadryl. I couldn't take the anxiety, and I ripped out all my IVs and ran out to my car and left. That's how bad the panic was."

• Nan...
• March 13, 2016

For Migraine "I've never written any reviews on the internet before, but after my experience in the ER last night, I googled the effect of Reglan and Benadryl on headaches just to see how others react, and I feel better that many reacted like me, so I'm not crazy. So they gave me Reglan and Benadryl IV push. I was just ready for relief. Little did I know everything started moving so fast, I was scared for my life. My husband was in the waiting room with our sons, but I started texting him to come back, but I couldn't even compose a text. The door was shut, and the lights were dim, and I had the worst anxiety attack. I've never felt like that in my life. Called for hubby, begged him to ask the doc to let me go... which he did. Eventually, I felt better at home."

• Sam...
• Taken for 1 to 6 months
• July 28, 2015

Metoclopramide for Nausea/Vomiting "Was given Reglan at ER for severe vomiting. My heart began to race, and I felt extremely jittery and anxious. As sick as I was, I couldn't even lie down anymore, I was so 'hyped up.' They had to give me Ativan to reverse the effects of the Reglan. Never again."

• Sam...
• Taken for 1 to 6 months
• July 28, 2015

Metoclopramide for Nausea/Vomiting "Was given Reglan at ER for severe vomiting. My heart began to race, and I felt extremely jittery and anxious. As sick as I was, I couldn't even lie down anymore, I was so 'hyped up.' They had to give me Ativan to reverse the effects of the Reglan. Never again."

• Che...
• January 8, 2017

Metoclopramide for Migraine "Visited the ER due to an intense migraine lasting 7 days with 4 impacted wisdom teeth coming in. Face swollen, migraine, and intense anxiety went to a different hospital and was hoping for something that worked, but got the Reglan/Benedryl cocktail which made me freak out like an idiot, and I cried for anxiety meds when a new doctor came in and denied me anything else and called me a pill popper, although the only meds I'm taking are for my teeth pain (antibiotic and a steroid) and also continued to be rude while still having an outrageous migraine. Home now... hours later... with a migraine still......"

• Anonymous
• August 11, 2018

For Migraine "The reason so many of these reviews are negative, with reports of anxiety, is because the Reglan wasn’t mixed into an IV fluid bag and instead pushed. The nurses in all those ERs should have known not to push IV Reglan. Always ask to check drug interactions with a care provider that can’t clearly state the possible side effects. Also, they should just know."

• Anonymous
• Taken for less than 1 month
• September 7, 2017

Metoclopramide for Nausea/Vomiting "I will never take Reglan ever again! Worst experience of my life! As soon as they gave me Reglan through my IV, I started having crazy racing thoughts, fast heart rate, felt anxious, and had anxiety, couldn't stop moving, and was sweating profusely. NEVER AGAIN."

• Anonymous
• Taken for less than 1 month
• September 7, 2017

Metoclopramide for Nausea/Vomiting "I will never take Reglan ever again! Worst experience of my life! As soon as they gave me Reglan through my IV, I started having crazy racing thoughts, fast heart rate, felt anxious, and had anxiety, couldn't stop moving, and was sweating profusely. NEVER AGAIN."

• Tay...
• Taken for less than 1 month
• December 10, 2020

For Nausea/Vomiting "Took this for a few weeks after being prescribed it to help pregnancy morning sickness. I was fine for a couple of weeks until the anxiety started. I’ve never been an anxious person, but this medication put me into a severe and dangerous state. I was suddenly so anxious I couldn’t eat or sleep for 5 days. I thought I was losing my mind. I immediately stopped the medication, but weeks later I’m still dealing with the anxiety. I’m now on Zoloft and needing to be closely monitored by a perinatal mental health team. I went from having amazing mental health to being a complete mess and dreading being pregnant. I am so upset my doctor prescribed me this without warning me. I will NEVER take medication again without doing research on it. I wish I had my sane mind back!!!! Don’t take this!!! Especially if you suffer from anxiety."

• RAC...
• Taken for less than 1 month
• November 19, 2022

Metoclopramide for Migraine "Reglan caused me to experience major anxiety and panic attacks within minutes of receiving it via IV. Made me feel like I was dying. The anxiety attacks took a few months to subside. Horrible drug, wouldn't recommend to anyone."

• Mar...
• Taken for less than 1 month
• June 11, 2019

Metoclopramide for Migraine "6/10/19 I received the migraine cocktail for the first time. The doctor was very careful to push the Reglan slowly into the IV. At first, I felt fine, but once she left the room, I got hot, sweaty, and anxious. I had full-body tremors, sweat through my clothes, and felt like I needed to rip the IV out and run. My severe migraine is gone, but I would recommend not trying this medication if you already have anxiety or if you’re sensitive to medications."

• Ted...
• January 23, 2017

Metoclopramide for Migraine "I went to the ER with a migraine I had had for about 4 days. I was given this medication. I was in so much pain. I was so anxious. I told them I was still in pain. My blood pressure was going up and down. I will never let them give this to me again. I was there 6 hours and left with no relief. I felt like I was tortured. Reglan and Benadryl."

• Anx...
• Taken for less than 1 month
• September 9, 2022

Metoclopramide for Lactation Augmentation "Was prescribed this for increasing my very low milk supply (I'm breastfeeding). I was excited because I feel horrible not being able to breastfeed my newborn. Took literally 2 or 3 pills over a couple of days and suddenly had severe chest pain, chest tightness/pressure, couldn’t breathe well, and had an anxiety/panic attack during the middle of the night. I’m 3 weeks postpartum and have struggled some with anxiety and heart palpitations (due to PVCs I’ve had forever just getting more elevated), so I assumed it was just postpartum related. But it got so bad I freaked and thought I had a pulmonary embolism or something since those can happen after birth. Went to the ER, had blood work done and a CT scan to rule out anything life-threatening. Got home just stumped... until I realized the only thing I’d done differently was take Reglan. Looked up these reviews and knew that’s exactly what caused it! Will NOT be finishing these."