Methenamine for Prevention of Bladder infection User Reviews

• Ste...
• August 24, 2011

Hiprex (methenamine) "I was suffering from regular severe urinary tract infections, taking multiple courses of antibiotics each time, only to feel relief for a few weeks before getting another infection, despite drinking 2 liters of water per day, taking cranberry supplements, and washing and urinating before and after sex. Since taking Hiprex, I have not had an infection in several months. The only negative is that the tablets taste awful."

• Mag...
• Taken for less than 1 month
• September 28, 2019

Hiprex (methenamine) "I have been on Hiprex for 3 weeks. I had a bladder infection, and after taking the antibiotic, the doctor has put me on Hiprex. I find I am tired all the time on this drug. Mild headache. It is working for the bladder."

• Rik...
• Taken for 5 to 10 years
• March 15, 2021

Hiprex (methenamine) "I have a long-term urethral catheter. I used to get frequent UTIs. I seem to be permanently on antibiotics. My neurologist suggested using Hiprex. I started using it about nine years ago, and since then, I have only had two infections. I have found no side effects, and I just need an annual renal function blood test."

• Deb...
• Taken for 6 months to 1 year
• August 13, 2020

Hiprex (methenamine) "Retention of urine was creating a reservoir for bacteria to flourish and was the cause of the repeated UTIs over several years. I had a urethra dilation, which has led to better flow and more complete bladder emptying. I also take Hiprex once a day and have not had an infection for nearly a year. Bliss. The tablet itself tastes awful, but a small price to pay."

• Ann...
• Taken for 6 months to 1 year
• August 10, 2019

Hiprex (methenamine) "I am in London, and my GP prescribes Hiprex to prevent constant UTIs. The drug has been successful, but there has been no supply in my area, so I have bought it in Australia at a reputable pharmacy that ships overseas. Hiprex is bought over the counter in Australia, which is useful. I paid for it via PayPal, which takes your money about the same time as the delivery. In my case, after delivery. I bought two bottles of 1g Hiprex. The total cost was £63.21, which included airmail. I paid VAT on the purchase when it arrived in the UK. Found them efficient to deal with. I rang the distributor in the UK, and they said supplies were being sent out on August 12th. Someone told me they are going to switch manufacturing to the UK. I hope so. I hope my experience helps others."

• neu...
• November 27, 2008

Mandelamine (methenamine) "Thousands of patients with neurogenic dysfunction of the lower urinary tract were treated by me with Mandelamine 1g three times daily for the past 20 years, with very good results and without any side effects. It decreased urinary infections in this group of patients by about 60 - 70%."

• Met...
• Taken for 5 to 10 years
• September 28, 2014

Mandelamine (methenamine) "I've used Mandelamine/Methenamine for 7 years, and it works for me. I never get less than a year between infections, but I am now 2 years and 9 months without an infection after previously trying almost every medicine available with mixed results. Sometimes I'd get a breakthrough infection after 2 months, and other medicines would last 5 weeks, being taken every day. I've had no bad effects, taking 1 MG at bedtime, but I do drink the glass of water with it. I get overnight discomfort if I don't."

• Boo...
• February 22, 2018

Hiprex (methenamine) "I am coeliac, so vigilant with diet. I have urine retention (300 ml). My specialist thought it was contributing to my recurrent urinary tract infections, so I started on Hiprex only last week, 2 times daily, along with cranberry juice and a probiotic, but I have had a UTI for 4 weeks. Initially on antibiotics for two weeks prior to starting Hiprex for the UTI, I have felt no improvement. I drink lots of water, no coffee, no dairy, or gluten. How long does it take before I can expect Hiprex to start to have an effect?"

• Lee...
• Taken for 2 to 5 years
• November 16, 2020

Hiprex (methenamine) "I have been on Hiprex for 2 years and only had 1 UT as opposed to a UTI every few months. My Dr. prescribed it twice a day, morning and night, with a cranberry supplement pill and 500 mg vitamin C tablet. It does taste terrible, but better than the alternative."

• sau...
• December 23, 2015

"I have been on this medication for a month and am so happy about this. I was getting UTIs all the time for over 15 years. This medication is a godsend! I have no pain or infections. My UTIs were so severe I had to go to the ER, couldn't wait for my MD. I do drink a lot of water with this medicine too, about a gallon a day. I highly recommend this medicine for chronic UTI sufferers."

• Lis...
• March 7, 2022

Hiprex (methenamine) "Hiprex has worked for me after I have suffered from UTI problems for over 4 years. A urologist said to use it when I feel I am starting with an infection, and I use it for two weeks, and it seems to stop any infection from progressing. Wish I had known about it earlier, as it has made my life so much better."

• Tjs...
• Taken for 1 to 2 years
• October 29, 2016

"Went on vacation in the Dominican, came back with a UTI. Not the souvenir I wanted. I believe I got it from the filthy water I swam in. Haiti is on the other side and has no sewer system. If you swim with a tampon in and don't remove it right away, it will stew with the ocean water. I struggled for a year, and I ended up taking Ceftin for 3 months straight in order to kill the multi-drug resistant E. coli that had invaded my bladder cells. It took 3 months to shed the lining of my bladder with the invaded cells. My urologist put me on Hiprex for bladder maintenance. It works! I'm a med tech and dip my urine and look at it under the scope constantly, my urine stays acidic and no E. coli would want to take up residency."

• Anonymous
• February 15, 2012

"I take the generic methenamine. I have not had any side effects and no new infections in months. After years of various antibiotics and recurrence in a few weeks, I am grateful this is still on the market. It was an infectious disease doc (not my urinary doc) who prescribed it."

• Gol...
• Taken for 2 to 5 years
• March 7, 2021

Hiprex (methenamine) "I've been on Hiprex for almost 3 years, and during that time, I've had multiple infections of the urinary tract and bladder. I'm meticulously clean and will not go to strange public dirty toilets. I bought supposedly non-perfumed wipes, but actually, they had perfume, and I have now a severe urinary tract infection with a temperature and feeling very ill, even though I have Hiprex twice a day as prescribed by the professor in a hospital."

• tic...
• Taken for less than 1 month
• June 9, 2019

"Just wanted to share my experience for others, as unfortunately, I had bad effects with this drug. I have had UTI infections for many years and had reconstructive surgery on my ureters, so I am prone to infection. When I started methenamine, I began getting painful urination and abdominal pain, which I thought was UTI again. I also seemed to start having a lot of swelling in my nose too. I got tested for infection, but nothing was present, and the pain was awful, I couldn't understand it. Decided to come off the pills, and my symptoms seemed to improve. I think I had an allergic reaction to them. Although I don't know what I am going to use to stop the infections now, I will have to speak to my doctor."

• Rac...
• Taken for 6 months to 1 year
• December 10, 2021

"I've been getting UTIs for over 20 years, ever since giving birth to my children. I've been on Bactrim for a year (until it stopped working), Keflex for a year (until that stopped working), and also Amoxicillin for a year (until that stopped working). At this point, I realized I was steadily developing resistance to too many antibiotics, and this isn't a good long-term plan. But without antibiotics, I was getting 2-3 UTIs a month. Finally, I discovered Hiprex (Methenamine Hippurate) and asked my urologist about it. He was fine with prescribing it for me. At first, it gave me headaches, but then I discovered that sometimes people experience headaches when they ingest both Hiprex AND caffeine. It has to do with increased vasodilation. So anyway, I gave up the caffeine and the headaches went away. I now take 1 Hiprex 1000mg tablet twice a day with 500mg ascorbic acid (vit C). Going on 1 whole year with no UTIs! Awesome! Be careful to keep urine pH below 6.5 and invest in urine pH test strips."

• per...
• Taken for less than 1 month
• December 11, 2021

Hiprex (methenamine) "I have lower urinary tract disease. I previously had many recurring UTIs for many years. The urinalysis failed to grow cultures, so it was dismissed by the medical profession and treated with antibiotics. I was prescribed Hiprex by the urinary specialist nurse. I have not had an infection since. The LUTS was very painful and stressful, which I have suffered for many years."

• Mar...
• Taken for 1 to 6 months
• July 10, 2018

"After 7 UTIs in 18 months, I went on antibiotics for 3 months, after which I started on Methenamine Hippurate. After about 2.5 months, I developed severe bladder pain and spasms typical of another UTI with significant incontinence. Urinalysis showed no signs of infection, I attributed the symptoms to a side effect of the drug and stopped taking it. While the pain and spasms have subsided, the incontinence has persisted for a month already. In my case, the cost and side effects cancel out any benefits."

• Anonymous
• Taken for 6 months to 1 year
• March 3, 2023

"Before this Rx, I took Macrobid daily for a couple of years. When I changed my care from a male urologist to a female urogynocologist, the first thing she did was take me off Macrobid and put me on this med. I am so grateful. As long as I take this Rx as prescribed, I have no issues, no side effects, no bladder infections. So happy to be off daily antibiotics!!"

• Mmc...
• Taken for 1 to 6 months
• July 14, 2014

Hiprex (methenamine) "I have been on this for about two and a half months, seems to be working. Very excited about it."

• Maw...
• Taken for less than 1 month
• November 29, 2020

Hiprex (methenamine) "I have tried taking Hiprex a few times, but after a few days, I get itchy eyes. Does anyone else suffer from this? Just wondering if it could be something else, and I am blaming Hiprex wrongly."

• j b...
• August 29, 2008

"Have been using methenamine for prevention of urine infection for 14 years, and it works very well. I recommend this drug."

• Flo...
• June 8, 2019

Hiprex (methenamine) "Been on these tablets for just over 2 months. My bladder was so inflamed I called these my miracle tablet, but now have a job getting them from my pharmacy or anywhere where I live in the UK."

• On...
• Taken for 1 to 2 years
• September 21, 2021

Hiprex (methenamine) "Been on it with vitamin C for 18 months. Tried to go off it twice but the infection comes straight back within 24 hours. Happy it is there though."