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Imiquimod topical for Human Papilloma Virus User Reviews (Page 2)

Brand names: Aldara, Zyclara

Imiquimod topical has an average rating of 7.1 out of 10 from a total of 257 reviews for the treatment of Human Papilloma Virus. 61% of reviewers reported a positive experience, while 20% reported a negative experience.

Reviews for Imiquimod topical

  • Lucie
  • July 1, 2020

Aldara (imiquimod) "The cream worked amazingly! My warts cleared away within 2 weeks of using the cream. The skin where the warts were is now smooth and wart free. However, it was incredibly painful- cream causes severe skin reactions. For me I developed sores and blisters on my vagina after the first week. When I peed it felt like my skin was on fire because it made contact with the blisters. I found I couldn't sit or walk without being in agony. However I persisted as and by the end of the week it was clear. Some tips ! -aloe vera is your best friend. Apply it as often as you can because it will help with the blisters and irritated skin -when peeing, take a class of cold water and pour it at the same time, or squired bottled water. This really helps with the burning and stinging. Also apply aloe vera after peeing -DONT apply to much cream or leave it on for more than 10 hours. I think lathering the cream on didn't help the severe reactions I was having"

10 / 10
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  • Prude...
  • Taken for 1 to 6 months
  • November 18, 2019

Aldara (imiquimod) "Female age 53, after an operation to remove the bad cells I have been prescribed Aldara cream to use 3 times a week, I actually feel like I’m being tortured the burning and stinging is unbearable, in such a sensitive place it’s making me feel terrible, I have got to use this for 16 weeks. For VIN3 and I am going back to my specialist on Thursday. Any one have any suggestions what I can do x"

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  • Chuck...
  • May 15, 2015

"I really screwed up with this medication. I put too much on and just thought the burning was it working. I had one small anal wart and thought I would 'go hard or go home.' I went hard with the cream, and I had a horrible reaction to it. My skin was so raw I could not walk. If water touched it in the shower, it was a pain unlike any I have felt. Washing it burned, sitting hurt, walking hurt, sneezing hurt, going to the restroom was painful beyond belief, everything made it hurt. Just be very careful and only apply a tiny amount to the affected area. Don't be stupid like me. It does work great, but can be unbearably painful if used wrong. It will heal if you do go overboard, but it takes a week or so of pampering."

8 / 10
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Frequently asked questions

  • Popma...
  • January 2, 2020

Aldara (imiquimod) "I had a GW 12 days ago, at 1st its a small flat white warts, So my OB prescribed me Aldara 3-5x a day in 10 days & some antibiotics 2 times a day in 10 days. On the 4th day of my application, I felt burning & redness down there until 2 small blister showed up between the small warts. Also felt side effects same as the other experience, fever like feeling. On the 8th day, the small white wart vanish but the 2 small blister still remains. I’m totally freaking out. On the 9th day, 1 blister gets bigger and turns out to be white as well as the other small blister. On the 10th day whenI visited my doctor, She told me to stop the cream & prescribed me multivitamins. She told me to get a surgery or burn the warts when I get to decide. 11th day i stopped Aldara but the two white blister is still there. And still my V is swollen. I don't know what to do anymore. Will this white blister still go away cause I stopped using aldara already? Any same case as mine? Need help."

6 / 10
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  • Wart...
  • Taken for 1 to 6 months
  • November 10, 2014

"I had hundreds of warts all over me. I was advised to use this cream despite the fact that its use on a large scale hadn't been tested. I'll admit that it took lots of packets to complete the whole treatment, but in four months, every single wart was completely gone. There wasn't a single spot left. This cream worked where every other treatment, including surgery, did not."

10 / 10
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Are you taking this medicine?

  • Eric
  • June 15, 2017

"This drug works well at killing warts, but it's best to start with the tiniest amount to check how your body responds to it and then ramp it up if you don't get a strong response. I didn't follow the boilerplate '3 times a week' usage guidance because this was too slow for me. I used it every day and amply, until after about 1 week when the 'blistering' effect started to kick in, then I backed off. The negative reviews from people who got bad reactions are missing the point a little. The whole idea of the drug is to ramp up an immune response in the area you apply it. The red blistering/rash/swelling, etc. is precisely what you want: this is the immune system doing its work."

9 / 10
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  • Its...
  • Taken for less than 1 month
  • April 11, 2017

"I was prescribed Zyclara about 3 weeks ago, instructed to put it on once daily for 8 weeks. Look, I'm not going to sugarcoat it. This cream is meant to take action and get rid of your unwanted skin virus symptoms, so yes, there will be tingles, maybe some burning, and definitely some soreness, but I would do it again in a heartbeat. A little goes a long way, and for me, it takes a couple of days to show results, but the key is it does! I take 'heal days' if needed and take care of myself by eating right and taking multivitamins. I went to weekly freezing prior, which eventually worked but came back, but so far with the cream, no returns! One more stubborn one to go! Don't be scared to try it, and don't give up. Your life is not over :)"

10 / 10
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More FAQ

  • Freeme
  • September 12, 2017

"Long story short. Imiquimod is the best thing that ever happened to me! It got rid of my unsightly, nasty genital warts and boosts my immune system to fight them always. I felt strange my first use, my heart beats fast, head hurts, areas of my genitals swelled up and caused warts on other areas. When that happens, your viral load is HIGH! Now I look down there, and my confidence is back, all thanks to this special drug. I wish some people would stop downing it. Without imiquimod, there would be no help for my condition."

8 / 10
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  • male
  • Taken for 1 to 6 months
  • October 20, 2019

Aldara (imiquimod) "I got HPV despite having safe sex from an erotic massage place. The sample analysis resulted it's HPV 16 and 56 which are both high risk. The doctor removed them by cauterization - horrible process. A year later I realised I still have a couple of small points. I used Aldiq which is basically another brand of Aldara made in Italy and it had great results. With one box - 3 times a week they almost dissapeared. I becamed a bit obssessed with this and now I'm checking my penis with the magnifying glass and noticed that there is a little bit of affected tissue which is healing very slowly. Aldara basically made the first layer of the skin dry and I think it's forcing the area to regenerate. I gave it a 9. Important - I used it Monday, Wednesday and Friday in the evening after a shower and after I've let my body cool down. I think it's important for the affected area to be inspected with a magnifing glass which some dermatologists have. Hang in there. It will take some time but we'll get over it :)"

9 / 10
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  • abc
  • April 11, 2021

Aldara (imiquimod) "Always wondered if I would ever get to leave a review on here. After 8 months I finally stopped using Aldara. To be honest, I don't even know if it was the cream or just time that got rid of the warts. I never had a huge outbreak but they were stubborn. It started with two bigger ones. They decreased in size after using the cream but never really went away. I ripped most of them off to be honest. I know how you guys feel. I was severely depressed during this time. Side effects were non existent in the beginning but after some time they were horrible: My skin got so thin that it ripped all the time (I mean huge tears like after giving birth), I've had constant yeast infections and couldn't pee without being in pain (put your hands on the floor while peeing, thank me later). I don't want to scare anyone but I was fooled by reviews that promised me that it will all be gone after a month. You're normal, not alone and you will eventually fight it."

5 / 10
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  • Lemon
  • Taken for less than 1 month
  • October 31, 2019

Aldara (imiquimod) "I had genital warts on my anus. I was so terrified when I notice something strange round the back. When I check through mirror there is small tiny round thing and I didn't know what is was. I go direct to check on google what is it and I got shocked! I have been so depressed knowing that I have Genital Warts. I went to dermatologist and he did cryotheraphy it works, around 3 days my small tiny thing has gone. I had sexual intercourse and it comes back. I didn't tell to my dermatologist but he told me that it may come back so he prescribe aldara to me for 3 weeks every other day. And now I'm 2 years warts free. This products really works. No pain. No hassle."

9 / 10
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  • Breat...
  • Taken for less than 1 month
  • July 4, 2014

"I was very nervous using this, reading what other people have experienced with side effects. I decided to try it under advisement from my gynecologist. I have 4 small warts. One on my labia, one just inside of it, 2 around my anus. I've been using imiquimod for about 10 days, 3 times a week, 6 hours at a time. In that time, I have seen SIGNIFICANT changes in the 2 on my vaginal area. They are almost completely gone. The other two are being a little more stubborn. I wanted to share some good comments about this medication after being so worried about it myself before. Zero skin irritation. I've had some 'flu-like' symptoms, but nothing unbearable. I'm very happy to see these 'aliens' shrink away. Try it before you knock it!"

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • August 18, 2015

"I have been using this cream for a month now, and I see results, most of my g warts are gone. It takes time and patience. I know it's an embarrassing disease to have, but there is hope, it's not a death sentence. So far, this cream is working for me. I noticed it does cause irritation if you overdo it, but other than that, I recommend it."

9 / 10
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  • Anony...
  • April 14, 2015

"This cream is one of the most painful and agonizing treatments I have ever received, however, if you are willing to put up with insatiable itching, burning, feeling like you have the flu, and being unable to catch your breath, it is 100% worth it. For me, the few months of pain are worth it to get rid of the embarrassment and self-disgust at having GW. I'm just starting to recover from the treatment and have gone from maybe 30 to around 5 tiny ones (I have an immunity disorder, so I was unable to fight the virus myself and it spread so quickly). Fantastic treatment, absolute agony, but well worth it if you can put up with it."

9 / 10
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  • L Bri...
  • Taken for less than 1 month
  • November 16, 2014

"It works, but it hurts! This is my fourth day using it, and I'm seeing results. The first three days, it itched and made the warts more pronounced and sore (my doctor told me to use it every day and not three times a week.). Today, I've noticed significant changes. A large cluster of about four is gone, but the skin is really irritated. I think there's like three left, but they're not that big. I'm so sore, but at least they're going away. Suggestions: Take a Benadryl before you apply the cream. Decrease the itching, and it'll knock you out. Protect your skin with Vaseline. Get some sterile bandages to cover your 'healing' areas between applications because you will have some... drainage... I guess that's the right word."

8 / 10
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  • Anonymous
  • May 3, 2019

"Used imiquimod for HPV (a couple of genital warts) for 1 month at three times a week. After applying 2 times I started noticing an intense itch/burn in treated area. Aloe gel would cool n soothe the itch /burn, then started using ice packs, quit using toilet paper & have a bottle of water to rinse with instead. The itch is everywhere. Started applying Emla cream 2.5% lidocaine to all areas (local anesthetic. Freezing it stops the itch and numbs the burn. Realizing the itch is all new warts coming to surface. I'm well into my 4th week. Been told 6 weeks use from day started but with each continuous outbreak your 6 wks starts over. No less that 15 with the hood of my clitoris being the center of about 80% of them. I now use witch hazel, calamine, vitamin e & a 5% lidocaine med called jampocaine. I still wake in the night scratching from new ones breaking out. Horrible experience right from the start. Need this to be gone. Huge hit to my confidence. The pain literally consumes me. I even went back to gyno. He looked said its bad but its doing its job. So I'm sticking it out"

9 / 10
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  • Spike
  • October 25, 2012

"This cream really is a miracle. The first few times I used it on my warts, I did not pay attention to only putting it on the warts, I applied it to the general area, and the itching was unbearable. But after paying closer attention to my application, my warts have very noticeably gotten smaller or disappeared after only two weeks of treatment. My side effects were itching, slight sting when applying, slight swelling, and just some overall discomfort. But the side effects were nothing compared to being on a wart-free track!"

8 / 10
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  • Gener...
  • Taken for less than 1 month
  • July 26, 2019

Aldara (imiquimod) "I had genital warts. I decided to try Aldara and to hope for the best. After reading loads of reviews about crazy side effects I was a bit worried, but my experience has been great. It says use each sachet only once but I get at least 3/4 uses out of each. I’ve had no burning and minimal scabbing of the skin, only a slight bit of redness around the affected area. After 2 weeks the warts began to shrink rapidly and disappeared in the 3rd week! Just ensure you follow the instructions and complete the course (~16 weeks) as I’ve noticed a lot of people have stopped using it once the warts disappear and then they come back straight away. It cost me £70 for the whole course."

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • March 22, 2016

"This stuff works for GW. I was diagnosed about three months ago, and I tried acid 3x before to burn them off. It seemed like it irritated them, and more would pop up. Started using this cream 3 weeks ago on MWF nights, and all my GW are gone!!! Other things I think helped were taking an immune system booster supplement, drinking water, and rubbing coconut oil for the in-between days (Tues. Thur.) for the itching and the dryness that the cream causes... All together, I'm pleased with the results, and the side effects weren't any worse than the regular itch that you get from general warts.. Sticking with this routine really helped me, and I hope this is helpful to someone else. GW are not forever!!!"

9 / 10
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  • Doc...
  • Taken for less than 1 month
  • July 9, 2021

Aldara (imiquimod) "I strongly recommend everyone research AHCC (Active Hexose Correlase Compound) which is a potent shiitake mushroom extract. It has been shown to boost the immune system to a level where it completely eradicated the papiloma virus in lab mice, and has been used in clinical trials on people. It is perfectly safe and it works. Do you research, then help yourself. :) Peace"

5 / 10
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  • Effec...
  • September 3, 2014

"I had warts a few years back and used the cream. They recently reappeared but I'm using the cream again. It was very effective the first time around. I didn't have to use it for that long before seeing improvements! Hoping for a similar experience this time around."

7 / 10
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  • max
  • March 15, 2017

Aldara (imiquimod) "I'm fighting HPV for a year and half now Aldara works but it takes long time be patient it might burn you some times make sure the area is clean and dry avoid using tea tree oil or ACV while on Aldara therapy"

7 / 10
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  • Elenaa
  • August 20, 2014

"For all people who have genital warts, my only advice is: use Aldara cream. It's amazing. I had three warts, one big and two small ones. I went to see the gynecologist, she gave me this cream. After three applications, everything is gone. I don't have any more. However, I still have some of them inside, that's what the pap smear shows. But the inside ones need different therapy. Aldara cleared all my outside warts in one week. Don't hesitate, use it, but you need to check with your doctor if you have other warts inside."

8 / 10
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  • Girli...
  • January 11, 2017

"I've been using for about 2 weeks now, I have warts right by vaginally entry and surrounding lips. First week I didn't really feel much difference but now I am in SO much pain from the burning! Going to the toilet and sitting down without screaming in pain are my biggest challenges...rightly or wrongly I've read other' stories, as well as a dermatologist article who all infer burning means it's working (for those that don't know it is a chemical burn cream, that's how it gets rid of the warts). I haven't stopped using it as the warts are going, but if anyone can offer ways to relive the pain and confirm I'm still going to have a fully functioning vagina at the end of this (laugh, you have to with these things!) I'd be super grateful!..."

5 / 10
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  • Jady
  • Taken for 1 to 6 months
  • June 19, 2017

Aldara (imiquimod) "About 6 month ago I noticed some tiny warts about 13 on the base of my penis so I had them checked from a dermatologist. He told me they look like Boweoid Papulosis and warts. He recommended Aldara and told me to put a thin layer on them for 4 weeks. 3 times a week. Absolutely nothing happened during this period. When I saw him again he gave me another 8 weeks (2 packets). I am on my 8th week now and no change except I think they may be getting slightly bigger. I have not had sex with my partner for the last 6 months and due this problem I am getting more and more depressed. I am losing hope with this medication and am not sure where to turn too. I would be much obliged for any advice given."

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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Human Papilloma Virus

Symptoms and treatments