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Lysine and Stomach Pain: What Users Say

Brand names: L-Lysine, L-Formula

Stomach pain: mentioned by 3 users (2.5%)

Based on user experiences from 118 Lysine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

pain 10.2%
itching 6.8%
tingling 3.4%
cramps 2.5%
stomach pain 2.5%

Reviews for Lysine

Commonly mentioned side effects
  • Hap...
  • July 18, 2016

For Herpes Simplex (HSV) "One day I got a severe headache. It lasted for 3 full days. I was tired, could barely move, pain all over. I developed a rash, almost like chafing on my inner thighs next to my lady parts. I knew it was herpes, so I went and got tested, and sure enough, it was positive for simplex 2. Being 25 and only having two partners really narrowed down where I got it from. I am still with the person who gave it to me. Anywho. I was prescribed generic Valtrex (acyclovir), it cleared up the rash in about a week. But it had harsh side effects: leg pain, stomach pain, etc. I researched lysine and began taking it after my 10 days of acyclovir. It has been 3 months and no further outbreak. I had my cycle and felt that viral tingle, I increased the lysine and no outbreak."

9 / 10
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19 Report
  • Mr ...
  • Taken for less than 1 month
  • June 27, 2020

For Herpes Simplex (HSV) "Began taking 500-1000 mg twice daily to suppress a recurrent sore/bump on the rear side of my palate. This increased greatly in recurrence due to immunosuppressive drugs for another condition. The lysine seemed to work for about a week, but now is possibly causing frequent stomach/gut pain and cramps. Might stop lysine and see if stomach cramps resolve, then resume dosing at a lower level, maybe 250 mg 2X daily. I skipped a dose or two to see what would happen, and the mouth sore came right back. But I'm not sure the stomach cramps are tolerable, since I already have Crohn's with a lengthy stricture..."

5 / 10
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3 Report
  • Mr ...
  • Taken for less than 1 month
  • June 27, 2020

For Herpes Simplex (HSV) "Began taking 500-1000 mg twice daily to suppress a recurrent sore/bump on the rear side of my palate. This increased greatly in recurrence due to immunosuppressive drugs for another condition. The lysine seemed to work for about a week, but now is possibly causing frequent stomach/gut pain and cramps. Might stop lysine and see if stomach cramps resolve, then resume dosing at a lower level, maybe 250 mg 2X daily. I skipped a dose or two to see what would happen, and the mouth sore came right back. But I'm not sure the stomach cramps are tolerable, since I already have Crohn's with a lengthy stricture..."

5 / 10
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3 Report

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