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Inclisiran for High Cholesterol User Reviews (Page 3)

Brand names: Leqvio

Reviews for Inclisiran

Commonly mentioned side effects
  • rog...
  • Taken for 6 months to 1 year
  • May 19, 2024

Inclisiran "Not sure if this is related to Leqvio or not, however, since beginning the Leqvio regimen I have experienced an increased level of muscle and joint pain and reduced mobility."

6 / 10
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24 Report
  • Dav...
  • Taken for 1 to 6 months
  • August 6, 2023

Inclisiran "Leqvio works very well to lower the LDL cholesterol, but I am having substantial weakness in my legs. No other side effects. Would hope there is some way to eliminate the weakness."

10 / 10
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26 Report
  • Eli...
  • Taken for 1 to 2 years
  • May 22, 2024

Inclisiran "Had high hopes, but too many gastrointestinal side effects. Also muscle pain and stiffness. Lowers cholesterol but 2 months after the shot, I still have side effects."

7 / 10
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18 Report

Frequently asked questions

  • L h...
  • Taken for 6 months to 1 year
  • May 28, 2024

Inclisiran "It has lowered my LDL. However, I have noticed that my skin started to wrinkle a great deal after my third shot. Has anyone else experienced this symptom? It is my only adverse reaction."

8 / 10
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15 Report
  • Ano...
  • Taken for 6 months to 1 year
  • June 5, 2025

Inclisiran "My cholesterol is better, but I hurt all over! I don’t know if Leqvio is causing this, but I feel like I didn’t hurt this bad before!"

6 / 10
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4 Report

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  • Anonymous
  • Taken for 6 months to 1 year
  • May 6, 2023

Inclisiran "Took first dose in October 2022. Bad cholesterol was 105. Second dose in January. Bad cholesterol was 45 in February. Cardiologist was amazed!! Feel much better this summer."

10 / 10
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18 Report
  • Mor...
  • Taken for 1 to 6 months
  • October 9, 2024

"Hair loss second month. I have fine hair, can’t afford to lose anymore."

6 / 10
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6 Report

More FAQ

  • Anonymous
  • Taken for 1 to 6 months
  • January 13, 2025

Inclisiran "After my first injection, all seemed fine, but two weeks in I have arthralgias of the fingers and severe constipation, dry lips."

4 / 10
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4 Report
  • Jay...
  • Taken for 1 to 6 months
  • September 5, 2024

Inclisiran "Painful joints when moving around after sitting. Troublesome cough. Feeling nauseous frequently, especially in the morning before breakfast."

7 / 10
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5 Report
  • Mar...
  • Taken for 6 months to 1 year
  • April 18, 2024

Inclisiran "Leqvio helped me lower my cholesterol levels significantly. I cannot take statins because of the bone and muscle pain. However, I have bone and muscle pain even with taking Leqvio."

9 / 10
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6 Report
  • phi...
  • Taken for less than 1 month
  • July 9, 2025

Inclisiran "Just had my first injection 7 days ago and I'm just experiencing lower back pain on the 6th day."

1 / 10
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1 Report
  • Tho...
  • Taken for 2 to 5 years
  • January 1, 2024

Inclisiran "Worked for me, been taking it for a couple of years."

10 / 10
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6 Report
  • Ano...
  • Taken for 1 to 2 years
  • June 11, 2025

Inclisiran "I’ve been getting Leqvio shots for a year and a half now. I haven’t gotten any side effects so far. My cholesterol levels have dropped quite a bit. I’m satisfied with the results."

10 / 10
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1 Report
  • Anonymous
  • April 15, 2024

Inclisiran "Lowest numbers I have ever had. Not aware of any side effects."

10 / 10
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3 Report
  • Mfs...
  • Taken for 6 months to 1 year
  • March 29, 2025

"So far, so good, nearly 12 months' use in conjunction with pravastatin."

8 / 10
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1 Report
  • jac...
  • Taken for 1 to 6 months
  • February 29, 2024

Inclisiran "Massive drop in LDLs with Leqvio. Medication was prescribed by my cardiologist, and Medicare with Supplementals paid for its EXPENSIVE costs."

10 / 10
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2 Report
  • lee...
  • Taken for less than 1 month
  • November 27, 2023

"No problems at all. Took the shot on 9/27/2023. No side effects."

10 / 10
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0 Report
  • Ano...
  • May 27, 2025

Inclisiran "Just had my 3rd shot. No issues at all. Total cholesterol went from 292 to 167. Very happy with results."

9 / 10
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0 Report
  • Ano...
  • Taken for 6 months to 1 year
  • August 4, 2025

"Having a runny nose all the time and chest congestion. Also have NSCLC and have been treated with radiation and chemo. Low-grade fevers every!"

10 / 10
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0 Report
  • Emm...
  • Taken for 1 to 2 years
  • May 23, 2025

Inclisiran "It has lowered my cholesterol a lot, but my doctor wants my good cholesterol increased. I have some trouble with 'charlie horses' in my legs. Am hoping that decreases so I can continue the medication."

7 / 10
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0 Report
  • Ano...
  • Taken for 1 to 6 months
  • August 7, 2025

"No problems, only had the first injection 4 weeks ago, so don't know if it's working, but no side effects yet."

7 / 10
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0 Report
  • Inc...
  • May 30, 2025

"Cholesterol levels reduced but side effects including breathlessness, acute joint pain, congestion, and cold-like symptoms."

5 / 10
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0 Report
  • Ano...
  • Taken for 1 to 2 years
  • May 26, 2025

Inclisiran "Has worked well for me. Will recommend it to others."

10 / 10
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0 Report
  • Hel...
  • Taken for 1 to 2 years
  • May 21, 2025

"I've had 3 doses, no side effects, feel great, couldn't tolerate statins, side effects were really bad, couldn't get out of bed in the morning, aches, pains everywhere. Highly recommend inclisiran."

10 / 10
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0 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.